Autoantibodies against granulocyte macrophage colony‐stimulating factor and Nocardia infection in solid organ transplant recipients Article Swipe
David Lebeaux
,
Julien Coussement
,
Cécile Chauvet
,
Marie Matignon
,
Anne Scemla
,
Nicolas Bouvier
,
Jacques Dantal
,
Albert M. Vollaard
,
Herman F. Wunderink
,
Eric Van Wijngaerden
,
Maarten Naesens
,
Nassim Kamar
,
Julien De Greef
,
R. Guillemain
,
Raphaël Borie
,
Sophie Candon
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1111/tri.13727
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1111/tri.13727
Dear Editors, Nocardiosis is a rare but potentially severe bacterial opportunistic infection that may occur after solid organ transplantation (SOT), typically among thoracic transplant recipients and/or in recipients with a high degree of immunosuppression due to anti-rejection therapy [1]. However, nocardiosis may also occur late after transplantation among minimally immunosuppressed patients, suggesting that additional risk factors exist [1]. Recently, autoantibodies against granulocyte macrophage colony-stimulating factor (GM-CSF) have been identified among five previously healthy patients with disseminated nocardiosis [2]. These autoantibodies likely promote nocardiosis by reducing neutrophil and macrophage activation, phagocytosis, and bactericidal activity [2]. We hypothesized that anti-GM-CSF autoantibodies might be involved in post-SOT nocardiosis, especially in patients who apparently have a relatively low degree of immunosuppression. [...]
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Metadata
- Type
- letter
- Language
- en
- Landing Page
- https://doi.org/10.1111/tri.13727
- OA Status
- green
- Cited By
- 3
- References
- 3
- Related Works
- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3082488419Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/tri.13727Digital Object Identifier
- Title
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Autoantibodies against granulocyte macrophage colony‐stimulating factor and Nocardia infection in solid organ transplant recipientsWork title
- Type
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letterOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-09-02Full publication date if available
- Authors
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David Lebeaux, Julien Coussement, Cécile Chauvet, Marie Matignon, Anne Scemla, Nicolas Bouvier, Jacques Dantal, Albert M. Vollaard, Herman F. Wunderink, Eric Van Wijngaerden, Maarten Naesens, Nassim Kamar, Julien De Greef, R. Guillemain, Raphaël Borie, Sophie CandonList of authors in order
- Landing page
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https://doi.org/10.1111/tri.13727Publisher landing page
- Open access
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://hdl.handle.net/2078.1/251889Direct OA link when available
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Medicine, Transplantation, Library science, Internal medicine, Computer scienceTop concepts (fields/topics) attached by OpenAlex
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3Total citation count in OpenAlex
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2025: 1, 2024: 2Per-year citation counts (last 5 years)
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3Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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