Burkholderia cepacia complex as a cause of community acquired bacteremia in a young immuncompetent male Article Swipe

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Ceftazidime Bacteremia Burkholderia cepacia complex Medicine Burkholderia Pericarditis Microbiology Internal medicine Antibiotics Biology Pseudomonas aeruginosa Bacteria Genetics

Tanu Singhal , Sunil P. Wani , Sweta Shah , Pooja Thakkar , Vidisha Daiya , Balaji Veeraraghavan ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1016/j.ijmmb.2023.100422 · OA: W4384575474

Burkholderia cepacia complex (BCC) is a well-recognized cause of nosocomial infections. We describe here a young healthy male who presented with fever and chest pain with ECG changes of acute pericarditis. Two sets of blood cultures at separate timings grew gram negative bacilli identified as BCC by molecular methods. The patient responded to intravenous ceftazidime despite high ceftazidime MIC's. The source of infection was probably contaminated nasal spray/nasal saline wash which he used after a balloon sinoplasty procedure one month ago. Issues related to accurate identification and susceptibility testing of BCC are also discussed.