Cannabinomics: Application of Metabolomics in Cannabis (Cannabis sativa L.) Research and Development Article Swipe
Konstantinos A. Aliferis
,
David Bernard-Perron
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.3389/fpls.2020.00554
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.3389/fpls.2020.00554
Cannabis (Cannabis sativa L.) is a complex, polymorphic plant species, which produces a vast array of bioactive metabolites, the two major chemical groups being cannabinoids and terpenoids. Nonetheless, the psychoactive cannabinoid tetrahydrocannabinol (Δ 9 -THC) and the non-psychoactive cannabidiol (CBD), are the two major cannabinoids that have monopolized the research interest. Currently, more than 600 Cannabis varieties are commercially available, providing access to a multitude of potent extracts with complex compositions, whose genetics are largely inconclusive. Recently introduced legislation on Cannabis cultivation in many countries represents a great opportunity, but at the same time, a great challenge for Cannabis research and development (R&D) toward applications in the pharmaceutical, food, cosmetics, and agrochemical industries. Based on its versatility and unique capabilities in the deconvolution of the metabolite composition of complex matrices, metabolomics represents an ideal bioanalytical tool that could greatly assist and accelerate Cannabis R&D. Among others, Cannabis metabolomics or cannabinomics can be applied in the taxonomy of Cannabis varieties in chemovars, the research on the discovery and assessment of new Cannabis-based sources of bioactivity in medicine, the development of new food products, and the optimization of its cultivation, aiming for improvements in yield and potency. Although Cannabis research is still in its infancy, it is highly foreseen that the employment of advanced metabolomics will provide insights that could assist the sector to face the aforementioned challenges. Within this context, here, the current state-of-the-art and conceptual aspects of cannabinomics are presented.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3389/fpls.2020.00554
- https://www.frontiersin.org/articles/10.3389/fpls.2020.00554/pdf
- OA Status
- gold
- Cited By
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- References
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- 10
- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W3023602865Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fpls.2020.00554Digital Object Identifier
- Title
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Cannabinomics: Application of Metabolomics in Cannabis (Cannabis sativa L.) Research and DevelopmentWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-05-08Full publication date if available
- Authors
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Konstantinos A. Aliferis, David Bernard-PerronList of authors in order
- Landing page
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https://doi.org/10.3389/fpls.2020.00554Publisher landing page
- PDF URL
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https://www.frontiersin.org/articles/10.3389/fpls.2020.00554/pdfDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/articles/10.3389/fpls.2020.00554/pdfDirect OA link when available
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Cannabis, Cannabidiol, Context (archaeology), Cannabis sativa, Biotechnology, Metabolomics, Biology, Medicine, Psychiatry, Bioinformatics, Paleontology, BotanyTop concepts (fields/topics) attached by OpenAlex
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94Total citation count in OpenAlex
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2025: 16, 2024: 23, 2023: 20, 2022: 17, 2021: 13Per-year citation counts (last 5 years)
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165Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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