Avaliação da eficácia do ácido tranexâmico em drug delivery através de microagulhamento no tratamento do melasma Article Swipe

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Dâmia Kuster Kaminski Arida , Thelma Larocca Skare , Luciana Rodrigues Lisboa Faucz , Ronaldo Máfia Cuenca , Nicolau Gregori Czeczko , Paulo Afonso Nunes Nassif ·

YOU? · · 2024 · Open Access · · DOI: https://doi.org/10.55684/2024.82.e034

Introdução: O melasma é um distúrbio de pigmentação da pele prevalente e de difícil tratamento. O ácido tranexâmico é agente potencial, mas há poucos estudos sobre sua eficácia pela via transdérmica (drug delivery). Objetivo: Revisar a eficácia e perfil de segurança do ácido tranexâmico quando aplicado na forma de drug delivery através de microagulhamento no tratamento do melasma facial. Métodos: Esta revisão colheu dados publicados em plataformas virtuais em português e inglês por busca através de descritores MESH/DeCS, com os termos: “melasma, ácido tranexâmico, drug delivery, microagulhamento” e em inglês “melasma, tranexamic acid, drug delivery, microneedling” com busca AND ou OR, pelo título ou resumo. Em seguida, considerando-se os de maior relação ao tema, foi lida a íntegra dos textos. Resultado: Foram incluídos 24 artigos. Conclusão: O ácido tranexâmico em drug delivery por meio de microagulhamento não se mostrou eficaz. No entanto, apresentou segurança clínica e tolerabilidade.

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Melasma Medicine Drug Dermatology Pharmacology

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Language: pt
Landing Page: https://doi.org/10.55684/2024.82.e034
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DOI: https://doi.org/10.55684/2024.82.e034

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Title: Avaliação da eficácia do ácido tranexâmico em drug delivery através de microagulhamento no tratamento do melasma

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Type: article

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Language: pt

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Publication year: 2024

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Publication date: 2024-06-17

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Authors: Dâmia Kuster Kaminski Arida, Thelma Larocca Skare, Luciana Rodrigues Lisboa Faucz, Ronaldo Máfia Cuenca, Nicolau Gregori Czeczko, Paulo Afonso Nunes Nassif

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Landing page: https://doi.org/10.55684/2024.82.e034

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Open access: Yes

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OA status: hybrid

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OA URL: https://doi.org/10.55684/2024.82.e034

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Concepts: Melasma, Medicine, Drug, Dermatology, Pharmacology

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Related works (count): 10

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