Association between Body Weight Gain from 20 Years of Age and Diabetic Nephropathy in Japanese Patients with Type 2 Diabetes Article Swipe
Hiroshi Okada
,
Muhei Tanaka
,
Goji Hasegawa
,
Hanako Nakajima
,
Mayuko Kadono
,
Tomoki Miyoshi
,
Yuki Okada
,
Koji Nakano
,
Tetsuro Yamane
,
Michiaki Fukui
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1159/000500722
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.1159/000500722
Background/Aims: It has been reported that the body mass index shows a U-shaped association with death from cardiovascular disease (CVD) in the Asian population. The relationship between body weight (BW) gain from early adulthood and diabetic nephropathy remains to be elucidated in Japanese patients with type 2 diabetes. Our aim was to investigate the association between BW gain from early adulthood and diabetic nephropathy in Japanese patients with type 2 diabetes. Methods: We assessed the BW of 471 consecutive patients with type 2 diabetes and calculated the change in BW from the age of 20 years to the lifetime maximum (ΔBWmax-20y). We then evaluated the relationship of ΔBWmax-20y with the degree of urinary albumin excretion (UAE), which is a useful marker for CVD. Results: ΔBWmax-20y negatively correlated with the logarithm of UAE (r = –0.160, p = 0.002). Multiple regression analysis demonstrated that ΔBWmax-20y was independently correlated with the logarithm of UAE (β =–0.112, p =0.034). Conclusions: BW gain from the age of 20 years is correlated with diabetic nephropathy in Japanese patients with type 2 diabetes.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1159/000500722
- OA Status
- gold
- Cited By
- 1
- References
- 24
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2953597617
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2953597617Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1159/000500722Digital Object Identifier
- Title
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Association between Body Weight Gain from 20 Years of Age and Diabetic Nephropathy in Japanese Patients with Type 2 DiabetesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2019Year of publication
- Publication date
-
2019-01-01Full publication date if available
- Authors
-
Hiroshi Okada, Muhei Tanaka, Goji Hasegawa, Hanako Nakajima, Mayuko Kadono, Tomoki Miyoshi, Yuki Okada, Koji Nakano, Tetsuro Yamane, Michiaki FukuiList of authors in order
- Landing page
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https://doi.org/10.1159/000500722Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1159/000500722Direct OA link when available
- Concepts
-
Medicine, Internal medicine, Diabetes mellitus, Diabetic nephropathy, Weight gain, Body mass index, Type 2 diabetes, Endocrinology, Nephropathy, Type 2 Diabetes Mellitus, Body weightTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
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2024: 1Per-year citation counts (last 5 years)
- References (count)
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10Other works algorithmically related by OpenAlex
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