Bridging Biology and Therapy: Advances in Management of Bipolar Disorder Article Swipe
Velmurugan, Varsha
,
Nath, Deborshi
,
Chandy, Vineeth
,
Perumal, Visaga
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.17548760
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.17548760
Bipolar disorder is a complex psychiatric illness that is characterized by alternating episodes of mania and depression that significantly affect the quality of life. It is a chronic condition that has multifactorial pathophysiological mechanisms that remain incompletely understood, and therapeutic outcomes often fail to achieve long-term remission. This review visits the changing landscape of the development of bipolar disorder, in particular, the contributions of metabolic dysfunction and diabetes, which are increasingly acknowledged as important contributors to disease onset, progression, and treatment resistance. The review also explores current advancements, both pharmacological and non-pharmacological advancements for the management of the disease. By integrating the insights from several biological domains, the need for a broader and personalized treatment paradigm that goes beyond neurotransmitter theories is highlighted for improving patient outcomes.
Related Topics
Concepts
Bipolar disorder
Mania
Neurotransmitter systems
Bipolar illness
Disease
Neuroscience
Treatment of bipolar disorder
Psychology
Psychiatry
Medicine
Psychotherapist
Bridging (networking)
Quality of life (healthcare)
Depression (economics)
Endophenotype
Clinical Practice
Mental illness
Neuropharmacology
MEDLINE
Schizophrenia (object-oriented programming)
Complex disease
Clinical psychiatry
Management of depression
Intensive care medicine
Major depressive disorder
Bioinformatics
Disease management
Chronic disease
Affect (linguistics)
Human immunodeficiency virus (HIV)
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.5281/zenodo.17548760
- OA Status
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- OpenAlex ID
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https://openalex.org/W7104424401Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5281/zenodo.17548760Digital Object Identifier
- Title
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Bridging Biology and Therapy: Advances in Management of Bipolar DisorderWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-10-31Full publication date if available
- Authors
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Velmurugan, Varsha, Nath, Deborshi, Chandy, Vineeth, Perumal, VisagaList of authors in order
- Landing page
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https://doi.org/10.5281/zenodo.17548760Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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greenOpen access status per OpenAlex
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https://doi.org/10.5281/zenodo.17548760Direct OA link when available
- Concepts
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Bipolar disorder, Mania, Neurotransmitter systems, Bipolar illness, Disease, Neuroscience, Treatment of bipolar disorder, Psychology, Psychiatry, Medicine, Psychotherapist, Bridging (networking), Quality of life (healthcare), Depression (economics), Endophenotype, Clinical Practice, Mental illness, Neuropharmacology, MEDLINE, Schizophrenia (object-oriented programming), Complex disease, Clinical psychiatry, Management of depression, Intensive care medicine, Major depressive disorder, Bioinformatics, Disease management, Chronic disease, Affect (linguistics), Human immunodeficiency virus (HIV)Top concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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