Behavioral and Neural Signatures of Working Memory in Childhood Article Swipe
YOU?
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· 2020
· Open Access
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· DOI: https://doi.org/10.1523/jneurosci.2841-19.2020
Working memory function changes across development and varies across individuals. The patterns of behavior and brain function that track individual differences in working memory during human development, however, are not well understood. Here, we establish associations between working memory, other cognitive abilities, and functional MRI (fMRI) activation in data from over 11,500 9- to 10-year-old children (both sexes) enrolled in the Adolescent Brain Cognitive Development (ABCD) Study, an ongoing longitudinal study in the United States. Behavioral analyses reveal robust relationships between working memory, short-term memory, language skills, and fluid intelligence. Analyses relating out-of-scanner working memory performance to memory-related fMRI activation in an emotional n-back task demonstrate that frontoparietal activity during a working memory challenge indexes working memory performance. This relationship is domain specific, such that fMRI activation related to emotion processing during the emotional n-back task, inhibitory control during a stop-signal task (SST), and reward processing during a monetary incentive delay (MID) task does not track memory abilities. Together, these results inform our understanding of individual differences in working memory in childhood and lay the groundwork for characterizing the ways in which they change across adolescence. SIGNIFICANCE STATEMENT Working memory is a foundational cognitive ability that changes over time and varies across individuals. Here, we analyze data from over 11,500 9- to 10-year-olds to establish relationships between working memory, other cognitive abilities, and frontoparietal brain activity during a working memory challenge, but not during other cognitive challenges. Our results lay the groundwork for assessing longitudinal changes in working memory and predicting later academic and other real-world outcomes.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1523/jneurosci.2841-19.2020
- https://www.jneurosci.org/content/jneuro/40/26/5090.full.pdf
- OA Status
- bronze
- Cited By
- 94
- References
- 117
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3028337256
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3028337256Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1523/jneurosci.2841-19.2020Digital Object Identifier
- Title
-
Behavioral and Neural Signatures of Working Memory in ChildhoodWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-05-25Full publication date if available
- Authors
-
Monica D. Rosenberg, Steven A. Martinez, Kristina M. Rapuano, May I. Conley, Alexandra O. Cohen, M. Daniela Cornejo, Donald J. Hagler, W.J. MEREDITH, Kevin Anderson, Tor D. Wager, Eric Feczko, Eric Earl, Damien A. Fair, Deanna M. Barch, Richard Watts, B. J. CaseyList of authors in order
- Landing page
-
https://doi.org/10.1523/jneurosci.2841-19.2020Publisher landing page
- PDF URL
-
https://www.jneurosci.org/content/jneuro/40/26/5090.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
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https://www.jneurosci.org/content/jneuro/40/26/5090.full.pdfDirect OA link when available
- Concepts
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Working memory, Psychology, Cognitive psychology, Cognition, Childhood memory, Functional magnetic resonance imaging, Short-term memory, Episodic memory, NeuroscienceTop concepts (fields/topics) attached by OpenAlex
- Cited by
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94Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 17, 2024: 21, 2023: 16, 2022: 15, 2021: 19Per-year citation counts (last 5 years)
- References (count)
-
117Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.which | 181 |
| abstract_inverted_index.(ABCD) | 65 |
| abstract_inverted_index.(SST), | 142 |
| abstract_inverted_index.(fMRI) | 45 |
| abstract_inverted_index.11,500 | 51, 209 |
| abstract_inverted_index.Study, | 66 |
| abstract_inverted_index.United | 73 |
| abstract_inverted_index.across | 4, 8, 184, 201 |
| abstract_inverted_index.change | 183 |
| abstract_inverted_index.domain | 121 |
| abstract_inverted_index.during | 24, 109, 131, 138, 146, 226, 233 |
| abstract_inverted_index.inform | 161 |
| abstract_inverted_index.memory | 1, 23, 94, 112, 116, 156, 169, 189, 229, 248 |
| abstract_inverted_index.n-back | 103, 134 |
| abstract_inverted_index.reveal | 77 |
| abstract_inverted_index.reward | 144 |
| abstract_inverted_index.robust | 78 |
| abstract_inverted_index.sexes) | 57 |
| abstract_inverted_index.varies | 7, 200 |
| abstract_inverted_index.States. | 74 |
| abstract_inverted_index.Working | 0, 188 |
| abstract_inverted_index.ability | 194 |
| abstract_inverted_index.analyze | 205 |
| abstract_inverted_index.between | 36, 80, 216 |
| abstract_inverted_index.changes | 3, 196, 245 |
| abstract_inverted_index.control | 137 |
| abstract_inverted_index.emotion | 129 |
| abstract_inverted_index.indexes | 114 |
| abstract_inverted_index.memory, | 38, 82, 84, 218 |
| abstract_inverted_index.ongoing | 68 |
| abstract_inverted_index.related | 127 |
| abstract_inverted_index.results | 160, 238 |
| abstract_inverted_index.skills, | 86 |
| abstract_inverted_index.working | 22, 37, 81, 93, 111, 115, 168, 217, 228, 247 |
| abstract_inverted_index.Analyses | 90 |
| abstract_inverted_index.academic | 252 |
| abstract_inverted_index.activity | 108, 225 |
| abstract_inverted_index.analyses | 76 |
| abstract_inverted_index.behavior | 13 |
| abstract_inverted_index.children | 55 |
| abstract_inverted_index.enrolled | 58 |
| abstract_inverted_index.function | 2, 16 |
| abstract_inverted_index.however, | 27 |
| abstract_inverted_index.language | 85 |
| abstract_inverted_index.monetary | 148 |
| abstract_inverted_index.patterns | 11 |
| abstract_inverted_index.relating | 91 |
| abstract_inverted_index.Cognitive | 63 |
| abstract_inverted_index.STATEMENT | 187 |
| abstract_inverted_index.Together, | 158 |
| abstract_inverted_index.assessing | 243 |
| abstract_inverted_index.challenge | 113 |
| abstract_inverted_index.childhood | 171 |
| abstract_inverted_index.cognitive | 40, 193, 220, 235 |
| abstract_inverted_index.emotional | 102, 133 |
| abstract_inverted_index.establish | 34, 214 |
| abstract_inverted_index.incentive | 149 |
| abstract_inverted_index.outcomes. | 256 |
| abstract_inverted_index.specific, | 122 |
| abstract_inverted_index.Adolescent | 61 |
| abstract_inverted_index.Behavioral | 75 |
| abstract_inverted_index.abilities, | 41, 221 |
| abstract_inverted_index.abilities. | 157 |
| abstract_inverted_index.activation | 46, 99, 126 |
| abstract_inverted_index.challenge, | 230 |
| abstract_inverted_index.functional | 43 |
| abstract_inverted_index.groundwork | 175, 241 |
| abstract_inverted_index.individual | 19, 165 |
| abstract_inverted_index.inhibitory | 136 |
| abstract_inverted_index.predicting | 250 |
| abstract_inverted_index.processing | 130, 145 |
| abstract_inverted_index.real-world | 255 |
| abstract_inverted_index.short-term | 83 |
| abstract_inverted_index.10-year-old | 54 |
| abstract_inverted_index.Development | 64 |
| abstract_inverted_index.challenges. | 236 |
| abstract_inverted_index.demonstrate | 105 |
| abstract_inverted_index.development | 5 |
| abstract_inverted_index.differences | 20, 166 |
| abstract_inverted_index.performance | 95 |
| abstract_inverted_index.stop-signal | 140 |
| abstract_inverted_index.understood. | 31 |
| abstract_inverted_index.10-year-olds | 212 |
| abstract_inverted_index.SIGNIFICANCE | 186 |
| abstract_inverted_index.adolescence. | 185 |
| abstract_inverted_index.associations | 35 |
| abstract_inverted_index.development, | 26 |
| abstract_inverted_index.foundational | 192 |
| abstract_inverted_index.individuals. | 9, 202 |
| abstract_inverted_index.longitudinal | 69, 244 |
| abstract_inverted_index.performance. | 117 |
| abstract_inverted_index.relationship | 119 |
| abstract_inverted_index.intelligence. | 89 |
| abstract_inverted_index.relationships | 79, 215 |
| abstract_inverted_index.understanding | 163 |
| abstract_inverted_index.characterizing | 177 |
| abstract_inverted_index.frontoparietal | 107, 223 |
| abstract_inverted_index.memory-related | 97 |
| abstract_inverted_index.out-of-scanner | 92 |
| cited_by_percentile_year.max | 100 |
| cited_by_percentile_year.min | 98 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 16 |
| citation_normalized_percentile.value | 0.97570063 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |