Assessment of health related quality of life (HRQol) in patients with Meige’s syndrome Article Swipe

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Alok Kumar Verma , Pavan Kumar Singh , Saurabh Agarwal , Babita Gupta ·

YOU? · · 2018 · Open Access · · DOI: https://doi.org/10.18203/2320-6012.ijrms20181961

Background: There is paucity of literature regarding health related quality of life (HRQoL) in Meige’s syndrome (MS) especially from India. This study assessed HRQoL in its global and disease specific aspect by previously validated instruments in patients with Meige’s syndrome.Methods: The study was performed in AIIMS, New Delhi. Subjects with Meige’s syndrome as well as age and gender matched healthy controls were enrolled from Movement Disorder and botulinum toxin clinic, Department of Neurology, AIIMS, New Delhi. Uneducated patient, those could not read questionnaires and cases who had received botulinum toxin within 6 months were excluded from the study.Results: A 14 pts of Meige’s syndrome were enrolled and 14 age matched controls were taken. All the pts of Meige’s syndrome scored worse in SF-36 as compared to controls in areas of role physical (p =0.002), bodily pain (p = 0.001), general health (p = <0.001), social functioning (p = 0.05) and role emotion (p = <0.001). 50% of patients with Meige’s syndrome had depression out of whom 21.4 % had moderate depression. Patients with Meige’s syndrome had significantly impaired scores in 10 of the 12 subscales which was profound in areas of ocular pain, near activities, distance activities, social functioning, role difficulties, dependency, driving, compared to borderline impairment in general vision, mental health, color vision.Conclusions: This study clearly demonstrated that pts with Meige’s syndrome, suffered from significant impairment in HRQoL as compared to controls. Higher proportion of patients with Meige’s syndrome suffered from moderate depression compared to their control. Pts with Meige’s syndrome had severe impairment of vision related quality of life.

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Medicine Depression (economics) Quality of life (healthcare) Botulinum toxin Neurology Physical therapy Pediatrics Psychiatry Surgery Macroeconomics Nursing Economics

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Type: article
Language: en
Landing Page: https://doi.org/10.18203/2320-6012.ijrms20181961
PDF: https://www.msjonline.org/index.php/ijrms/article/download/4925/3941
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Cited By: 1
References: 15
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DOI: https://doi.org/10.18203/2320-6012.ijrms20181961

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Title: Assessment of health related quality of life (HRQol) in patients with Meige’s syndrome

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Language: en

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Publication year: 2018

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Publication date: 2018-04-28

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Authors: Alok Kumar Verma, Pavan Kumar Singh, Saurabh Agarwal, Babita Gupta

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Landing page: https://doi.org/10.18203/2320-6012.ijrms20181961

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Concepts: Medicine, Depression (economics), Quality of life (healthcare), Botulinum toxin, Neurology, Physical therapy, Pediatrics, Psychiatry, Surgery, Macroeconomics, Nursing, Economics

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Cited by: 1

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abstract_inverted_index.Subjects	48
abstract_inverted_index.assessed	22
abstract_inverted_index.compared	124, 203, 230, 244
abstract_inverted_index.control.	247
abstract_inverted_index.controls	60, 110, 126
abstract_inverted_index.distance	195
abstract_inverted_index.driving,	202
abstract_inverted_index.enrolled	62, 105
abstract_inverted_index.excluded	94
abstract_inverted_index.impaired	177
abstract_inverted_index.moderate	169, 242
abstract_inverted_index.patient,	77
abstract_inverted_index.patients	36, 157, 236
abstract_inverted_index.physical	131
abstract_inverted_index.profound	187
abstract_inverted_index.received	87
abstract_inverted_index.specific	29
abstract_inverted_index.suffered	223, 240
abstract_inverted_index.syndrome	15, 51, 103, 118, 160, 174, 239, 251
abstract_inverted_index.Meige’s	14, 38, 50, 102, 117, 159, 173, 221, 238, 250
abstract_inverted_index.botulinum	67, 88
abstract_inverted_index.controls.	232
abstract_inverted_index.performed	43
abstract_inverted_index.regarding	6
abstract_inverted_index.subscales	184
abstract_inverted_index.syndrome,	222
abstract_inverted_index.validated	33
abstract_inverted_index.Department	70
abstract_inverted_index.Neurology,	72
abstract_inverted_index.Uneducated	76
abstract_inverted_index.borderline	205
abstract_inverted_index.depression	162, 243
abstract_inverted_index.especially	17
abstract_inverted_index.impairment	206, 226, 254
abstract_inverted_index.literature	5
abstract_inverted_index.previously	32
abstract_inverted_index.proportion	234
abstract_inverted_index.<0.001),	143
abstract_inverted_index.<0.001).	154
abstract_inverted_index.Background:	0
abstract_inverted_index.activities,	194, 196
abstract_inverted_index.dependency,	201
abstract_inverted_index.depression.	170
abstract_inverted_index.functioning	145
abstract_inverted_index.instruments	34
abstract_inverted_index.significant	225
abstract_inverted_index.demonstrated	217
abstract_inverted_index.functioning,	198
abstract_inverted_index.difficulties,	200
abstract_inverted_index.significantly	176
abstract_inverted_index.questionnaires	82
abstract_inverted_index.study.Results:	97
abstract_inverted_index.syndrome.Methods:	39
abstract_inverted_index.vision.Conclusions:	213
cited_by_percentile_year.max	95
cited_by_percentile_year.min	91
countries_distinct_count	1
institutions_distinct_count	4
citation_normalized_percentile.value	0.04681913
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False