Barrier dysfunction in nasal epithelium contributes to persistent inflammation in long COVID Article Swipe
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Nadia Baalbaki
,
Daniëlle van Egmond
,
Patricia Jaeger
,
Merel E.B. Cornelissen
,
Sien T. Verbeek
,
Milena Sokołowska
,
Cornelis M. van Drunen
,
Anke H. Maitland‐van der Zee
,
Korneliusz Golebski
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.jaci.2025.09.024
· OA: W4414938587
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1016/j.jaci.2025.09.024
· OA: W4414938587
While multiple organ systems are implicated in LC, our findings identified nasal epithelial dysfunction in a subgroup of LC patients and chronic activation as potential contributors to systemic immune dysregulation. The IL-1β-IFN-γ axis represents a novel targetable pathway that may support precision therapies for LC.
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