Association of Polypharmacy and Health-Related Quality of Life Among US Adults: A Cross-Sectional Analysis of the 2022 MEPS Data Article Swipe
Sreelatha Akkala
,
Meesha Iqbal
,
Regina Hansen
,
Jyothi Akkula
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/jal5040052
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3390/jal5040052
Polypharmacy is common among aging populations and is associated with adverse health outcomes. We designed this cross-sectional study to determine the association of polypharmacy with physical and mental health-related quality of life (HRQoL) among the United States (US) adults aged ≥50 years. We used the nationally representative Medical Expenditure Panel Survey (MEPS) data, 2022, and conducted the analysis on 5343 adults. Polypharmacy was operationalized as the use of five or more medications simultaneously. HRQoL was assessed via physical and mental component summary scores from the 12-item short form health survey. We applied a multivariate linear regression model to determine the relationship between polypharmacy and HRQoL, after adjusting for sociodemographic factors (age, sex, race/ethnicity, and marital status) and comorbidities (diabetes and cardiovascular disease). Polypharmacy was reported by 70% of participants and was significantly associated with decreased physical (adjusted β: −2.95, 95% confidence interval [CI]: −3.64, −2.26, R2 = 0.25, p < 0.001) and mental HRQoL (adjusted β: −0.85, 95% CI: −1.48, −0.22, R2 = 0.07, p < 0.001). Other significant predictors of poor HRQoL included female sex, unmarried status, public insurance, lower educational attainment, and higher comorbidity index (p < 0.001). In contrast, higher education and private insurance were associated with better HRQoL. Based on the study findings, it is crucial to invest in programs and targeted interventions such as routine medication review and deprescribing strategies to reduce the negative impact of polypharmacy on HRQoL among US adults.
Related Topics
Concepts
Polypharmacy
Medicine
Medical Expenditure Panel Survey
Quality of life (healthcare)
Marital status
Psychological intervention
Gerontology
Comorbidity
Mental health
Deprescribing
Multivariate analysis
Confidence interval
Life expectancy
Cross-sectional study
National Health and Nutrition Examination Survey
Association (psychology)
Bayesian multivariate linear regression
Psychiatry
Public health
Discontinuation
Odds ratio
Environmental health
Population
Adverse effect
Activities of daily living
Mental illness
MEDLINE
Bivariate analysis
Multimorbidity
Odds
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/jal5040052
- OA Status
- diamond
- References
- 22
- OpenAlex ID
- https://openalex.org/W7106168344
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W7106168344Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/jal5040052Digital Object Identifier
- Title
-
Association of Polypharmacy and Health-Related Quality of Life Among US Adults: A Cross-Sectional Analysis of the 2022 MEPS DataWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-11-20Full publication date if available
- Authors
-
Sreelatha Akkala, Meesha Iqbal, Regina Hansen, Jyothi AkkulaList of authors in order
- Landing page
-
https://doi.org/10.3390/jal5040052Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.3390/jal5040052Direct OA link when available
- Concepts
-
Polypharmacy, Medicine, Medical Expenditure Panel Survey, Quality of life (healthcare), Marital status, Psychological intervention, Gerontology, Comorbidity, Mental health, Deprescribing, Multivariate analysis, Confidence interval, Life expectancy, Cross-sectional study, National Health and Nutrition Examination Survey, Association (psychology), Bayesian multivariate linear regression, Psychiatry, Public health, Discontinuation, Odds ratio, Environmental health, Population, Adverse effect, Activities of daily living, Mental illness, MEDLINE, Bivariate analysis, Multimorbidity, OddsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
22Number of works referenced by this work
Full payload
| id | https://openalex.org/W7106168344 |
|---|---|
| doi | https://doi.org/10.3390/jal5040052 |
| ids.doi | https://doi.org/10.3390/jal5040052 |
| ids.openalex | https://openalex.org/W7106168344 |
| fwci | 0.0 |
| type | article |
| title | Association of Polypharmacy and Health-Related Quality of Life Among US Adults: A Cross-Sectional Analysis of the 2022 MEPS Data |
| biblio.issue | 4 |
| biblio.volume | 5 |
| biblio.last_page | 52 |
| biblio.first_page | 52 |
| topics[0].id | https://openalex.org/T10496 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.8994579911231995 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2717 |
| topics[0].subfield.display_name | Geriatrics and Gerontology |
| topics[0].display_name | Pharmaceutical Practices and Patient Outcomes |
| topics[1].id | https://openalex.org/T11620 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.03282395750284195 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2714 |
| topics[1].subfield.display_name | Family Practice |
| topics[1].display_name | Medication Adherence and Compliance |
| topics[2].id | https://openalex.org/T11943 |
| topics[2].field.id | https://openalex.org/fields/30 |
| topics[2].field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| topics[2].score | 0.009495703503489494 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/3005 |
| topics[2].subfield.display_name | Toxicology |
| topics[2].display_name | Pharmacovigilance and Adverse Drug Reactions |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C36434225 |
| concepts[0].level | 2 |
| concepts[0].score | 0.9385167360305786 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1895998 |
| concepts[0].display_name | Polypharmacy |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.7672675848007202 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2780777579 |
| concepts[2].level | 4 |
| concepts[2].score | 0.7549350261688232 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q6806347 |
| concepts[2].display_name | Medical Expenditure Panel Survey |
| concepts[3].id | https://openalex.org/C2779951463 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6442747712135315 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q7268788 |
| concepts[3].display_name | Quality of life (healthcare) |
| concepts[4].id | https://openalex.org/C2781354955 |
| concepts[4].level | 3 |
| concepts[4].score | 0.621695876121521 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11920938 |
| concepts[4].display_name | Marital status |
| concepts[5].id | https://openalex.org/C27415008 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5415089726448059 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q7256382 |
| concepts[5].display_name | Psychological intervention |
| concepts[6].id | https://openalex.org/C74909509 |
| concepts[6].level | 1 |
| concepts[6].score | 0.5251854658126831 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q10387 |
| concepts[6].display_name | Gerontology |
| concepts[7].id | https://openalex.org/C2779159551 |
| concepts[7].level | 2 |
| concepts[7].score | 0.49217385053634644 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1414874 |
| concepts[7].display_name | Comorbidity |
| concepts[8].id | https://openalex.org/C134362201 |
| concepts[8].level | 2 |
| concepts[8].score | 0.4532986879348755 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q317309 |
| concepts[8].display_name | Mental health |
| concepts[9].id | https://openalex.org/C2776484012 |
| concepts[9].level | 3 |
| concepts[9].score | 0.41618242859840393 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q16251540 |
| concepts[9].display_name | Deprescribing |
| concepts[10].id | https://openalex.org/C38180746 |
| concepts[10].level | 2 |
| concepts[10].score | 0.4076441824436188 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q1952580 |
| concepts[10].display_name | Multivariate analysis |
| concepts[11].id | https://openalex.org/C44249647 |
| concepts[11].level | 2 |
| concepts[11].score | 0.40388593077659607 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q208498 |
| concepts[11].display_name | Confidence interval |
| concepts[12].id | https://openalex.org/C133925201 |
| concepts[12].level | 3 |
| concepts[12].score | 0.3681427836418152 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q188419 |
| concepts[12].display_name | Life expectancy |
| concepts[13].id | https://openalex.org/C142052008 |
| concepts[13].level | 2 |
| concepts[13].score | 0.35817238688468933 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q954027 |
| concepts[13].display_name | Cross-sectional study |
| concepts[14].id | https://openalex.org/C2779874844 |
| concepts[14].level | 3 |
| concepts[14].score | 0.3492386043071747 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q1967281 |
| concepts[14].display_name | National Health and Nutrition Examination Survey |
| concepts[15].id | https://openalex.org/C142853389 |
| concepts[15].level | 2 |
| concepts[15].score | 0.33261680603027344 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q744778 |
| concepts[15].display_name | Association (psychology) |
| concepts[16].id | https://openalex.org/C64946054 |
| concepts[16].level | 3 |
| concepts[16].score | 0.3256208598613739 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q4874476 |
| concepts[16].display_name | Bayesian multivariate linear regression |
| concepts[17].id | https://openalex.org/C118552586 |
| concepts[17].level | 1 |
| concepts[17].score | 0.3245520293712616 |
| concepts[17].wikidata | https://www.wikidata.org/wiki/Q7867 |
| concepts[17].display_name | Psychiatry |
| concepts[18].id | https://openalex.org/C138816342 |
| concepts[18].level | 2 |
| concepts[18].score | 0.3142998516559601 |
| concepts[18].wikidata | https://www.wikidata.org/wiki/Q189603 |
| concepts[18].display_name | Public health |
| concepts[19].id | https://openalex.org/C2778715236 |
| concepts[19].level | 2 |
| concepts[19].score | 0.30781710147857666 |
| concepts[19].wikidata | https://www.wikidata.org/wiki/Q55622662 |
| concepts[19].display_name | Discontinuation |
| concepts[20].id | https://openalex.org/C156957248 |
| concepts[20].level | 2 |
| concepts[20].score | 0.2969558537006378 |
| concepts[20].wikidata | https://www.wikidata.org/wiki/Q1862216 |
| concepts[20].display_name | Odds ratio |
| concepts[21].id | https://openalex.org/C99454951 |
| concepts[21].level | 1 |
| concepts[21].score | 0.29184383153915405 |
| concepts[21].wikidata | https://www.wikidata.org/wiki/Q932068 |
| concepts[21].display_name | Environmental health |
| concepts[22].id | https://openalex.org/C2908647359 |
| concepts[22].level | 2 |
| concepts[22].score | 0.2833888530731201 |
| concepts[22].wikidata | https://www.wikidata.org/wiki/Q2625603 |
| concepts[22].display_name | Population |
| concepts[23].id | https://openalex.org/C197934379 |
| concepts[23].level | 2 |
| concepts[23].score | 0.2728089988231659 |
| concepts[23].wikidata | https://www.wikidata.org/wiki/Q2047938 |
| concepts[23].display_name | Adverse effect |
| concepts[24].id | https://openalex.org/C79544238 |
| concepts[24].level | 2 |
| concepts[24].score | 0.2677743136882782 |
| concepts[24].wikidata | https://www.wikidata.org/wiki/Q423243 |
| concepts[24].display_name | Activities of daily living |
| concepts[25].id | https://openalex.org/C2776674806 |
| concepts[25].level | 3 |
| concepts[25].score | 0.264123797416687 |
| concepts[25].wikidata | https://www.wikidata.org/wiki/Q12135 |
| concepts[25].display_name | Mental illness |
| concepts[26].id | https://openalex.org/C2779473830 |
| concepts[26].level | 2 |
| concepts[26].score | 0.2635094225406647 |
| concepts[26].wikidata | https://www.wikidata.org/wiki/Q1540899 |
| concepts[26].display_name | MEDLINE |
| concepts[27].id | https://openalex.org/C64341305 |
| concepts[27].level | 2 |
| concepts[27].score | 0.2631935775279999 |
| concepts[27].wikidata | https://www.wikidata.org/wiki/Q4919225 |
| concepts[27].display_name | Bivariate analysis |
| concepts[28].id | https://openalex.org/C2909273474 |
| concepts[28].level | 3 |
| concepts[28].score | 0.26003915071487427 |
| concepts[28].wikidata | https://www.wikidata.org/wiki/Q1952420 |
| concepts[28].display_name | Multimorbidity |
| concepts[29].id | https://openalex.org/C143095724 |
| concepts[29].level | 3 |
| concepts[29].score | 0.25632134079933167 |
| concepts[29].wikidata | https://www.wikidata.org/wiki/Q515895 |
| concepts[29].display_name | Odds |
| keywords[0].id | https://openalex.org/keywords/polypharmacy |
| keywords[0].score | 0.9385167360305786 |
| keywords[0].display_name | Polypharmacy |
| keywords[1].id | https://openalex.org/keywords/medical-expenditure-panel-survey |
| keywords[1].score | 0.7549350261688232 |
| keywords[1].display_name | Medical Expenditure Panel Survey |
| keywords[2].id | https://openalex.org/keywords/quality-of-life |
| keywords[2].score | 0.6442747712135315 |
| keywords[2].display_name | Quality of life (healthcare) |
| keywords[3].id | https://openalex.org/keywords/marital-status |
| keywords[3].score | 0.621695876121521 |
| keywords[3].display_name | Marital status |
| keywords[4].id | https://openalex.org/keywords/psychological-intervention |
| keywords[4].score | 0.5415089726448059 |
| keywords[4].display_name | Psychological intervention |
| keywords[5].id | https://openalex.org/keywords/comorbidity |
| keywords[5].score | 0.49217385053634644 |
| keywords[5].display_name | Comorbidity |
| keywords[6].id | https://openalex.org/keywords/mental-health |
| keywords[6].score | 0.4532986879348755 |
| keywords[6].display_name | Mental health |
| keywords[7].id | https://openalex.org/keywords/deprescribing |
| keywords[7].score | 0.41618242859840393 |
| keywords[7].display_name | Deprescribing |
| keywords[8].id | https://openalex.org/keywords/multivariate-analysis |
| keywords[8].score | 0.4076441824436188 |
| keywords[8].display_name | Multivariate analysis |
| language | en |
| locations[0].id | doi:10.3390/jal5040052 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210180576 |
| locations[0].source.issn | 2673-9259 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2673-9259 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Journal of Ageing and Longevity |
| locations[0].source.host_organization | |
| locations[0].source.host_organization_name | |
| locations[0].source.host_organization_lineage | |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Ageing and Longevity |
| locations[0].landing_page_url | https://doi.org/10.3390/jal5040052 |
| indexed_in | crossref, doaj |
| authorships[0].author.id | https://openalex.org/A3085262504 |
| authorships[0].author.orcid | https://orcid.org/0000-0003-4061-9839 |
| authorships[0].author.display_name | Sreelatha Akkala |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[0].affiliations[0].raw_affiliation_string | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[0].institutions[0].id | https://openalex.org/I919571938 |
| authorships[0].institutions[0].ror | https://ror.org/https://ror.org/03gds6c39 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Sreelatha Akkala |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[1].author.id | https://openalex.org/A2802135334 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-3760-3414 |
| authorships[1].author.display_name | Meesha Iqbal |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[1].affiliations[0].raw_affiliation_string | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[1].institutions[0].id | https://openalex.org/I919571938 |
| authorships[1].institutions[0].ror | https://ror.org/https://ror.org/03gds6c39 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Meesha Iqbal |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[2].author.id | https://openalex.org/A2132245954 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-2259-3041 |
| authorships[2].author.display_name | Regina Hansen |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I919571938 |
| authorships[2].affiliations[0].raw_affiliation_string | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[2].institutions[0].id | https://openalex.org/I919571938 |
| authorships[2].institutions[0].ror | https://ror.org/https://ror.org/03gds6c39 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I919571938 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | The University of Texas Health Science Center at Houston |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Regina Hansen |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA |
| authorships[3].author.id | https://openalex.org/A5117505798 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Jyothi Akkula |
| authorships[3].countries | GB |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210164339 |
| authorships[3].affiliations[0].raw_affiliation_string | Independent Researcher, Hyderabad 500032, India |
| authorships[3].institutions[0].id | https://openalex.org/I4210164339 |
| authorships[3].institutions[0].ror | https://ror.org/https://ror.org/05cxzzq07 |
| authorships[3].institutions[0].type | government |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210164339 |
| authorships[3].institutions[0].country_code | GB |
| authorships[3].institutions[0].display_name | Oldham Council |
| authorships[3].author_position | last |
| authorships[3].raw_author_name | Jyothi Akkula |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Independent Researcher, Hyderabad 500032, India |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.3390/jal5040052 |
| open_access.oa_status | diamond |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-11-20T00:00:00 |
| display_name | Association of Polypharmacy and Health-Related Quality of Life Among US Adults: A Cross-Sectional Analysis of the 2022 MEPS Data |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-23T05:10:03.516525 |
| primary_topic.id | https://openalex.org/T10496 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.8994579911231995 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2717 |
| primary_topic.subfield.display_name | Geriatrics and Gerontology |
| primary_topic.display_name | Pharmaceutical Practices and Patient Outcomes |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.3390/jal5040052 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210180576 |
| best_oa_location.source.issn | 2673-9259 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2673-9259 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Journal of Ageing and Longevity |
| best_oa_location.source.host_organization | |
| best_oa_location.source.host_organization_name | |
| best_oa_location.source.host_organization_lineage | |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Ageing and Longevity |
| best_oa_location.landing_page_url | https://doi.org/10.3390/jal5040052 |
| primary_location.id | doi:10.3390/jal5040052 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210180576 |
| primary_location.source.issn | 2673-9259 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2673-9259 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Journal of Ageing and Longevity |
| primary_location.source.host_organization | |
| primary_location.source.host_organization_name | |
| primary_location.source.host_organization_lineage | |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Ageing and Longevity |
| primary_location.landing_page_url | https://doi.org/10.3390/jal5040052 |
| publication_date | 2025-11-20 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W4394029419, https://openalex.org/W2773711501, https://openalex.org/W4402713432, https://openalex.org/W3121955445, https://openalex.org/W4316877174, https://openalex.org/W2763920048, https://openalex.org/W4383896890, https://openalex.org/W3135197215, https://openalex.org/W4295425518, https://openalex.org/W4200118001, https://openalex.org/W4408699637, https://openalex.org/W2519234227, https://openalex.org/W4317869951, https://openalex.org/W4411736919, https://openalex.org/W2755450470, https://openalex.org/W4210908626, https://openalex.org/W2083817955, https://openalex.org/W4387844611, https://openalex.org/W2264220972, https://openalex.org/W4327813959, https://openalex.org/W4318457342, https://openalex.org/W4389052141 |
| referenced_works_count | 22 |
| abstract_inverted_index.= | 146, 162 |
| abstract_inverted_index.a | 92 |
| abstract_inverted_index.p | 148, 164 |
| abstract_inverted_index.(p | 187 |
| abstract_inverted_index.In | 190 |
| abstract_inverted_index.R2 | 145, 161 |
| abstract_inverted_index.US | 235 |
| abstract_inverted_index.We | 13, 42, 90 |
| abstract_inverted_index.as | 64, 218 |
| abstract_inverted_index.by | 125 |
| abstract_inverted_index.in | 212 |
| abstract_inverted_index.is | 1, 7, 208 |
| abstract_inverted_index.it | 207 |
| abstract_inverted_index.of | 22, 30, 67, 127, 170, 230 |
| abstract_inverted_index.on | 58, 203, 232 |
| abstract_inverted_index.or | 69 |
| abstract_inverted_index.to | 18, 97, 210, 225 |
| abstract_inverted_index.70% | 126 |
| abstract_inverted_index.95% | 139, 157 |
| abstract_inverted_index.CI: | 158 |
| abstract_inverted_index.and | 6, 26, 54, 78, 103, 113, 116, 119, 129, 151, 183, 194, 214, 222 |
| abstract_inverted_index.for | 107 |
| abstract_inverted_index.the | 20, 34, 44, 56, 65, 84, 99, 204, 227 |
| abstract_inverted_index.use | 66 |
| abstract_inverted_index.via | 76 |
| abstract_inverted_index.was | 62, 74, 123, 130 |
| abstract_inverted_index.β: | 137, 155 |
| abstract_inverted_index.< | 149, 165, 188 |
| abstract_inverted_index.(US) | 37 |
| abstract_inverted_index.5343 | 59 |
| abstract_inverted_index.aged | 39 |
| abstract_inverted_index.five | 68 |
| abstract_inverted_index.form | 87 |
| abstract_inverted_index.from | 83 |
| abstract_inverted_index.life | 31 |
| abstract_inverted_index.more | 70 |
| abstract_inverted_index.poor | 171 |
| abstract_inverted_index.sex, | 111, 175 |
| abstract_inverted_index.such | 217 |
| abstract_inverted_index.this | 15 |
| abstract_inverted_index.used | 43 |
| abstract_inverted_index.were | 197 |
| abstract_inverted_index.with | 9, 24, 133, 199 |
| abstract_inverted_index.(age, | 110 |
| abstract_inverted_index.0.07, | 163 |
| abstract_inverted_index.0.25, | 147 |
| abstract_inverted_index.2022, | 53 |
| abstract_inverted_index.Based | 202 |
| abstract_inverted_index.HRQoL | 73, 153, 172, 233 |
| abstract_inverted_index.Other | 167 |
| abstract_inverted_index.Panel | 49 |
| abstract_inverted_index.[CI]: | 142 |
| abstract_inverted_index.after | 105 |
| abstract_inverted_index.aging | 4 |
| abstract_inverted_index.among | 3, 33, 234 |
| abstract_inverted_index.data, | 52 |
| abstract_inverted_index.index | 186 |
| abstract_inverted_index.lower | 180 |
| abstract_inverted_index.model | 96 |
| abstract_inverted_index.short | 86 |
| abstract_inverted_index.study | 17, 205 |
| abstract_inverted_index.≥50 | 40 |
| abstract_inverted_index.(MEPS) | 51 |
| abstract_inverted_index.0.001) | 150 |
| abstract_inverted_index.HRQoL, | 104 |
| abstract_inverted_index.HRQoL. | 201 |
| abstract_inverted_index.States | 36 |
| abstract_inverted_index.Survey | 50 |
| abstract_inverted_index.United | 35 |
| abstract_inverted_index.adults | 38 |
| abstract_inverted_index.better | 200 |
| abstract_inverted_index.common | 2 |
| abstract_inverted_index.female | 174 |
| abstract_inverted_index.health | 11, 88 |
| abstract_inverted_index.higher | 184, 192 |
| abstract_inverted_index.impact | 229 |
| abstract_inverted_index.invest | 211 |
| abstract_inverted_index.linear | 94 |
| abstract_inverted_index.mental | 27, 79, 152 |
| abstract_inverted_index.public | 178 |
| abstract_inverted_index.reduce | 226 |
| abstract_inverted_index.review | 221 |
| abstract_inverted_index.scores | 82 |
| abstract_inverted_index.years. | 41 |
| abstract_inverted_index.(HRQoL) | 32 |
| abstract_inverted_index.0.001). | 166, 189 |
| abstract_inverted_index.12-item | 85 |
| abstract_inverted_index.Medical | 47 |
| abstract_inverted_index.adults. | 60, 236 |
| abstract_inverted_index.adverse | 10 |
| abstract_inverted_index.applied | 91 |
| abstract_inverted_index.between | 101 |
| abstract_inverted_index.crucial | 209 |
| abstract_inverted_index.factors | 109 |
| abstract_inverted_index.marital | 114 |
| abstract_inverted_index.private | 195 |
| abstract_inverted_index.quality | 29 |
| abstract_inverted_index.routine | 219 |
| abstract_inverted_index.status) | 115 |
| abstract_inverted_index.status, | 177 |
| abstract_inverted_index.summary | 81 |
| abstract_inverted_index.survey. | 89 |
| abstract_inverted_index.analysis | 57 |
| abstract_inverted_index.assessed | 75 |
| abstract_inverted_index.designed | 14 |
| abstract_inverted_index.included | 173 |
| abstract_inverted_index.interval | 141 |
| abstract_inverted_index.negative | 228 |
| abstract_inverted_index.physical | 25, 77, 135 |
| abstract_inverted_index.programs | 213 |
| abstract_inverted_index.reported | 124 |
| abstract_inverted_index.targeted | 215 |
| abstract_inverted_index.−0.22, | 160 |
| abstract_inverted_index.−0.85, | 156 |
| abstract_inverted_index.−1.48, | 159 |
| abstract_inverted_index.−2.26, | 144 |
| abstract_inverted_index.−2.95, | 138 |
| abstract_inverted_index.−3.64, | 143 |
| abstract_inverted_index.(adjusted | 136, 154 |
| abstract_inverted_index.(diabetes | 118 |
| abstract_inverted_index.adjusting | 106 |
| abstract_inverted_index.component | 80 |
| abstract_inverted_index.conducted | 55 |
| abstract_inverted_index.contrast, | 191 |
| abstract_inverted_index.decreased | 134 |
| abstract_inverted_index.determine | 19, 98 |
| abstract_inverted_index.disease). | 121 |
| abstract_inverted_index.education | 193 |
| abstract_inverted_index.findings, | 206 |
| abstract_inverted_index.insurance | 196 |
| abstract_inverted_index.outcomes. | 12 |
| abstract_inverted_index.unmarried | 176 |
| abstract_inverted_index.associated | 8, 132, 198 |
| abstract_inverted_index.confidence | 140 |
| abstract_inverted_index.insurance, | 179 |
| abstract_inverted_index.medication | 220 |
| abstract_inverted_index.nationally | 45 |
| abstract_inverted_index.predictors | 169 |
| abstract_inverted_index.regression | 95 |
| abstract_inverted_index.strategies | 224 |
| abstract_inverted_index.Expenditure | 48 |
| abstract_inverted_index.association | 21 |
| abstract_inverted_index.attainment, | 182 |
| abstract_inverted_index.comorbidity | 185 |
| abstract_inverted_index.educational | 181 |
| abstract_inverted_index.medications | 71 |
| abstract_inverted_index.populations | 5 |
| abstract_inverted_index.significant | 168 |
| abstract_inverted_index.Polypharmacy | 0, 61, 122 |
| abstract_inverted_index.multivariate | 93 |
| abstract_inverted_index.participants | 128 |
| abstract_inverted_index.polypharmacy | 23, 102, 231 |
| abstract_inverted_index.relationship | 100 |
| abstract_inverted_index.comorbidities | 117 |
| abstract_inverted_index.deprescribing | 223 |
| abstract_inverted_index.interventions | 216 |
| abstract_inverted_index.significantly | 131 |
| abstract_inverted_index.cardiovascular | 120 |
| abstract_inverted_index.health-related | 28 |
| abstract_inverted_index.representative | 46 |
| abstract_inverted_index.cross-sectional | 16 |
| abstract_inverted_index.operationalized | 63 |
| abstract_inverted_index.race/ethnicity, | 112 |
| abstract_inverted_index.simultaneously. | 72 |
| abstract_inverted_index.sociodemographic | 108 |
| cited_by_percentile_year | |
| countries_distinct_count | 2 |
| institutions_distinct_count | 4 |
| citation_normalized_percentile.value | 0.78609427 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |