Calprotectin as a Possible Biomarker in Various Lung Diseases Article Swipe
Maryam Abbas
,
Olumide Ijishakin
,
Shwetha Gopal
,
Iqra Saeed
,
Shilpa Arcot
,
Chidera Emmanuel Okezie
,
Gift Joanna Agbo
,
Victor Chiedozie Ezeamii
,
Omobolaji Samuel Ajayi
,
Ngozi Amanze
,
Sadam Alzaki
,
Tambi Isaac
,
Husna Shahnoor
,
Efe Okunzuwa
,
Amy Alfy
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.9734/jammr/2023/v35i225265
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.9734/jammr/2023/v35i225265
Calprotectin (CLP) comprises two calcium-binding proteins from the S-100 protein family, S100A8 and S100A9. CLP involves various cellular processes in lung health and disease, including anti-microbial functions, pro- and anti-tumor properties, angiogenesis, DNA damage response, and extracellular matrix remodeling. The systematic review explores the potential of calprotectin as a diagnostic and prognostic biomarker for various respiratory diseases. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and comprehensively searched electronic databases. Of 290 initially identified studies, 13 were included Olumide Ijishakin in the review, covering conditions such as cystic fibrosis (CF), lung cancer, COVID-19, asthma, and interstitial lung disease. For CF, fecal calprotectin showed promise as a non-invasive biomarker for diagnosing and monitoring pulmonary exacerbations. In lung cancer, calprotectin and other markers demonstrated potential for identifying high-risk individuals. In COVID-19, calprotectin levels were associated with disease severity and mortality risk. For asthma, calprotectin's role in neutrophil activation and neutrophilic asthma development was investigated. The review emphasizes the importance of robust biomarkers in improving disease management, reducing mortality rates, and enhancing patient care for respiratory conditions. Further research and validation studies are needed to establish the clinical utility of calprotectin as a biomarker for respiratory diseases.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.9734/jammr/2023/v35i225265
- https://journaljammr.com/index.php/JAMMR/article/download/5265/10497
- OA Status
- diamond
- References
- 32
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4388191467
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4388191467Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.9734/jammr/2023/v35i225265Digital Object Identifier
- Title
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Calprotectin as a Possible Biomarker in Various Lung DiseasesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-10-27Full publication date if available
- Authors
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Maryam Abbas, Olumide Ijishakin, Shwetha Gopal, Iqra Saeed, Shilpa Arcot, Chidera Emmanuel Okezie, Gift Joanna Agbo, Victor Chiedozie Ezeamii, Omobolaji Samuel Ajayi, Ngozi Amanze, Sadam Alzaki, Tambi Isaac, Husna Shahnoor, Efe Okunzuwa, Amy AlfyList of authors in order
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https://doi.org/10.9734/jammr/2023/v35i225265Publisher landing page
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https://journaljammr.com/index.php/JAMMR/article/download/5265/10497Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://journaljammr.com/index.php/JAMMR/article/download/5265/10497Direct OA link when available
- Concepts
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Calprotectin, Biomarker, Medicine, S100A9, Lung cancer, Disease, Asthma, S100A8, Internal medicine, Oncology, Immunology, Inflammatory bowel disease, Inflammation, Biology, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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32Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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