Biomarkers of Myocardial Injury and Remodeling in Heart Failure Article Swipe
Barbara Ponikowska
,
Gracjan Iwanek
,
Agata Zdanowicz
,
Szymon Urban
,
Robert Zymliński
,
Piotr Ponikowski
,
Jan Biegus
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/jpm12050799
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/jpm12050799
With its complicated pathophysiology, high incidence and prevalence, heart failure remains a major public concern. In hopes of improving diagnosis, treatment and prognosis, the utility of many different biomarkers is researched vigorously around the world. In this review, biomarkers of myocardial remodeling and fibrosis (galectin-3, soluble isoform of suppression of tumorigenicity 2, matrix metalloproteinases, osteopontin, interleukin-6, syndecan-4, myostatin, procollagen type I C-terminal propeptide, procollagen type III N-terminal propeptide, vascular endothelial growth factor, nitric oxidase synthetase and asymmetric dimethylarginine), myocyte injury (heart-type fatty acid-binding protein, glutathione S-transferase P1 and heat shock protein 60), as well as iron metabolism (ferritin, transferrin saturation, soluble transferrin receptor and hepcidin), are considered in terms of possible clinical applicability and significance. Our short review consists of a summary of the aforementioned cardiovascular biomarkers’ clinical relevance and perspectives.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3390/jpm12050799
- https://www.mdpi.com/2075-4426/12/5/799/pdf?version=1652674760
- OA Status
- gold
- Cited By
- 32
- References
- 74
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4280569324
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4280569324Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/jpm12050799Digital Object Identifier
- Title
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Biomarkers of Myocardial Injury and Remodeling in Heart FailureWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-05-16Full publication date if available
- Authors
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Barbara Ponikowska, Gracjan Iwanek, Agata Zdanowicz, Szymon Urban, Robert Zymliński, Piotr Ponikowski, Jan BiegusList of authors in order
- Landing page
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https://doi.org/10.3390/jpm12050799Publisher landing page
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https://www.mdpi.com/2075-4426/12/5/799/pdf?version=1652674760Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2075-4426/12/5/799/pdf?version=1652674760Direct OA link when available
- Concepts
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Heart failure, Medicine, Procollagen peptidase, GDF15, Myocardial fibrosis, Internal medicine, Fibrosis, Osteopontin, Protein precursor, Endocrinology, Biology, Biochemistry, GeneTop concepts (fields/topics) attached by OpenAlex
- Cited by
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32Total citation count in OpenAlex
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2025: 7, 2024: 11, 2023: 10, 2022: 4Per-year citation counts (last 5 years)
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74Number of works referenced by this work
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-
10Other works algorithmically related by OpenAlex
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