Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics Article Swipe

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Sami Ullah , Ronny Beer , Uwe Fuhr , Max Taubert , Markus Zeitlinger , Alexander Kratzer , Christoph Dorn , Usman Arshad , Mario Kofler , Raimund Helbok ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.1007/s12028-020-00947-x

Limited CNS exposure of piperacillin might be an obstacle in treating patients without general meningeal inflammation except for infections with highly susceptible pathogens. Brain exposure of piperacillin did not improve significantly with a prolongation of infusions.

Related Topics

Medicine

Piperacillin/Tazobactam

Subarachnoid Hemorrhage

Anesthesia

Pharmacology

Internal Medicine

Central Nervous System

Pseudomonas Aeruginosa

Engineering

Mechanical Engineering

Bacteria

Biology

Environmental Health

Concepts

Medicine Piperacillin Microdialysis Pharmacokinetics Piperacillin/tazobactam Subarachnoid hemorrhage Intracerebral hemorrhage Anesthesia Stroke (engine) Tazobactam Dosing Pharmacodynamics Neurointensive care Population Pharmacology Internal medicine Central nervous system Pseudomonas aeruginosa Engineering Genetics Mechanical engineering Bacteria Biology Environmental health

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Type: article
Language: en
Landing Page: https://doi.org/10.1007/s12028-020-00947-x
PDF: https://link.springer.com/content/pdf/10.1007/s12028-020-00947-x.pdf
OA Status: hybrid
Cited By: 13
References: 42
Related Works: 10
OpenAlex ID: https://openalex.org/W3013922054

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OpenAlex ID: https://openalex.org/W3013922054

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DOI: https://doi.org/10.1007/s12028-020-00947-x

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Title: Brain Exposure to Piperacillin in Acute Hemorrhagic Stroke Patients Assessed by Cerebral Microdialysis and Population Pharmacokinetics

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Type: article

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Language: en

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Publication year: 2020

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Publication date: 2020-03-26

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Authors: Sami Ullah, Ronny Beer, Uwe Fuhr, Max Taubert, Markus Zeitlinger, Alexander Kratzer, Christoph Dorn, Usman Arshad, Mario Kofler, Raimund Helbok

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Landing page: https://doi.org/10.1007/s12028-020-00947-x

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PDF URL: https://link.springer.com/content/pdf/10.1007/s12028-020-00947-x.pdf

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OA status: hybrid

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OA URL: https://link.springer.com/content/pdf/10.1007/s12028-020-00947-x.pdf

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Concepts: Medicine, Piperacillin, Microdialysis, Pharmacokinetics, Piperacillin/tazobactam, Subarachnoid hemorrhage, Intracerebral hemorrhage, Anesthesia, Stroke (engine), Tazobactam, Dosing, Pharmacodynamics, Neurointensive care, Population, Pharmacology, Internal medicine, Central nervous system, Pseudomonas aeruginosa, Engineering, Genetics, Mechanical engineering, Bacteria, Biology, Environmental health

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Cited by: 13

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Citations by year (recent): 2025: 1, 2024: 2, 2023: 3, 2022: 4, 2021: 3

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References (count): 42

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Related works (count): 10

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