Assessment of Intramural Segment Compression in Anomalous Coronary Arteries through Patient-Specific Finite Element Modeling Article Swipe
Antonio Rosato
,
Mauro Lo Rito
,
Serena Anglese
,
Valentina Ceserani
,
Ariel Pascaner
,
Francesco Secchi
,
Michele Conti
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.10559760
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.10559760
Rosato A, Lo Rito M, Anglese S, Ceserani V, Pascaner AF, Secchi F, Conti M. Assessment of Intramural Segment Compression in Anomalous Coronary Arteries through Patient-Specific Finite Element Modeling. Applied Sciences. 2023; 13(20):11185. https://doi.org/10.3390/app132011185 Abstract Background: Anomalous Aortic Origin of a Coronary Artery (AAOCA) is a congenital condition that can lead to ischemia and sudden cardiac death. Current diagnostic tools are unable to fully quantify the pathological behavior that occurs mainly with physical effort. Methods: Patients’ computed tomography scans and centerline-based geometric quantities were used to develop three-dimensional computer-aided design models of the main anatomical variants of AAOCA. Blood pressure ranging from rest to extreme effort was simulated through structural finite element analyses, and the pressurized geometries were analyzed to evaluate coronary lumen cross-sectional areas and variations at the different loading conditions. Results: We simulated 39 subjects, demonstrating the ability to reproduce accurately the patient-specific anatomy of different AAOCA variants and capture pathological behaviors. AAOCAs with intramural courses showed compression along the proximal segment with a caliber reduction ranging from 0.14% to 18.87% at different pressure levels. The percentage of proximal narrowing relative to the distal segment was greater than any other type of anomalous course and exceeded 50% with simulated exertion. Conclusions: The present study proposes a computational pipeline to investigate conditions not reproducible in clinical practice, providing information to support decision-making in the management of AAOCA patients.
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- OA Status
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All OpenAlex metadata
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https://openalex.org/W4393659918Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5281/zenodo.10559760Digital Object Identifier
- Title
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Assessment of Intramural Segment Compression in Anomalous Coronary Arteries through Patient-Specific Finite Element ModelingWork title
- Type
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datasetOpenAlex work type
- Language
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enPrimary language
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2024Year of publication
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2024-01-24Full publication date if available
- Authors
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Antonio Rosato, Mauro Lo Rito, Serena Anglese, Valentina Ceserani, Ariel Pascaner, Francesco Secchi, Michele ContiList of authors in order
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https://doi.org/10.5281/zenodo.10559760Publisher landing page
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
- OA URL
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https://doi.org/10.5281/zenodo.10559760Direct OA link when available
- Concepts
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Coronary arteries, Finite element method, Compression (physics), Cardiology, Internal medicine, Medicine, Geology, Materials science, Structural engineering, Engineering, Artery, Composite materialTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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