Associations of Culprit Vessel Size and Plaque Characteristics in Patients with ST-Segment Elevation Myocardial Infarction Article Swipe
Jiannan Li
,
Runzhen Chen
,
Jinying Zhou
,
Ying Wang
,
Xiaoxiao Zhao
,
Chen Liu
,
Peng Zhou
,
Yi Chen
,
Song Li
,
Shaodi Yan
,
Hongbing Yan
,
Hanjun Zhao
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.31083/j.rcm2407186
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.31083/j.rcm2407186
Background: Small vessel disease (SVD) widely exists in patients with acute coronary syndrome. However, the plaque characteristic of SVD has not been investigated. Methods: Optical coherence tomography (OCT) of culprit lesion was examined in 576 patients with ST-segment elevation myocardial infarction (STEMI) and finally 404 patients with qualified images were analysed of plaque phenotypes and microstructure. The cohort was divided into three groups according to vessel diameters of culprit lesion which were measured by OCT. Major adverse cardiac events (MACEs) were recorded of each patient and compared among patients with different vessel diameters and plaque phenotypes. Results: Gender, age and body mass index (BMI) were significantly different among patients with different diameters of culprit vessels (98.4% vs. 85.7% vs.71.4%, p < 0.001; 40.0 ± 7.0 vs. 54.9 ± 6.6 vs. 68.9 ± 5.8, p < 0.001; 28.4 ± 4.0 vs. 25.8 ± 2.9 vs. 25.2 ± 3.0, p < 0.001, respectively). Moreover, patients with diameters of culprit lesion >3 mm presented with more incidence of plaque rupture and macrophage (57.7% vs. 42.1% vs. 46.2%, p = 0.015, 55.1% vs. 41.0% vs. 36.9%, p = 0.010). Total MACE did not differ among groups of different vessel diameters and plaque phenotypes. Conclusions: Vessel size of culprit lesion is significantly associated with plaque phenotype in patients with STEMI. However, patients with different diameters and plaque phenotypes showed no significant difference of clinical outcomes. Clinical Trial Registration: NCT03593928.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.31083/j.rcm2407186
- https://www.imrpress.com/journal/RCM/24/7/10.31083/j.rcm2407186/pdf
- OA Status
- gold
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4383553799
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4383553799Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.31083/j.rcm2407186Digital Object Identifier
- Title
-
Associations of Culprit Vessel Size and Plaque Characteristics in Patients with ST-Segment Elevation Myocardial InfarctionWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-06-29Full publication date if available
- Authors
-
Jiannan Li, Runzhen Chen, Jinying Zhou, Ying Wang, Xiaoxiao Zhao, Chen Liu, Peng Zhou, Yi Chen, Song Li, Shaodi Yan, Hongbing Yan, Hanjun ZhaoList of authors in order
- Landing page
-
https://doi.org/10.31083/j.rcm2407186Publisher landing page
- PDF URL
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https://www.imrpress.com/journal/RCM/24/7/10.31083/j.rcm2407186/pdfDirect link to full text PDF
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YesWhether a free full text is available
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-
goldOpen access status per OpenAlex
- OA URL
-
https://www.imrpress.com/journal/RCM/24/7/10.31083/j.rcm2407186/pdfDirect OA link when available
- Concepts
-
Medicine, Culprit, Myocardial infarction, Mace, Cardiology, Internal medicine, Vulnerable plaque, Lesion, Acute coronary syndrome, ST segment, Percutaneous coronary intervention, PathologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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35Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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