Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity Article Swipe
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· 2023
· Open Access
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· DOI: https://doi.org/10.1371/journal.pone.0289502
Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant ( p = <0 . 001 ) HRQoL VAS score55.1 (±23.2) of patients with the obesity. HRQoL VAS scores of patients with obesity were found to be higher when compared to patients with both T2D 49.8 (±15.4) and HTN 48.2 (±21). Diagnosis of one, two and three diseases showed significant results in VAS with all variables including gender ( p = 0 . 004 ), educational level ( p = <0 . 001 ), marital status ( p<0 . 001 ), residence ( p = <0 . 001 ), financial situation ( p = <0 . 001 ) and monthly income ( p = <0 . 001 ). The most frequently observed extremely problematic dimension was anxiety/ depression (47%) and the self-care (10%) was the least affected . Patient HRQoL is decreased by T2D, HTN, and obesity. The impact of these diseases coexisting is more detrimental to HRQoL.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pone.0289502
- https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289502&type=printable
- OA Status
- gold
- Cited By
- 20
- References
- 27
- Related Works
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- OpenAlex ID
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- OpenAlex ID
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https://openalex.org/W4385567814Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1371/journal.pone.0289502Digital Object Identifier
- Title
-
Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidityWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-08-04Full publication date if available
- Authors
-
Shahid Shah, Ghulam Abbas, Ayesha Aslam, Fawad Ahmad Randhawa, Faiz Ullah Khan, Haris Khurram, Usman Rashid Chand, Muhammad Hammad Butt, Tauqeer Hussain Mallhi, Yusra Habib KhanList of authors in order
- Landing page
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https://doi.org/10.1371/journal.pone.0289502Publisher landing page
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289502&type=printableDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289502&type=printableDirect OA link when available
- Concepts
-
Medicine, Obesity, Comorbidity, Diabetes mellitus, Type 2 diabetes, Quality of life (healthcare), Type 2 Diabetes Mellitus, Internal medicine, Visual analogue scale, Population, Cross-sectional study, Physical therapy, Mann–Whitney U test, Multivariate analysis, Environmental health, Endocrinology, Pathology, NursingTop concepts (fields/topics) attached by OpenAlex
- Cited by
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20Total citation count in OpenAlex
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2025: 9, 2024: 11Per-year citation counts (last 5 years)
- References (count)
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27Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.patients | 33, 54, 74, 87, 97, 143, 169, 198, 206, 217 |
| abstract_inverted_index.sampling | 65 |
| abstract_inverted_index.status). | 111 |
| abstract_inverted_index.Diagnosis | 227 |
| abstract_inverted_index.Pakistan. | 61 |
| abstract_inverted_index.Whitney-U | 180 |
| abstract_inverted_index.conducted | 51 |
| abstract_inverted_index.decreased | 317 |
| abstract_inverted_index.dimension | 300 |
| abstract_inverted_index.disorders | 12 |
| abstract_inverted_index.extremely | 298 |
| abstract_inverted_index.financial | 275 |
| abstract_inverted_index.including | 242 |
| abstract_inverted_index.measuring | 108 |
| abstract_inverted_index.performed | 115 |
| abstract_inverted_index.residence | 267 |
| abstract_inverted_index.responded | 88 |
| abstract_inverted_index.score55.1 | 195 |
| abstract_inverted_index.self-care | 307 |
| abstract_inverted_index.situation | 276 |
| abstract_inverted_index.technique | 66 |
| abstract_inverted_index.variables | 241 |
| abstract_inverted_index.chi-square | 117 |
| abstract_inverted_index.coexisting | 328 |
| abstract_inverted_index.completing | 90 |
| abstract_inverted_index.depression | 303 |
| abstract_inverted_index.frequently | 296 |
| abstract_inverted_index.instrument | 106 |
| abstract_inverted_index.prevalence | 17 |
| abstract_inverted_index.regression | 127 |
| abstract_inverted_index.stratified | 63 |
| abstract_inverted_index.Statistical | 112 |
| abstract_inverted_index.detrimental | 331 |
| abstract_inverted_index.educational | 251 |
| abstract_inverted_index.population. | 20 |
| abstract_inverted_index.problematic | 299 |
| abstract_inverted_index.significant | 185, 235 |
| abstract_inverted_index.Mann-Whitney | 119 |
| abstract_inverted_index.Multivariate | 125 |
| abstract_inverted_index.comorbidity. | 82 |
| abstract_inverted_index.hypertension | 1 |
| abstract_inverted_index.individually | 39 |
| abstract_inverted_index.standardized | 105 |
| abstract_inverted_index.questionnaire | 103 |
| abstract_inverted_index.statistically | 184 |
| abstract_inverted_index.Kruskal-Wallis | 123 |
| abstract_inverted_index.health-related | 27 |
| abstract_inverted_index.multifactorial | 11 |
| abstract_inverted_index.questionnaire. | 92 |
| abstract_inverted_index.cross-sectional | 48 |
| abstract_inverted_index.multimorbidity. | 45 |
| abstract_inverted_index.questionnaire-based | 47 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 98 |
| corresponding_author_ids | https://openalex.org/A5012711430, https://openalex.org/A5018518758, https://openalex.org/A5051209608, https://openalex.org/A5051954629, https://openalex.org/A5050522489, https://openalex.org/A5019507257, https://openalex.org/A5019590111, https://openalex.org/A5062816729, https://openalex.org/A5101539220, https://openalex.org/A5079523875 |
| countries_distinct_count | 4 |
| institutions_distinct_count | 10 |
| corresponding_institution_ids | https://openalex.org/I123387679, https://openalex.org/I142016965, https://openalex.org/I194348271, https://openalex.org/I199702508, https://openalex.org/I201384688, https://openalex.org/I87445476 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/1 |
| sustainable_development_goals[0].score | 0.6000000238418579 |
| sustainable_development_goals[0].display_name | No poverty |
| citation_normalized_percentile.value | 0.96213415 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |