Association of maternal mineral status with the risk of preterm birth: a retrospective cohort study Article Swipe
YOU?
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· 2024
· Open Access
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· DOI: https://doi.org/10.3389/fnut.2024.1329720
Background There has been a gradual increase in the proportion of preterm birth in China during the past several decades. Maternal malnutrition is a significant determinant for preterm birth. Nevertheless, comprehensive studies investigating serum mineral levels during pregnancy associated with preterm birth remain scarce. This study aims to assess the associations between maternal serum mineral levels and the risk of preterm birth. Methods This retrospective cohort study of 18,048 pregnant women used data from a tertiary hospital in China from January 2016 to December 2022. Demographic data and serum mineral concentrations in the second and third trimesters of mothers were collected from the hospital information system. Analysis was performed using restricted cubic splines and logistic regression models. Results The proportion of preterm birth in this study was 6.01%. Phosphorus [P for overall = 0.005; P for nonlinear = 0.490; OR (95%CI) = 1.11 (1.04, 1.18)] and chlorine [P for overall = 0.002; P for nonlinear = 0.058; OR (95%CI) = 1.11 (1.03, 1.19)] showed a significant positive correlation with preterm birth in a linear fashion. Furthermore, serum levels of potassium (P for nonlinear <0.001), sodium (P for nonlinear = 0.004), and magnesium (P for nonlinear <0.001) exhibited non-linear relationships with the risk of preterm birth. Conclusion Serum levels of some minerals during pregnancy were associated with the risk of preterm birth among pregnant women. In addition to commonly recognized micronutrients such as folic acid, iron, and vitamin D, healthcare providers should also pay attention to the levels of these minerals during pregnancy.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fnut.2024.1329720
- https://www.frontiersin.org/articles/10.3389/fnut.2024.1329720/pdf?isPublishedV2=False
- OA Status
- gold
- Cited By
- 1
- References
- 48
- Related Works
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- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4396793689Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fnut.2024.1329720Digital Object Identifier
- Title
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Association of maternal mineral status with the risk of preterm birth: a retrospective cohort studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
-
2024-05-10Full publication date if available
- Authors
-
Sumiao Hong, Nan Jiang, Guankai Lin, Quqing Wang, Xiaoyang Xu, Xinrui Shi, You Zhou, Xiaoting Wen, Sun Bao-chang, Hexing Wang, Min Huang, Jiwei Wang, Na Wang, Yue Chen, Qingwu JiangList of authors in order
- Landing page
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https://doi.org/10.3389/fnut.2024.1329720Publisher landing page
- PDF URL
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https://www.frontiersin.org/articles/10.3389/fnut.2024.1329720/pdf?isPublishedV2=FalseDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/articles/10.3389/fnut.2024.1329720/pdf?isPublishedV2=FalseDirect OA link when available
- Concepts
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Medicine, Obstetrics, Pregnancy, Retrospective cohort study, Cohort study, Micronutrient, Cohort, Internal medicine, Biology, Genetics, PathologyTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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48Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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