Assessment of in vitro cytotoxicity of saffron (Crocus sativus L.) on cervical cancer cells (HEp-2) and their in vivo pre-clinical toxicity in normal swiss albino mice Article Swipe
Hamid A. Bakshi
,
Faruck Lukmanul Hakkim
,
Smitha Sam
,
Mohammed Al-Buloshi
·
YOU?
·
· 2016
· Open Access
·
YOU?
·
· 2016
· Open Access
·
Cervical cancer is the second leading cause of death in women followed by breast cancer. Chemotherapy is the most feasible format to handle but their clinical consequences such as tumor relapse, drug resistance accompanied with severe toxicity is uncontrollable. Developing non-toxic chemo drug is major goal of cancer researchers. Medicinal herbs and plants remain as important source of drugs. In this study we explored in vitro anti-cancer potential of Crocus sativus (common name - Saffron) extract (CSE) on cervical cancer cells (HEp-2) and to study their in vivo toxicity profile in normal Swiss albino mice. HEp-2 and Vero cell viability was measured by MTT assay and morphology of cells was observed after 24 h of treatment of CSE (25, 50, 75 and 100 µg/ml). CSE elicit considerable dose-dependent cell death on HEp-2 cells whereas vero cells survived after 24 h of treatment. Further HEp-2 cells lost their adherence and morphology significantly after 24 h of treatment. In vivo toxicity profile by histological studies revealed no observable histopathologic differences in the liver, kidney, spleen, lungs and heart of CSE treated and untreated groups. Further we found that crocin is the principal component of CSE extract by high performance liquid chromatography (HPLC). Thus our present study compels us to continue to examine the effects of CSE on other human and murine neoplasms with the final goal of transforming this formulation to clinic. However, more detailed mechanistic studies are needed to fully delineate the role of C. sativus in cancer treatment.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdf
- OA Status
- green
- Cited By
- 7
- Related Works
- 20
- OpenAlex ID
- https://openalex.org/W2994314574
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2994314574Canonical identifier for this work in OpenAlex
- Title
-
Assessment of in vitro cytotoxicity of saffron (Crocus sativus L.) on cervical cancer cells (HEp-2) and their in vivo pre-clinical toxicity in normal swiss albino miceWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2016Year of publication
- Publication date
-
2016-09-01Full publication date if available
- Authors
-
Hamid A. Bakshi, Faruck Lukmanul Hakkim, Smitha Sam, Mohammed Al-BuloshiList of authors in order
- Landing page
-
https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdfPublisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdfDirect OA link when available
- Concepts
-
Crocus sativus, In vivo, Toxicity, Pharmacology, Medicine, Crocin, Cancer cell, Cancer, MTT assay, Cytotoxicity, Viability assay, In vitro, Traditional medicine, Biology, Internal medicine, Biochemistry, BiotechnologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
-
2024: 1, 2023: 1, 2022: 2, 2021: 1, 2020: 2Per-year citation counts (last 5 years)
- Related works (count)
-
20Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2994314574 |
|---|---|
| doi | |
| ids.mag | 2994314574 |
| ids.openalex | https://openalex.org/W2994314574 |
| fwci | 0.0 |
| type | article |
| title | Assessment of in vitro cytotoxicity of saffron (Crocus sativus L.) on cervical cancer cells (HEp-2) and their in vivo pre-clinical toxicity in normal swiss albino mice |
| biblio.issue | 5 |
| biblio.volume | 4 |
| biblio.last_page | 83 |
| biblio.first_page | 80 |
| topics[0].id | https://openalex.org/T12758 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9991000294685364 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2730 |
| topics[0].subfield.display_name | Oncology |
| topics[0].display_name | Saffron Plant Research Studies |
| topics[1].id | https://openalex.org/T13798 |
| topics[1].field.id | https://openalex.org/fields/30 |
| topics[1].field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| topics[1].score | 0.9096999764442444 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/3004 |
| topics[1].subfield.display_name | Pharmacology |
| topics[1].display_name | Hops Chemistry and Applications |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2779571273 |
| concepts[0].level | 2 |
| concepts[0].score | 0.891696572303772 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q15041677 |
| concepts[0].display_name | Crocus sativus |
| concepts[1].id | https://openalex.org/C207001950 |
| concepts[1].level | 2 |
| concepts[1].score | 0.6914045810699463 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q141124 |
| concepts[1].display_name | In vivo |
| concepts[2].id | https://openalex.org/C29730261 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6769978404045105 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q274160 |
| concepts[2].display_name | Toxicity |
| concepts[3].id | https://openalex.org/C98274493 |
| concepts[3].level | 1 |
| concepts[3].score | 0.6738840937614441 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q128406 |
| concepts[3].display_name | Pharmacology |
| concepts[4].id | https://openalex.org/C71924100 |
| concepts[4].level | 0 |
| concepts[4].score | 0.5839410424232483 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[4].display_name | Medicine |
| concepts[5].id | https://openalex.org/C2777637054 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5397461652755737 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q424767 |
| concepts[5].display_name | Crocin |
| concepts[6].id | https://openalex.org/C96232424 |
| concepts[6].level | 3 |
| concepts[6].score | 0.5181949734687805 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q4118072 |
| concepts[6].display_name | Cancer cell |
| concepts[7].id | https://openalex.org/C121608353 |
| concepts[7].level | 2 |
| concepts[7].score | 0.504613995552063 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q12078 |
| concepts[7].display_name | Cancer |
| concepts[8].id | https://openalex.org/C2780783641 |
| concepts[8].level | 3 |
| concepts[8].score | 0.4880346357822418 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q738686 |
| concepts[8].display_name | MTT assay |
| concepts[9].id | https://openalex.org/C109316439 |
| concepts[9].level | 3 |
| concepts[9].score | 0.4762984812259674 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q246181 |
| concepts[9].display_name | Cytotoxicity |
| concepts[10].id | https://openalex.org/C53227056 |
| concepts[10].level | 3 |
| concepts[10].score | 0.4745512902736664 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q189152 |
| concepts[10].display_name | Viability assay |
| concepts[11].id | https://openalex.org/C202751555 |
| concepts[11].level | 2 |
| concepts[11].score | 0.4300026595592499 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q221681 |
| concepts[11].display_name | In vitro |
| concepts[12].id | https://openalex.org/C556039675 |
| concepts[12].level | 1 |
| concepts[12].score | 0.3672279715538025 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q771035 |
| concepts[12].display_name | Traditional medicine |
| concepts[13].id | https://openalex.org/C86803240 |
| concepts[13].level | 0 |
| concepts[13].score | 0.28414905071258545 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[13].display_name | Biology |
| concepts[14].id | https://openalex.org/C126322002 |
| concepts[14].level | 1 |
| concepts[14].score | 0.21848416328430176 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[14].display_name | Internal medicine |
| concepts[15].id | https://openalex.org/C55493867 |
| concepts[15].level | 1 |
| concepts[15].score | 0.10364207625389099 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q7094 |
| concepts[15].display_name | Biochemistry |
| concepts[16].id | https://openalex.org/C150903083 |
| concepts[16].level | 1 |
| concepts[16].score | 0.0796210765838623 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q7108 |
| concepts[16].display_name | Biotechnology |
| keywords[0].id | https://openalex.org/keywords/crocus-sativus |
| keywords[0].score | 0.891696572303772 |
| keywords[0].display_name | Crocus sativus |
| keywords[1].id | https://openalex.org/keywords/in-vivo |
| keywords[1].score | 0.6914045810699463 |
| keywords[1].display_name | In vivo |
| keywords[2].id | https://openalex.org/keywords/toxicity |
| keywords[2].score | 0.6769978404045105 |
| keywords[2].display_name | Toxicity |
| keywords[3].id | https://openalex.org/keywords/pharmacology |
| keywords[3].score | 0.6738840937614441 |
| keywords[3].display_name | Pharmacology |
| keywords[4].id | https://openalex.org/keywords/medicine |
| keywords[4].score | 0.5839410424232483 |
| keywords[4].display_name | Medicine |
| keywords[5].id | https://openalex.org/keywords/crocin |
| keywords[5].score | 0.5397461652755737 |
| keywords[5].display_name | Crocin |
| keywords[6].id | https://openalex.org/keywords/cancer-cell |
| keywords[6].score | 0.5181949734687805 |
| keywords[6].display_name | Cancer cell |
| keywords[7].id | https://openalex.org/keywords/cancer |
| keywords[7].score | 0.504613995552063 |
| keywords[7].display_name | Cancer |
| keywords[8].id | https://openalex.org/keywords/mtt-assay |
| keywords[8].score | 0.4880346357822418 |
| keywords[8].display_name | MTT assay |
| keywords[9].id | https://openalex.org/keywords/cytotoxicity |
| keywords[9].score | 0.4762984812259674 |
| keywords[9].display_name | Cytotoxicity |
| keywords[10].id | https://openalex.org/keywords/viability-assay |
| keywords[10].score | 0.4745512902736664 |
| keywords[10].display_name | Viability assay |
| keywords[11].id | https://openalex.org/keywords/in-vitro |
| keywords[11].score | 0.4300026595592499 |
| keywords[11].display_name | In vitro |
| keywords[12].id | https://openalex.org/keywords/traditional-medicine |
| keywords[12].score | 0.3672279715538025 |
| keywords[12].display_name | Traditional medicine |
| keywords[13].id | https://openalex.org/keywords/biology |
| keywords[13].score | 0.28414905071258545 |
| keywords[13].display_name | Biology |
| keywords[14].id | https://openalex.org/keywords/internal-medicine |
| keywords[14].score | 0.21848416328430176 |
| keywords[14].display_name | Internal medicine |
| keywords[15].id | https://openalex.org/keywords/biochemistry |
| keywords[15].score | 0.10364207625389099 |
| keywords[15].display_name | Biochemistry |
| keywords[16].id | https://openalex.org/keywords/biotechnology |
| keywords[16].score | 0.0796210765838623 |
| keywords[16].display_name | Biotechnology |
| language | en |
| locations[0].id | mag:2994314574 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2764907976 |
| locations[0].source.issn | 2321-2187, 2394-0514 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2321-2187 |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | International Journal of Herbal Medicine |
| locations[0].source.host_organization | |
| locations[0].source.host_organization_name | |
| locations[0].source.host_organization_lineage | |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | |
| locations[0].raw_type | |
| locations[0].license_id | |
| locations[0].is_accepted | False |
| locations[0].is_published | |
| locations[0].raw_source_name | International Journal of Herbal Medicine |
| locations[0].landing_page_url | https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdf |
| authorships[0].author.id | https://openalex.org/A5087192033 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-1966-040X |
| authorships[0].author.display_name | Hamid A. Bakshi |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Hamid A Bakshi |
| authorships[0].is_corresponding | False |
| authorships[1].author.id | https://openalex.org/A5055905860 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-1194-0933 |
| authorships[1].author.display_name | Faruck Lukmanul Hakkim |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Faruck Lukmanul Hakkim |
| authorships[1].is_corresponding | False |
| authorships[2].author.id | https://openalex.org/A5048089786 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Smitha Sam |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Smitha Sam |
| authorships[2].is_corresponding | False |
| authorships[3].author.id | https://openalex.org/A5112312877 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Mohammed Al-Buloshi |
| authorships[3].author_position | last |
| authorships[3].raw_author_name | Mohammed Al-Buloshi |
| authorships[3].is_corresponding | False |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdf |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Assessment of in vitro cytotoxicity of saffron (Crocus sativus L.) on cervical cancer cells (HEp-2) and their in vivo pre-clinical toxicity in normal swiss albino mice |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-10-10T17:16:08.811792 |
| primary_topic.id | https://openalex.org/T12758 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9991000294685364 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2730 |
| primary_topic.subfield.display_name | Oncology |
| primary_topic.display_name | Saffron Plant Research Studies |
| related_works | https://openalex.org/W3185849219, https://openalex.org/W1973549682, https://openalex.org/W2591436937, https://openalex.org/W2896159864, https://openalex.org/W2318223889, https://openalex.org/W3080109216, https://openalex.org/W2581085714, https://openalex.org/W1976502905, https://openalex.org/W2069738834, https://openalex.org/W2093610198, https://openalex.org/W1487531210, https://openalex.org/W3191262649, https://openalex.org/W2906790449, https://openalex.org/W2035072754, https://openalex.org/W1997342881, https://openalex.org/W2042205314, https://openalex.org/W2018741186, https://openalex.org/W2020117567, https://openalex.org/W2080975286, https://openalex.org/W1963541683 |
| cited_by_count | 7 |
| counts_by_year[0].year | 2024 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 1 |
| counts_by_year[2].year | 2022 |
| counts_by_year[2].cited_by_count | 2 |
| counts_by_year[3].year | 2021 |
| counts_by_year[3].cited_by_count | 1 |
| counts_by_year[4].year | 2020 |
| counts_by_year[4].cited_by_count | 2 |
| locations_count | 1 |
| best_oa_location.id | mag:2994314574 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764907976 |
| best_oa_location.source.issn | 2321-2187, 2394-0514 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2321-2187 |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | International Journal of Herbal Medicine |
| best_oa_location.source.host_organization | |
| best_oa_location.source.host_organization_name | |
| best_oa_location.source.host_organization_lineage | |
| best_oa_location.license | |
| best_oa_location.pdf_url | |
| best_oa_location.version | |
| best_oa_location.raw_type | |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | International Journal of Herbal Medicine |
| best_oa_location.landing_page_url | https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdf |
| primary_location.id | mag:2994314574 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2764907976 |
| primary_location.source.issn | 2321-2187, 2394-0514 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2321-2187 |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | International Journal of Herbal Medicine |
| primary_location.source.host_organization | |
| primary_location.source.host_organization_name | |
| primary_location.source.host_organization_lineage | |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | |
| primary_location.raw_type | |
| primary_location.license_id | |
| primary_location.is_accepted | False |
| primary_location.is_published | False |
| primary_location.raw_source_name | International Journal of Herbal Medicine |
| primary_location.landing_page_url | https://www.florajournal.com/archives/2016/vol4issue5/PartB/4-6-12-643.pdf |
| publication_date | 2016-09-01 |
| publication_year | 2016 |
| referenced_works_count | 0 |
| abstract_inverted_index.- | 73 |
| abstract_inverted_index.h | 113, 139, 153 |
| abstract_inverted_index.24 | 112, 138, 152 |
| abstract_inverted_index.75 | 120 |
| abstract_inverted_index.C. | 243 |
| abstract_inverted_index.In | 59, 156 |
| abstract_inverted_index.as | 28, 54 |
| abstract_inverted_index.by | 12, 102, 160, 194 |
| abstract_inverted_index.in | 9, 64, 86, 90, 168, 245 |
| abstract_inverted_index.is | 2, 16, 37, 43, 187 |
| abstract_inverted_index.no | 164 |
| abstract_inverted_index.of | 7, 46, 57, 68, 107, 114, 116, 140, 154, 176, 191, 212, 224, 242 |
| abstract_inverted_index.on | 77, 130, 214 |
| abstract_inverted_index.to | 21, 83, 206, 208, 228, 237 |
| abstract_inverted_index.us | 205 |
| abstract_inverted_index.we | 62, 183 |
| abstract_inverted_index.100 | 122 |
| abstract_inverted_index.50, | 119 |
| abstract_inverted_index.CSE | 117, 124, 177, 192, 213 |
| abstract_inverted_index.MTT | 103 |
| abstract_inverted_index.and | 51, 82, 96, 105, 121, 148, 174, 179, 217 |
| abstract_inverted_index.are | 235 |
| abstract_inverted_index.but | 23 |
| abstract_inverted_index.our | 201 |
| abstract_inverted_index.the | 3, 17, 169, 188, 210, 221, 240 |
| abstract_inverted_index.was | 100, 109 |
| abstract_inverted_index.(25, | 118 |
| abstract_inverted_index.Thus | 200 |
| abstract_inverted_index.Vero | 97 |
| abstract_inverted_index.cell | 98, 128 |
| abstract_inverted_index.drug | 31, 42 |
| abstract_inverted_index.goal | 45, 223 |
| abstract_inverted_index.high | 195 |
| abstract_inverted_index.lost | 145 |
| abstract_inverted_index.more | 231 |
| abstract_inverted_index.most | 18 |
| abstract_inverted_index.name | 72 |
| abstract_inverted_index.role | 241 |
| abstract_inverted_index.such | 27 |
| abstract_inverted_index.that | 185 |
| abstract_inverted_index.this | 60, 226 |
| abstract_inverted_index.vero | 134 |
| abstract_inverted_index.vivo | 87, 157 |
| abstract_inverted_index.with | 34, 220 |
| abstract_inverted_index.(CSE) | 76 |
| abstract_inverted_index.HEp-2 | 95, 131, 143 |
| abstract_inverted_index.Swiss | 92 |
| abstract_inverted_index.after | 111, 137, 151 |
| abstract_inverted_index.assay | 104 |
| abstract_inverted_index.cause | 6 |
| abstract_inverted_index.cells | 80, 108, 132, 135, 144 |
| abstract_inverted_index.chemo | 41 |
| abstract_inverted_index.death | 8, 129 |
| abstract_inverted_index.final | 222 |
| abstract_inverted_index.found | 184 |
| abstract_inverted_index.fully | 238 |
| abstract_inverted_index.heart | 175 |
| abstract_inverted_index.herbs | 50 |
| abstract_inverted_index.human | 216 |
| abstract_inverted_index.lungs | 173 |
| abstract_inverted_index.major | 44 |
| abstract_inverted_index.mice. | 94 |
| abstract_inverted_index.other | 215 |
| abstract_inverted_index.study | 61, 84, 203 |
| abstract_inverted_index.their | 24, 85, 146 |
| abstract_inverted_index.tumor | 29 |
| abstract_inverted_index.vitro | 65 |
| abstract_inverted_index.women | 10 |
| abstract_inverted_index.Crocus | 69 |
| abstract_inverted_index.albino | 93 |
| abstract_inverted_index.breast | 13 |
| abstract_inverted_index.cancer | 1, 47, 79, 246 |
| abstract_inverted_index.crocin | 186 |
| abstract_inverted_index.drugs. | 58 |
| abstract_inverted_index.elicit | 125 |
| abstract_inverted_index.format | 20 |
| abstract_inverted_index.handle | 22 |
| abstract_inverted_index.liquid | 197 |
| abstract_inverted_index.liver, | 170 |
| abstract_inverted_index.murine | 218 |
| abstract_inverted_index.needed | 236 |
| abstract_inverted_index.normal | 91 |
| abstract_inverted_index.plants | 52 |
| abstract_inverted_index.remain | 53 |
| abstract_inverted_index.second | 4 |
| abstract_inverted_index.severe | 35 |
| abstract_inverted_index.source | 56 |
| abstract_inverted_index.(HEp-2) | 81 |
| abstract_inverted_index.(HPLC). | 199 |
| abstract_inverted_index.(common | 71 |
| abstract_inverted_index.Further | 142, 182 |
| abstract_inverted_index.cancer. | 14 |
| abstract_inverted_index.clinic. | 229 |
| abstract_inverted_index.compels | 204 |
| abstract_inverted_index.effects | 211 |
| abstract_inverted_index.examine | 209 |
| abstract_inverted_index.extract | 75, 193 |
| abstract_inverted_index.groups. | 181 |
| abstract_inverted_index.kidney, | 171 |
| abstract_inverted_index.leading | 5 |
| abstract_inverted_index.present | 202 |
| abstract_inverted_index.profile | 89, 159 |
| abstract_inverted_index.sativus | 70, 244 |
| abstract_inverted_index.spleen, | 172 |
| abstract_inverted_index.studies | 162, 234 |
| abstract_inverted_index.treated | 178 |
| abstract_inverted_index.whereas | 133 |
| abstract_inverted_index.Cervical | 0 |
| abstract_inverted_index.However, | 230 |
| abstract_inverted_index.Saffron) | 74 |
| abstract_inverted_index.cervical | 78 |
| abstract_inverted_index.clinical | 25 |
| abstract_inverted_index.continue | 207 |
| abstract_inverted_index.detailed | 232 |
| abstract_inverted_index.explored | 63 |
| abstract_inverted_index.feasible | 19 |
| abstract_inverted_index.followed | 11 |
| abstract_inverted_index.measured | 101 |
| abstract_inverted_index.observed | 110 |
| abstract_inverted_index.relapse, | 30 |
| abstract_inverted_index.revealed | 163 |
| abstract_inverted_index.survived | 136 |
| abstract_inverted_index.toxicity | 36, 88, 158 |
| abstract_inverted_index.µg/ml). | 123 |
| abstract_inverted_index.Medicinal | 49 |
| abstract_inverted_index.adherence | 147 |
| abstract_inverted_index.component | 190 |
| abstract_inverted_index.delineate | 239 |
| abstract_inverted_index.important | 55 |
| abstract_inverted_index.neoplasms | 219 |
| abstract_inverted_index.non-toxic | 40 |
| abstract_inverted_index.potential | 67 |
| abstract_inverted_index.principal | 189 |
| abstract_inverted_index.treatment | 115 |
| abstract_inverted_index.untreated | 180 |
| abstract_inverted_index.viability | 99 |
| abstract_inverted_index.Developing | 39 |
| abstract_inverted_index.morphology | 106, 149 |
| abstract_inverted_index.observable | 165 |
| abstract_inverted_index.resistance | 32 |
| abstract_inverted_index.treatment. | 141, 155, 247 |
| abstract_inverted_index.accompanied | 33 |
| abstract_inverted_index.anti-cancer | 66 |
| abstract_inverted_index.differences | 167 |
| abstract_inverted_index.formulation | 227 |
| abstract_inverted_index.mechanistic | 233 |
| abstract_inverted_index.performance | 196 |
| abstract_inverted_index.Chemotherapy | 15 |
| abstract_inverted_index.consequences | 26 |
| abstract_inverted_index.considerable | 126 |
| abstract_inverted_index.histological | 161 |
| abstract_inverted_index.researchers. | 48 |
| abstract_inverted_index.transforming | 225 |
| abstract_inverted_index.significantly | 150 |
| abstract_inverted_index.chromatography | 198 |
| abstract_inverted_index.dose-dependent | 127 |
| abstract_inverted_index.histopathologic | 166 |
| abstract_inverted_index.uncontrollable. | 38 |
| cited_by_percentile_year.max | 96 |
| cited_by_percentile_year.min | 89 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 4 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8700000047683716 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.26541493 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |