ISEE Conference Abstracts • Vol 2020 • No 1
Association of childhood neighborhood disadvantage with young adult DNA methylation
October 2020 • Aaron Reuben, Karen Sugden, Louise Arsenault, David L. Corcoran, Andrea Danese, Helen L. Fisher, Terrie E. Moffitt, Joanne B. Newbury, Candice L. Odg…
Importance: DNA methylation has been proposed as an epigenetic mechanism by which the childhood neighborhood environment may influence the genome to compromise adult health.Objective: To determine whether childhood neighborhood disadvantage is associated with differences in DNA methylation by age 18 years.Design: Longitudinal-prospective study of a 1994-95 birth cohort, followed to age 18 years (until September, 2014; 93% retention). Data analysis was performed from March to June 2019.Setting: United Kingdom. Part…