Candida–Epithelial Interactions Article Swipe
Related Concepts
Biology
Commensalism
Epithelium
Microbiology
Cell biology
Adhesion
Host (biology)
Bacteria
Ecology
Chemistry
Genetics
Organic chemistry
Jonathan P. Richardson
,
Jemima Ho
,
Julian R. Naglik
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3390/jof4010022
· OA: W2789533278
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3390/jof4010022
· OA: W2789533278
A plethora of intricate and dynamic molecular interactions occur between microbes and the epithelial cells that form the mucosal surfaces of the human body. Fungi, particularly species of Candida, are commensal members of our microbiota, continuously interacting with epithelial cells. Transient and localised perturbations to the mucosal environment can facilitate the overgrowth of fungi, causing infection. This minireview will examine the direct and indirect mechanisms by which Candida species and epithelial cells interact with each other, and explore the factors involved in the central processes of adhesion, invasion, and destruction of host mucosal surfaces.
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