Bone Tumors: Types and Treatments Article Swipe
Geetanjali B. Tomar
,
Jay R. Dave
,
Sayali S. Chandekar
,
Suhas T. Mhaske
·
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.5772/intechopen.86550
YOU?
·
· 2019
· Open Access
·
· DOI: https://doi.org/10.5772/intechopen.86550
The tumors associated with bone are mostly of mesenchymal origin and contribute to approximately 1% of all the known tumors. These could be primary/benign tumors (that originate in the bone), secondary tumors (that originate in some other tissue/organ and metastasize to the bone), or malignant primary bone tumors (that originate in bone and metastasize to distant tissue). These tumors are majorly due to defects in the regulation of tumor suppressor genes and oncogenes and/or misregulation of signal transduction pathways. Chemotherapy and radiotherapy used for the treatment have several side effects. During the recent years, therapeutic strategies involving hormone deprivation (estrogen, androgen), hormone replacements (estrogen analogs), hormone receptor modulators (SERMs), growth factors and cytokines, small-molecule inhibitors, and gene therapy have emerged as a promising alternative to chemo- and radiotherapy. In the present chapter, we have provided an extensive account of tumors associated with the bone and various therapeutic options related to hormone deprivation, hormone replacements, hormone receptor modulators, and hormone inhibition.
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Bone Tumors: Types and TreatmentsWork title
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book-chapterOpenAlex work type
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enPrimary language
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2019Year of publication
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2019-06-03Full publication date if available
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Geetanjali B. Tomar, Jay R. Dave, Sayali S. Chandekar, Suhas T. MhaskeList of authors in order
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https://doi.org/10.5772/intechopen.86550Publisher landing page
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YesWhether a free full text is available
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hybridOpen access status per OpenAlex
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https://doi.org/10.5772/intechopen.86550Direct OA link when available
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Cancer research, Radiation therapy, Hormone, Medicine, Estrogen, Biology, Internal medicine, EndocrinologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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