Bibliometric analysis of research trends in stem cell therapy for knee osteoarthritis over the period 2001–2021 Article Swipe
Runzhi Chen
,
Yanyan Jiang
,
Laiya Lu
,
Pei Wang
,
Dongya Huang
,
Jingyi Wang
,
Zheng Liu
,
Shaojie Qin
,
Feng Yin
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3389/fcell.2022.996273
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3389/fcell.2022.996273
Stem cell therapy is a promising treatment for knee osteoarthritis, but few bibliometric studies have been performed on the subject. Bibliometric analysis is helpful for identifying the most influential studies in a specific field and can evaluate the global research trends in stem cell therapy for knee osteoarthritis. The Web of Science Core Collection was searched for publications from 2001 to 2021. Publication performance was analyzed using several bibliometric parameters, including VOSviewer, to identify the research landscape of trends in topics, and CiteSpace was investigated to identify the keywords that have the strongest citation bursts. From 2001 to 2021, in total, 1,345 publications explored the research on stem cells in knee osteoarthritis. The United States contributed the largest number of publications and at the top list of international collaborations. Tokyo Medical and Dental University ranked first among institutions in the overall number of articles and citations. The journal of Osteoarthritis and Cartilage had the largest number of publications. Sekiya Ichiro was the most cited author, with 32 articles. The keywords with the most frequent occurrence were “osteoarthritis,” “mesenchymal stem cells,” and “cartilage,” in descending order of frequency. “fibroblast growth factor” and “extracellular vesicle” were the first and last searched theme terms, respectively. The number of publications on stem cells for knee osteoarthritis stays growing. Cartilage repair and paracrine function are current research hotspots for the stem cell therapy mechanism. Stem cell therapy has gradually advanced from basic research to the clinical application stage.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fcell.2022.996273
- https://www.frontiersin.org/articles/10.3389/fcell.2022.996273/pdf
- OA Status
- gold
- Cited By
- 14
- References
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- Related Works
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- OpenAlex ID
- https://openalex.org/W4306759164
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4306759164Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fcell.2022.996273Digital Object Identifier
- Title
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Bibliometric analysis of research trends in stem cell therapy for knee osteoarthritis over the period 2001–2021Work title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-10-18Full publication date if available
- Authors
-
Runzhi Chen, Yanyan Jiang, Laiya Lu, Pei Wang, Dongya Huang, Jingyi Wang, Zheng Liu, Shaojie Qin, Feng YinList of authors in order
- Landing page
-
https://doi.org/10.3389/fcell.2022.996273Publisher landing page
- PDF URL
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https://www.frontiersin.org/articles/10.3389/fcell.2022.996273/pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
- OA URL
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https://www.frontiersin.org/articles/10.3389/fcell.2022.996273/pdfDirect OA link when available
- Concepts
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Osteoarthritis, Medicine, Stem cell, Cartilage, Pathology, Biology, Alternative medicine, Anatomy, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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14Total citation count in OpenAlex
- Citations by year (recent)
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2025: 5, 2024: 6, 2023: 3Per-year citation counts (last 5 years)
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27Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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