AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides Article Swipe

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Amanda M. Acevedo‐Jake , Andrew Ball , Marzia Galli , Mikiembo Kukwikila , Mathieu Denis , Daniel Singleton , Ali Tavassoli , Stephen M. Goldup ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.26434/chemrxiv.11822289

We present a simple strategy for the synthesis of main chain oligonucleotide rotaxanes with precise control over the position of the macrocycle. The novel DNA-based rotaxanes were analyzed to assess the effect of the mechanical bond on their properties.

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Chemistry

Dna

Biochemistry

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Oligonucleotide Chemistry DNA Combinatorial chemistry Stereochemistry Biochemistry

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Type: preprint
Language: en
Landing Page: https://doi.org/10.26434/chemrxiv.11822289
PDF: https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c747f0f96a00ea42286fe2/original/at-cu-aac-synthesis-of-mechanically-interlocked-oligonucleotides.pdf
OA Status: gold
Cited By: 3
References: 99
Related Works: 10
OpenAlex ID: https://openalex.org/W4245693406

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DOI: https://doi.org/10.26434/chemrxiv.11822289

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Title: AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides

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Type: preprint

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Language: en

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Publication year: 2020

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Publication date: 2020-02-07

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Authors: Amanda M. Acevedo‐Jake, Andrew Ball, Marzia Galli, Mikiembo Kukwikila, Mathieu Denis, Daniel Singleton, Ali Tavassoli, Stephen M. Goldup

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Landing page: https://doi.org/10.26434/chemrxiv.11822289

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PDF URL: https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c747f0f96a00ea42286fe2/original/at-cu-aac-synthesis-of-mechanically-interlocked-oligonucleotides.pdf

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Concepts: Oligonucleotide, Chemistry, DNA, Combinatorial chemistry, Stereochemistry, Biochemistry

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Cited by: 3

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Citations by year (recent): 2023: 1, 2020: 2

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References (count): 99

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Related works (count): 10

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