Calpain-Mediated Positional Information Directs Cell Wall Orientation to Sustain Plant Stem Cell Activity, Growth and Development Article Swipe
Zhe Liang
,
Roy C. Brown
,
Jennifer C. Fletcher
,
Hilde-Gunn Opsahl-Sorteberg
·
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1093/pcp/pcv110
YOU?
·
· 2015
· Open Access
·
· DOI: https://doi.org/10.1093/pcp/pcv110
Eukaryotic development and stem cell control depend on the integration of cell positional sensing with cell cycle control and cell wall positioning, yet few factors that directly link these events are known. The DEFECTIVE KERNEL1 (DEK1) gene encoding the unique plant calpain protein is fundamental for development and growth, being essential to confer and maintain epidermal cell identity that allows development beyond the globular embryo stage. We show that DEK1 expression is highest in the actively dividing cells of seeds, meristems and vasculature. We further show that eliminating Arabidopsis DEK1 function leads to changes in developmental cues from the first zygotic division onward, altered microtubule patterns and misshapen cells, resulting in early embryo abortion. Expression of the embryonic marker genes WOX2, ATML1, PIN4, WUS and STM, related to axis organization, cell identity and meristem functions, is also altered in dek1 embryos. By monitoring cell layer-specific DEK1 down-regulation, we show that L1- and 35S-induced down-regulation mainly affects stem cell functions, causing severe shoot apical meristem phenotypes. These results are consistent with a requirement for DEK1 to direct layer-specific cellular activities and set downstream developmental cues. Our data suggest that DEK1 may anchor cell wall positions and control cell division and differentiation, thereby balancing the plant's requirement to maintain totipotent stem cell reservoirs while simultaneously directing growth and organ formation. A role for DEK1 in regulating microtubule-orchestrated cell wall orientation during cell division can explain its effects on embryonic development, and suggests a more general function for calpains in microtubule organization in eukaryotic cells.
Related Topics
Concepts
Cell biology
Meristem
Biology
Totipotent
Cell division
Embryonic stem cell
Cell growth
Stem cell
Arabidopsis
Cellular differentiation
Cell
Cell fate determination
Genetics
Gene
Transcription factor
Mutant
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/pcp/pcv110
- https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdf
- OA Status
- bronze
- Cited By
- 30
- References
- 70
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2165811783
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2165811783Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1093/pcp/pcv110Digital Object Identifier
- Title
-
Calpain-Mediated Positional Information Directs Cell Wall Orientation to Sustain Plant Stem Cell Activity, Growth and DevelopmentWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2015Year of publication
- Publication date
-
2015-07-27Full publication date if available
- Authors
-
Zhe Liang, Roy C. Brown, Jennifer C. Fletcher, Hilde-Gunn Opsahl-SortebergList of authors in order
- Landing page
-
https://doi.org/10.1093/pcp/pcv110Publisher landing page
- PDF URL
-
https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdfDirect OA link when available
- Concepts
-
Cell biology, Meristem, Biology, Totipotent, Cell division, Embryonic stem cell, Cell growth, Stem cell, Arabidopsis, Cellular differentiation, Cell, Cell fate determination, Genetics, Gene, Transcription factor, MutantTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
30Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 8, 2023: 3, 2022: 2, 2021: 5, 2020: 2Per-year citation counts (last 5 years)
- References (count)
-
70Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2165811783 |
|---|---|
| doi | https://doi.org/10.1093/pcp/pcv110 |
| ids.doi | https://doi.org/10.1093/pcp/pcv110 |
| ids.mag | 2165811783 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/26220906 |
| ids.openalex | https://openalex.org/W2165811783 |
| fwci | 2.71159597 |
| mesh[0].qualifier_ui | Q000166 |
| mesh[0].descriptor_ui | D017360 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | cytology |
| mesh[0].descriptor_name | Arabidopsis |
| mesh[1].qualifier_ui | Q000196 |
| mesh[1].descriptor_ui | D017360 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | embryology |
| mesh[1].descriptor_name | Arabidopsis |
| mesh[2].qualifier_ui | Q000201 |
| mesh[2].descriptor_ui | D017360 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | enzymology |
| mesh[2].descriptor_name | Arabidopsis |
| mesh[3].qualifier_ui | Q000378 |
| mesh[3].descriptor_ui | D029681 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | metabolism |
| mesh[3].descriptor_name | Arabidopsis Proteins |
| mesh[4].qualifier_ui | Q000378 |
| mesh[4].descriptor_ui | D002154 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | metabolism |
| mesh[4].descriptor_name | Calpain |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D002455 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Cell Division |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D049109 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Cell Proliferation |
| mesh[7].qualifier_ui | Q000378 |
| mesh[7].descriptor_ui | D002473 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | metabolism |
| mesh[7].descriptor_name | Cell Wall |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D018507 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Gene Expression Regulation, Developmental |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D018506 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Gene Expression Regulation, Plant |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D018519 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Meristem |
| mesh[11].qualifier_ui | Q000378 |
| mesh[11].descriptor_ui | D008870 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | metabolism |
| mesh[11].descriptor_name | Microtubules |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D010641 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Phenotype |
| mesh[13].qualifier_ui | Q000378 |
| mesh[13].descriptor_ui | D059828 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | metabolism |
| mesh[13].descriptor_name | Plant Cells |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D063245 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Plant Development |
| mesh[15].qualifier_ui | Q000235 |
| mesh[15].descriptor_ui | D011401 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | genetics |
| mesh[15].descriptor_name | Promoter Regions, Genetic |
| mesh[16].qualifier_ui | Q000166 |
| mesh[16].descriptor_ui | D012639 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | cytology |
| mesh[16].descriptor_name | Seeds |
| mesh[17].qualifier_ui | Q000166 |
| mesh[17].descriptor_ui | D013234 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | cytology |
| mesh[17].descriptor_name | Stem Cells |
| mesh[18].qualifier_ui | Q000166 |
| mesh[18].descriptor_ui | D017360 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | cytology |
| mesh[18].descriptor_name | Arabidopsis |
| mesh[19].qualifier_ui | Q000196 |
| mesh[19].descriptor_ui | D017360 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | embryology |
| mesh[19].descriptor_name | Arabidopsis |
| mesh[20].qualifier_ui | Q000201 |
| mesh[20].descriptor_ui | D017360 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | enzymology |
| mesh[20].descriptor_name | Arabidopsis |
| mesh[21].qualifier_ui | Q000378 |
| mesh[21].descriptor_ui | D029681 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | metabolism |
| mesh[21].descriptor_name | Arabidopsis Proteins |
| mesh[22].qualifier_ui | Q000378 |
| mesh[22].descriptor_ui | D002154 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | metabolism |
| mesh[22].descriptor_name | Calpain |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D002455 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Cell Division |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D049109 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Cell Proliferation |
| mesh[25].qualifier_ui | Q000378 |
| mesh[25].descriptor_ui | D002473 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | metabolism |
| mesh[25].descriptor_name | Cell Wall |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D018507 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Gene Expression Regulation, Developmental |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D018506 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Gene Expression Regulation, Plant |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D018519 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Meristem |
| mesh[29].qualifier_ui | Q000378 |
| mesh[29].descriptor_ui | D008870 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | metabolism |
| mesh[29].descriptor_name | Microtubules |
| mesh[30].qualifier_ui | |
| mesh[30].descriptor_ui | D010641 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | |
| mesh[30].descriptor_name | Phenotype |
| mesh[31].qualifier_ui | Q000378 |
| mesh[31].descriptor_ui | D059828 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | metabolism |
| mesh[31].descriptor_name | Plant Cells |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D063245 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Plant Development |
| mesh[33].qualifier_ui | Q000235 |
| mesh[33].descriptor_ui | D011401 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | genetics |
| mesh[33].descriptor_name | Promoter Regions, Genetic |
| mesh[34].qualifier_ui | Q000166 |
| mesh[34].descriptor_ui | D012639 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | cytology |
| mesh[34].descriptor_name | Seeds |
| mesh[35].qualifier_ui | Q000166 |
| mesh[35].descriptor_ui | D013234 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | cytology |
| mesh[35].descriptor_name | Stem Cells |
| type | article |
| title | Calpain-Mediated Positional Information Directs Cell Wall Orientation to Sustain Plant Stem Cell Activity, Growth and Development |
| biblio.issue | 9 |
| biblio.volume | 56 |
| biblio.last_page | 1866 |
| biblio.first_page | 1855 |
| topics[0].id | https://openalex.org/T10184 |
| topics[0].field.id | https://openalex.org/fields/11 |
| topics[0].field.display_name | Agricultural and Biological Sciences |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1110 |
| topics[0].subfield.display_name | Plant Science |
| topics[0].display_name | Plant Molecular Biology Research |
| topics[1].id | https://openalex.org/T12472 |
| topics[1].field.id | https://openalex.org/fields/11 |
| topics[1].field.display_name | Agricultural and Biological Sciences |
| topics[1].score | 0.9979000091552734 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1110 |
| topics[1].subfield.display_name | Plant Science |
| topics[1].display_name | Plant responses to water stress |
| topics[2].id | https://openalex.org/T11927 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9977999925613403 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Plant Reproductive Biology |
| funders[0].id | https://openalex.org/F4320308380 |
| funders[0].ror | https://ror.org/03v76x132 |
| funders[0].display_name | Yale University |
| is_xpac | False |
| apc_list.value | 2880 |
| apc_list.currency | USD |
| apc_list.value_usd | 2880 |
| apc_paid | |
| concepts[0].id | https://openalex.org/C95444343 |
| concepts[0].level | 1 |
| concepts[0].score | 0.8227397203445435 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q7141 |
| concepts[0].display_name | Cell biology |
| concepts[1].id | https://openalex.org/C126021549 |
| concepts[1].level | 3 |
| concepts[1].score | 0.8113090991973877 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q207604 |
| concepts[1].display_name | Meristem |
| concepts[2].id | https://openalex.org/C86803240 |
| concepts[2].level | 0 |
| concepts[2].score | 0.713585615158081 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[2].display_name | Biology |
| concepts[3].id | https://openalex.org/C2910790502 |
| concepts[3].level | 4 |
| concepts[3].score | 0.6703967452049255 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q862600 |
| concepts[3].display_name | Totipotent |
| concepts[4].id | https://openalex.org/C85813293 |
| concepts[4].level | 3 |
| concepts[4].score | 0.6344484090805054 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q188909 |
| concepts[4].display_name | Cell division |
| concepts[5].id | https://openalex.org/C145103041 |
| concepts[5].level | 3 |
| concepts[5].score | 0.5538581013679504 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1151519 |
| concepts[5].display_name | Embryonic stem cell |
| concepts[6].id | https://openalex.org/C62112901 |
| concepts[6].level | 2 |
| concepts[6].score | 0.5074388384819031 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q189159 |
| concepts[6].display_name | Cell growth |
| concepts[7].id | https://openalex.org/C28328180 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4939318299293518 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q48196 |
| concepts[7].display_name | Stem cell |
| concepts[8].id | https://openalex.org/C2779491563 |
| concepts[8].level | 4 |
| concepts[8].score | 0.48962312936782837 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q157892 |
| concepts[8].display_name | Arabidopsis |
| concepts[9].id | https://openalex.org/C148738053 |
| concepts[9].level | 3 |
| concepts[9].score | 0.4593534469604492 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q210861 |
| concepts[9].display_name | Cellular differentiation |
| concepts[10].id | https://openalex.org/C1491633281 |
| concepts[10].level | 2 |
| concepts[10].score | 0.43265578150749207 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7868 |
| concepts[10].display_name | Cell |
| concepts[11].id | https://openalex.org/C163952510 |
| concepts[11].level | 4 |
| concepts[11].score | 0.4203642010688782 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q5058196 |
| concepts[11].display_name | Cell fate determination |
| concepts[12].id | https://openalex.org/C54355233 |
| concepts[12].level | 1 |
| concepts[12].score | 0.3278670907020569 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[12].display_name | Genetics |
| concepts[13].id | https://openalex.org/C104317684 |
| concepts[13].level | 2 |
| concepts[13].score | 0.2461654245853424 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[13].display_name | Gene |
| concepts[14].id | https://openalex.org/C86339819 |
| concepts[14].level | 3 |
| concepts[14].score | 0.15140578150749207 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q407384 |
| concepts[14].display_name | Transcription factor |
| concepts[15].id | https://openalex.org/C143065580 |
| concepts[15].level | 3 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q3285695 |
| concepts[15].display_name | Mutant |
| keywords[0].id | https://openalex.org/keywords/cell-biology |
| keywords[0].score | 0.8227397203445435 |
| keywords[0].display_name | Cell biology |
| keywords[1].id | https://openalex.org/keywords/meristem |
| keywords[1].score | 0.8113090991973877 |
| keywords[1].display_name | Meristem |
| keywords[2].id | https://openalex.org/keywords/biology |
| keywords[2].score | 0.713585615158081 |
| keywords[2].display_name | Biology |
| keywords[3].id | https://openalex.org/keywords/totipotent |
| keywords[3].score | 0.6703967452049255 |
| keywords[3].display_name | Totipotent |
| keywords[4].id | https://openalex.org/keywords/cell-division |
| keywords[4].score | 0.6344484090805054 |
| keywords[4].display_name | Cell division |
| keywords[5].id | https://openalex.org/keywords/embryonic-stem-cell |
| keywords[5].score | 0.5538581013679504 |
| keywords[5].display_name | Embryonic stem cell |
| keywords[6].id | https://openalex.org/keywords/cell-growth |
| keywords[6].score | 0.5074388384819031 |
| keywords[6].display_name | Cell growth |
| keywords[7].id | https://openalex.org/keywords/stem-cell |
| keywords[7].score | 0.4939318299293518 |
| keywords[7].display_name | Stem cell |
| keywords[8].id | https://openalex.org/keywords/arabidopsis |
| keywords[8].score | 0.48962312936782837 |
| keywords[8].display_name | Arabidopsis |
| keywords[9].id | https://openalex.org/keywords/cellular-differentiation |
| keywords[9].score | 0.4593534469604492 |
| keywords[9].display_name | Cellular differentiation |
| keywords[10].id | https://openalex.org/keywords/cell |
| keywords[10].score | 0.43265578150749207 |
| keywords[10].display_name | Cell |
| keywords[11].id | https://openalex.org/keywords/cell-fate-determination |
| keywords[11].score | 0.4203642010688782 |
| keywords[11].display_name | Cell fate determination |
| keywords[12].id | https://openalex.org/keywords/genetics |
| keywords[12].score | 0.3278670907020569 |
| keywords[12].display_name | Genetics |
| keywords[13].id | https://openalex.org/keywords/gene |
| keywords[13].score | 0.2461654245853424 |
| keywords[13].display_name | Gene |
| keywords[14].id | https://openalex.org/keywords/transcription-factor |
| keywords[14].score | 0.15140578150749207 |
| keywords[14].display_name | Transcription factor |
| language | en |
| locations[0].id | doi:10.1093/pcp/pcv110 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S110997964 |
| locations[0].source.issn | 0032-0781, 1471-9053 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0032-0781 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Plant and Cell Physiology |
| locations[0].source.host_organization | https://openalex.org/P4310311648 |
| locations[0].source.host_organization_name | Oxford University Press |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310311648 |
| locations[0].license | |
| locations[0].pdf_url | https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Plant and Cell Physiology |
| locations[0].landing_page_url | https://doi.org/10.1093/pcp/pcv110 |
| locations[1].id | pmid:26220906 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Plant & cell physiology |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/26220906 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5059309575 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-6872-6463 |
| authorships[0].author.display_name | Zhe Liang |
| authorships[0].countries | NO |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I54108979 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Plant Sciences, Norwegian University of Life Sciences, PO Box 5003, N-1432 Ås, Norway |
| authorships[0].institutions[0].id | https://openalex.org/I54108979 |
| authorships[0].institutions[0].ror | https://ror.org/04a1mvv97 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I54108979 |
| authorships[0].institutions[0].country_code | NO |
| authorships[0].institutions[0].display_name | Norwegian University of Life Sciences |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Zhe Liang |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Plant Sciences, Norwegian University of Life Sciences, PO Box 5003, N-1432 Ås, Norway |
| authorships[1].author.id | https://openalex.org/A5111423803 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Roy C. Brown |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I79516672 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Biology, University of Louisiana, Lafayette, LA 70504, USA |
| authorships[1].institutions[0].id | https://openalex.org/I79516672 |
| authorships[1].institutions[0].ror | https://ror.org/01x8rc503 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I2799628689, https://openalex.org/I79516672 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of Louisiana at Lafayette |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Roy C. Brown |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Biology, University of Louisiana, Lafayette, LA 70504, USA |
| authorships[2].author.id | https://openalex.org/A5076442647 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-1834-6213 |
| authorships[2].author.display_name | Jennifer C. Fletcher |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210144282, https://openalex.org/I95457486 |
| authorships[2].affiliations[0].raw_affiliation_string | Plant Gene Expression Centre, USDA/UC-Berkeley, Albany, CA 94710, USA |
| authorships[2].institutions[0].id | https://openalex.org/I4210144282 |
| authorships[2].institutions[0].ror | https://ror.org/03rafms67 |
| authorships[2].institutions[0].type | government |
| authorships[2].institutions[0].lineage | https://openalex.org/I1312222531, https://openalex.org/I1336096307, https://openalex.org/I4210094889, https://openalex.org/I4210144282, https://openalex.org/I95457486 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Plant Gene Expression Center |
| authorships[2].institutions[1].id | https://openalex.org/I95457486 |
| authorships[2].institutions[1].ror | https://ror.org/01an7q238 |
| authorships[2].institutions[1].type | education |
| authorships[2].institutions[1].lineage | https://openalex.org/I95457486 |
| authorships[2].institutions[1].country_code | US |
| authorships[2].institutions[1].display_name | University of California, Berkeley |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jennifer C. Fletcher |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Plant Gene Expression Centre, USDA/UC-Berkeley, Albany, CA 94710, USA |
| authorships[3].author.id | https://openalex.org/A5068150410 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-9421-236X |
| authorships[3].author.display_name | Hilde-Gunn Opsahl-Sorteberg |
| authorships[3].countries | NO |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I54108979 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Plant Sciences, Norwegian University of Life Sciences, PO Box 5003, N-1432 Ås, Norway |
| authorships[3].institutions[0].id | https://openalex.org/I54108979 |
| authorships[3].institutions[0].ror | https://ror.org/04a1mvv97 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I54108979 |
| authorships[3].institutions[0].country_code | NO |
| authorships[3].institutions[0].display_name | Norwegian University of Life Sciences |
| authorships[3].author_position | last |
| authorships[3].raw_author_name | Hilde-Gunn Opsahl-Sorteberg |
| authorships[3].is_corresponding | True |
| authorships[3].raw_affiliation_strings | Department of Plant Sciences, Norwegian University of Life Sciences, PO Box 5003, N-1432 Ås, Norway |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdf |
| open_access.oa_status | bronze |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Calpain-Mediated Positional Information Directs Cell Wall Orientation to Sustain Plant Stem Cell Activity, Growth and Development |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10184 |
| primary_topic.field.id | https://openalex.org/fields/11 |
| primary_topic.field.display_name | Agricultural and Biological Sciences |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1110 |
| primary_topic.subfield.display_name | Plant Science |
| primary_topic.display_name | Plant Molecular Biology Research |
| related_works | https://openalex.org/W1988866218, https://openalex.org/W1975436314, https://openalex.org/W3135610434, https://openalex.org/W2040764540, https://openalex.org/W2297254013, https://openalex.org/W2009519731, https://openalex.org/W2041356725, https://openalex.org/W2057143267, https://openalex.org/W2979541362, https://openalex.org/W2165811783 |
| cited_by_count | 30 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 8 |
| counts_by_year[1].year | 2023 |
| counts_by_year[1].cited_by_count | 3 |
| counts_by_year[2].year | 2022 |
| counts_by_year[2].cited_by_count | 2 |
| counts_by_year[3].year | 2021 |
| counts_by_year[3].cited_by_count | 5 |
| counts_by_year[4].year | 2020 |
| counts_by_year[4].cited_by_count | 2 |
| counts_by_year[5].year | 2019 |
| counts_by_year[5].cited_by_count | 2 |
| counts_by_year[6].year | 2018 |
| counts_by_year[6].cited_by_count | 1 |
| counts_by_year[7].year | 2017 |
| counts_by_year[7].cited_by_count | 1 |
| counts_by_year[8].year | 2016 |
| counts_by_year[8].cited_by_count | 6 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1093/pcp/pcv110 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S110997964 |
| best_oa_location.source.issn | 0032-0781, 1471-9053 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0032-0781 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Plant and Cell Physiology |
| best_oa_location.source.host_organization | https://openalex.org/P4310311648 |
| best_oa_location.source.host_organization_name | Oxford University Press |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| best_oa_location.license | |
| best_oa_location.pdf_url | https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Plant and Cell Physiology |
| best_oa_location.landing_page_url | https://doi.org/10.1093/pcp/pcv110 |
| primary_location.id | doi:10.1093/pcp/pcv110 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S110997964 |
| primary_location.source.issn | 0032-0781, 1471-9053 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0032-0781 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Plant and Cell Physiology |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648 |
| primary_location.license | |
| primary_location.pdf_url | https://academic.oup.com/pcp/article-pdf/56/9/1855/17912806/pcv110.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Plant and Cell Physiology |
| primary_location.landing_page_url | https://doi.org/10.1093/pcp/pcv110 |
| publication_date | 2015-07-27 |
| publication_year | 2015 |
| referenced_works | https://openalex.org/W2109995704, https://openalex.org/W2129997424, https://openalex.org/W2078579597, https://openalex.org/W2134673854, https://openalex.org/W2002991335, https://openalex.org/W2086490962, https://openalex.org/W1989726653, https://openalex.org/W1998708845, https://openalex.org/W2031152175, https://openalex.org/W2025356320, https://openalex.org/W2065776621, https://openalex.org/W1758913211, https://openalex.org/W2141180158, https://openalex.org/W6703447467, https://openalex.org/W2149123972, https://openalex.org/W2116122104, https://openalex.org/W2080766313, https://openalex.org/W2122328487, https://openalex.org/W2164571708, https://openalex.org/W2171307112, https://openalex.org/W68863934, https://openalex.org/W2162258669, https://openalex.org/W3047083715, https://openalex.org/W2171358926, https://openalex.org/W1968079819, https://openalex.org/W1988095088, https://openalex.org/W2143606062, https://openalex.org/W2062376345, https://openalex.org/W2138464000, https://openalex.org/W1700776583, https://openalex.org/W1824928353, https://openalex.org/W2106701773, https://openalex.org/W2040758690, https://openalex.org/W2136231175, https://openalex.org/W2004425781, https://openalex.org/W2140692122, https://openalex.org/W1981040191, https://openalex.org/W1980630177, https://openalex.org/W2135202770, https://openalex.org/W2134005600, https://openalex.org/W2108891367, https://openalex.org/W2140728495, https://openalex.org/W2017384418, https://openalex.org/W2171244570, https://openalex.org/W2013055299, https://openalex.org/W2160416183, https://openalex.org/W2094623233, https://openalex.org/W2169423430, https://openalex.org/W2095915414, https://openalex.org/W2002115219, https://openalex.org/W2161060432, https://openalex.org/W2123507671, https://openalex.org/W1994009543, https://openalex.org/W2026929555, https://openalex.org/W2075178911, https://openalex.org/W1598809600, https://openalex.org/W2114370122, https://openalex.org/W2166038257, https://openalex.org/W2111631834, https://openalex.org/W2110014743, https://openalex.org/W2093230917, https://openalex.org/W2103300721, https://openalex.org/W2059341413, https://openalex.org/W2148290276, https://openalex.org/W2004276246, https://openalex.org/W2089888337, https://openalex.org/W2065942585, https://openalex.org/W2109836810, https://openalex.org/W2338023719, https://openalex.org/W2041062999 |
| referenced_works_count | 70 |
| abstract_inverted_index.A | 218 |
| abstract_inverted_index.a | 170, 240 |
| abstract_inverted_index.By | 141 |
| abstract_inverted_index.We | 66, 83 |
| abstract_inverted_index.in | 73, 94, 110, 138, 222, 246, 249 |
| abstract_inverted_index.is | 43, 71, 135 |
| abstract_inverted_index.of | 10, 78, 115 |
| abstract_inverted_index.on | 7, 235 |
| abstract_inverted_index.to | 51, 92, 127, 174, 205 |
| abstract_inverted_index.we | 147 |
| abstract_inverted_index.L1- | 150 |
| abstract_inverted_index.Our | 184 |
| abstract_inverted_index.The | 32 |
| abstract_inverted_index.WUS | 123 |
| abstract_inverted_index.and | 2, 18, 47, 53, 81, 106, 124, 132, 151, 179, 194, 198, 215, 238 |
| abstract_inverted_index.are | 30, 167 |
| abstract_inverted_index.can | 231 |
| abstract_inverted_index.few | 23 |
| abstract_inverted_index.for | 45, 172, 220, 244 |
| abstract_inverted_index.its | 233 |
| abstract_inverted_index.may | 189 |
| abstract_inverted_index.set | 180 |
| abstract_inverted_index.the | 8, 38, 62, 74, 98, 116, 202 |
| abstract_inverted_index.yet | 22 |
| abstract_inverted_index.DEK1 | 69, 89, 145, 173, 188, 221 |
| abstract_inverted_index.STM, | 125 |
| abstract_inverted_index.also | 136 |
| abstract_inverted_index.axis | 128 |
| abstract_inverted_index.cell | 4, 11, 15, 19, 56, 130, 143, 157, 191, 196, 209, 225, 229 |
| abstract_inverted_index.cues | 96 |
| abstract_inverted_index.data | 185 |
| abstract_inverted_index.dek1 | 139 |
| abstract_inverted_index.from | 97 |
| abstract_inverted_index.gene | 36 |
| abstract_inverted_index.link | 27 |
| abstract_inverted_index.more | 241 |
| abstract_inverted_index.role | 219 |
| abstract_inverted_index.show | 67, 85, 148 |
| abstract_inverted_index.stem | 3, 156, 208 |
| abstract_inverted_index.that | 25, 58, 68, 86, 149, 187 |
| abstract_inverted_index.wall | 20, 192, 226 |
| abstract_inverted_index.with | 14, 169 |
| abstract_inverted_index.PIN4, | 122 |
| abstract_inverted_index.These | 165 |
| abstract_inverted_index.WOX2, | 120 |
| abstract_inverted_index.being | 49 |
| abstract_inverted_index.cells | 77 |
| abstract_inverted_index.cues. | 183 |
| abstract_inverted_index.cycle | 16 |
| abstract_inverted_index.early | 111 |
| abstract_inverted_index.first | 99 |
| abstract_inverted_index.genes | 119 |
| abstract_inverted_index.leads | 91 |
| abstract_inverted_index.organ | 216 |
| abstract_inverted_index.plant | 40 |
| abstract_inverted_index.shoot | 161 |
| abstract_inverted_index.these | 28 |
| abstract_inverted_index.while | 211 |
| abstract_inverted_index.(DEK1) | 35 |
| abstract_inverted_index.ATML1, | 121 |
| abstract_inverted_index.allows | 59 |
| abstract_inverted_index.anchor | 190 |
| abstract_inverted_index.apical | 162 |
| abstract_inverted_index.beyond | 61 |
| abstract_inverted_index.cells, | 108 |
| abstract_inverted_index.cells. | 251 |
| abstract_inverted_index.confer | 52 |
| abstract_inverted_index.depend | 6 |
| abstract_inverted_index.direct | 175 |
| abstract_inverted_index.during | 228 |
| abstract_inverted_index.embryo | 64, 112 |
| abstract_inverted_index.events | 29 |
| abstract_inverted_index.growth | 214 |
| abstract_inverted_index.known. | 31 |
| abstract_inverted_index.mainly | 154 |
| abstract_inverted_index.marker | 118 |
| abstract_inverted_index.seeds, | 79 |
| abstract_inverted_index.severe | 160 |
| abstract_inverted_index.stage. | 65 |
| abstract_inverted_index.unique | 39 |
| abstract_inverted_index.KERNEL1 | 34 |
| abstract_inverted_index.affects | 155 |
| abstract_inverted_index.altered | 103, 137 |
| abstract_inverted_index.calpain | 41 |
| abstract_inverted_index.causing | 159 |
| abstract_inverted_index.changes | 93 |
| abstract_inverted_index.control | 5, 17, 195 |
| abstract_inverted_index.effects | 234 |
| abstract_inverted_index.explain | 232 |
| abstract_inverted_index.factors | 24 |
| abstract_inverted_index.further | 84 |
| abstract_inverted_index.general | 242 |
| abstract_inverted_index.growth, | 48 |
| abstract_inverted_index.highest | 72 |
| abstract_inverted_index.onward, | 102 |
| abstract_inverted_index.plant's | 203 |
| abstract_inverted_index.protein | 42 |
| abstract_inverted_index.related | 126 |
| abstract_inverted_index.results | 166 |
| abstract_inverted_index.sensing | 13 |
| abstract_inverted_index.suggest | 186 |
| abstract_inverted_index.thereby | 200 |
| abstract_inverted_index.zygotic | 100 |
| abstract_inverted_index.actively | 75 |
| abstract_inverted_index.calpains | 245 |
| abstract_inverted_index.cellular | 177 |
| abstract_inverted_index.directly | 26 |
| abstract_inverted_index.dividing | 76 |
| abstract_inverted_index.division | 101, 197, 230 |
| abstract_inverted_index.embryos. | 140 |
| abstract_inverted_index.encoding | 37 |
| abstract_inverted_index.function | 90, 243 |
| abstract_inverted_index.globular | 63 |
| abstract_inverted_index.identity | 57, 131 |
| abstract_inverted_index.maintain | 54, 206 |
| abstract_inverted_index.meristem | 133, 163 |
| abstract_inverted_index.patterns | 105 |
| abstract_inverted_index.suggests | 239 |
| abstract_inverted_index.DEFECTIVE | 33 |
| abstract_inverted_index.abortion. | 113 |
| abstract_inverted_index.balancing | 201 |
| abstract_inverted_index.directing | 213 |
| abstract_inverted_index.embryonic | 117, 236 |
| abstract_inverted_index.epidermal | 55 |
| abstract_inverted_index.essential | 50 |
| abstract_inverted_index.meristems | 80 |
| abstract_inverted_index.misshapen | 107 |
| abstract_inverted_index.positions | 193 |
| abstract_inverted_index.resulting | 109 |
| abstract_inverted_index.Eukaryotic | 0 |
| abstract_inverted_index.Expression | 114 |
| abstract_inverted_index.activities | 178 |
| abstract_inverted_index.consistent | 168 |
| abstract_inverted_index.downstream | 181 |
| abstract_inverted_index.eukaryotic | 250 |
| abstract_inverted_index.expression | 70 |
| abstract_inverted_index.formation. | 217 |
| abstract_inverted_index.functions, | 134, 158 |
| abstract_inverted_index.monitoring | 142 |
| abstract_inverted_index.positional | 12 |
| abstract_inverted_index.regulating | 223 |
| abstract_inverted_index.reservoirs | 210 |
| abstract_inverted_index.totipotent | 207 |
| abstract_inverted_index.35S-induced | 152 |
| abstract_inverted_index.Arabidopsis | 88 |
| abstract_inverted_index.development | 1, 46, 60 |
| abstract_inverted_index.eliminating | 87 |
| abstract_inverted_index.fundamental | 44 |
| abstract_inverted_index.integration | 9 |
| abstract_inverted_index.microtubule | 104, 247 |
| abstract_inverted_index.orientation | 227 |
| abstract_inverted_index.phenotypes. | 164 |
| abstract_inverted_index.requirement | 171, 204 |
| abstract_inverted_index.development, | 237 |
| abstract_inverted_index.organization | 248 |
| abstract_inverted_index.positioning, | 21 |
| abstract_inverted_index.vasculature. | 82 |
| abstract_inverted_index.developmental | 95, 182 |
| abstract_inverted_index.organization, | 129 |
| abstract_inverted_index.layer-specific | 144, 176 |
| abstract_inverted_index.simultaneously | 212 |
| abstract_inverted_index.down-regulation | 153 |
| abstract_inverted_index.differentiation, | 199 |
| abstract_inverted_index.down-regulation, | 146 |
| abstract_inverted_index.microtubule-orchestrated | 224 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5068150410 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 4 |
| corresponding_institution_ids | https://openalex.org/I54108979 |
| citation_normalized_percentile.value | 0.93506394 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |