Biodynamic lighting conditions preserve nocturnal melatonin production in pregnant women during hospitalization: A randomized prospective pilot study Article Swipe
Soyhan Bağcı
,
Astrid Wieduwilt
,
Ebru Aileen Alsat
,
Jana Blickwedel
,
Brigitte Strizek
,
Christian Di Battista
,
Agnes Lachner
,
Herbert Plischke
,
Tamene Melaku
,
Andreas Müller
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3389/fendo.2022.1043366
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3389/fendo.2022.1043366
Background and purpose Maternal circadian rhythms are important for maintaining maternal and fetal homeostasis. The maternal circadian system coordinates the internal clock of the fetus with environmental lighting conditions via the melatonin signal. The intensity and wavelength of daylight influence nocturnal melatonin production. This study aims to evaluate the effect of environmental lighting conditions on melatonin production in pregnant women with reduced mobility during hospitalization. Methods We installed a human-centric lighting system with biodynamic effects (BDL, biodynamic lighting) in the patient rooms. The pregnant women in the patient rooms with standard indoor conditions served as a control group. The illuminance (lux) and dose of effective circadian irradiation (Hec) were recorded every 10 seconds by light dosimeters (Lucerne University, Switzerland) attached to the patients` clothing. Results We analyzed the illuminance status of 47 pregnant women with a median (IQR) gestational age of 29.9 (25.4-32.3) weeks of gestation. The median illuminance in the control group was significantly lower (p<0.05) than in the BDL group in the morning and afternoon from day 1 to 5. BDL patients had a significantly higher effective circadian irradiation in the morning. The effective circadian irradiation showed a significant daily rhythm only in the BDL group. The BDL group had a significantly higher melatonin production on day 3 (p=0.006) and day 5 (p=0.012) than the control group median (IQR) nocturnal 6-Sulfatoxymelatonin excretion 15840 (10140-22160) ng/12h vs. 6141 (2080-11328) ng/12h on day 3 and 18780 (11320-23562) ng/12h vs. 6380 (3500-17600) ng/12h on day 5). Conclusion We have demonstrated that dramatically altered lighting conditions of hospitalized pregnant women may be optimized by installing biodynamic lighting systems in the patient rooms resulting in the maintenance of nocturnal melatonin production in pregnant women.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fendo.2022.1043366
- OA Status
- gold
- Cited By
- 1
- References
- 35
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4311875545
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4311875545Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fendo.2022.1043366Digital Object Identifier
- Title
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Biodynamic lighting conditions preserve nocturnal melatonin production in pregnant women during hospitalization: A randomized prospective pilot studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-12-08Full publication date if available
- Authors
-
Soyhan Bağcı, Astrid Wieduwilt, Ebru Aileen Alsat, Jana Blickwedel, Brigitte Strizek, Christian Di Battista, Agnes Lachner, Herbert Plischke, Tamene Melaku, Andreas MüllerList of authors in order
- Landing page
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https://doi.org/10.3389/fendo.2022.1043366Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.3389/fendo.2022.1043366Direct OA link when available
- Concepts
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Melatonin, Circadian rhythm, Medicine, Morning, Nocturnal, Pregnancy, Internal medicine, Endocrinology, Physiology, Biology, GeneticsTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2024: 1Per-year citation counts (last 5 years)
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35Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| institutions_distinct_count | 10 |
| corresponding_institution_ids | https://openalex.org/I135140700, https://openalex.org/I2799391451 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.6700000166893005 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.43823264 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |