AutoLEI: An XDS-based Graphical User Interface for Automated Real-time and Offline Batch 3D ED/MicroED Data Processing Article Swipe
Lei Wang
,
Yinlin Chen
,
Emma Rose Scaletti
,
Pål Stenmark
,
Gerhard Höfer
,
Hongyi Xu
,
Xiaodong Zou
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1101/2025.04.12.648515
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1101/2025.04.12.648515
Three-dimensional electron diffraction (3D ED), also known as microcrystal electron diffraction (MicroED), is an emerging method for determining structures of submicron-sized crystals. With the development of rapid and convenient data collection protocols, acquiring dozens of datasets in a single MicroED session has become routine. A fast and automated workflow for processing, scaling and merging a large number of MicroED datasets can significantly accelerate the structure determination process. Herein, we present an XDS-based graphical user interface for auto mated rea l -tim e and offl i ne batch 3D ED/MicroED data processing (AutoLEI). We illustrate the functionality of the GUI through four examples, demonstrating both offline and real-time data processing capabilities. These examples include small organic molecules, metal-organic frameworks (MOFs), and proteins, showcasing the versatility and efficiency of the GUI in various applications. Synopsis A graphical user interface for real-time and offline 3D ED/MicroED data processing by XDS was developed. The GUI aims to improve efficiency, minimize redundant data processing work, and provide users with real-time feedback during data collection.
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2025.04.12.648515
- https://www.biorxiv.org/content/biorxiv/early/2025/04/12/2025.04.12.648515.full.pdf
- OA Status
- green
- References
- 37
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4409393909
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4409393909Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/2025.04.12.648515Digital Object Identifier
- Title
-
AutoLEI: An XDS-based Graphical User Interface for Automated Real-time and Offline Batch 3D ED/MicroED Data ProcessingWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-04-12Full publication date if available
- Authors
-
Lei Wang, Yinlin Chen, Emma Rose Scaletti, Pål Stenmark, Gerhard Höfer, Hongyi Xu, Xiaodong ZouList of authors in order
- Landing page
-
https://doi.org/10.1101/2025.04.12.648515Publisher landing page
- PDF URL
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https://www.biorxiv.org/content/biorxiv/early/2025/04/12/2025.04.12.648515.full.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
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https://www.biorxiv.org/content/biorxiv/early/2025/04/12/2025.04.12.648515.full.pdfDirect OA link when available
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Graphical user interface, Computer science, Interface (matter), Online and offline, Human–computer interaction, Operating system, Bubble, Maximum bubble pressure methodTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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37Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.submicron-sized | 21 |
| abstract_inverted_index.Three-dimensional | 1 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 7 |
| citation_normalized_percentile.value | 0.12481154 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |