Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE‐IT Article Swipe
Brian Olshansky
,
Deepak L. Bhatt
,
Michael Miller
,
Philippe Gabríel Steg
,
Eliot A. Brinton
,
Terry A. Jacobson
,
Steven B. Ketchum
,
Ralph T. Doyle
,
Rebecca A. Juliano
,
Lixia Jiao
,
Peter R. Kowey
,
James A. Reiffel
,
Jean‐Claude Tardif
,
Christie M. Ballantyne
,
Mina K. Chung
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1161/jaha.121.026756
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1161/jaha.121.026756
Background In REDUCE‐IT (Reduction of Cardiovascular Events With Icosapent Ethyl–Intervention Trial), icosapent ethyl (IPE) versus placebo) reduced cardiovascular death, myocardial infarction, stroke, coronary revascularization, or unstable angina requiring hospitalization, but was associated with increased atrial fibrillation/atrial flutter (AF) hospitalization (3.1% IPE versus 2.1% placebo; P =0.004). Methods and Results We performed post hoc efficacy and safety analyses of patients with or without prior AF (before randomization) and with or without in‐study time‐varying AF hospitalization to assess relationships of IPE (versus placebo) and outcomes. In‐study AF hospitalization event rates were higher in patients with prior AF (12.5% versus 6.3%, IPE versus placebo; P =0.007) versus without prior AF (2.2% versus 1.6%, IPE versus placebo; P =0.09). Serious bleeding rates trended higher in patients with (7.3% versus 6.0%, IPE versus placebo; P =0.59) versus without prior AF (2.3% versus 1.7%, IPE versus placebo; P =0.08). With IPE, serious bleeding trended higher regardless of prior AF (interaction P value [ P int ]=0.61) or postrandomization AF hospitalization ( P int =0.66). Patients with prior AF (n=751, 9.2%) versus without prior AF (n=7428, 90.8%) had similar relative risk reductions of the primary composite and key secondary composite end points with IPE versus placebo ( P int =0.37 and P int =0.55, respectively). Conclusions In REDUCE‐IT, in‐study AF hospitalization rates were higher in patients with prior AF especially in those randomized to IPE. Although serious bleeding trended higher in those randomized to IPE versus placebo over the course of the study, serious bleeding was not different regardless of prior AF or in‐study AF hospitalization. Patients with prior AF or in‐study AF hospitalization had consistent relative risk reductions across primary, key secondary, and stroke end points with IPE. Registration URL: https://clinicaltrials.gov/ct2/show/NCT01492361 ; Unique Identifier: NCT01492361
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1161/jaha.121.026756
- OA Status
- gold
- Cited By
- 23
- References
- 45
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4321455716
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4321455716Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1161/jaha.121.026756Digital Object Identifier
- Title
-
Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE‐ITWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-02-21Full publication date if available
- Authors
-
Brian Olshansky, Deepak L. Bhatt, Michael Miller, Philippe Gabríel Steg, Eliot A. Brinton, Terry A. Jacobson, Steven B. Ketchum, Ralph T. Doyle, Rebecca A. Juliano, Lixia Jiao, Peter R. Kowey, James A. Reiffel, Jean‐Claude Tardif, Christie M. Ballantyne, Mina K. ChungList of authors in order
- Landing page
-
https://doi.org/10.1161/jaha.121.026756Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1161/jaha.121.026756Direct OA link when available
- Concepts
-
Medicine, Atrial fibrillation, Placebo, Myocardial infarction, Internal medicine, Cardiology, Unstable angina, Stroke (engine), Atrial flutter, Coronary artery disease, Randomization, Randomized controlled trial, Post-hoc analysis, Pathology, Engineering, Alternative medicine, Mechanical engineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
23Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 8, 2024: 12, 2023: 3Per-year citation counts (last 5 years)
- References (count)
-
45Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4321455716 |
|---|---|
| doi | https://doi.org/10.1161/jaha.121.026756 |
| ids.doi | https://doi.org/10.1161/jaha.121.026756 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/36802845 |
| ids.openalex | https://openalex.org/W4321455716 |
| fwci | 5.98955228 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000188 |
| mesh[1].descriptor_ui | D001281 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | drug therapy |
| mesh[1].descriptor_name | Atrial Fibrillation |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D012307 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Risk Factors |
| mesh[3].qualifier_ui | Q000009 |
| mesh[3].descriptor_ui | D015118 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | adverse effects |
| mesh[3].descriptor_name | Eicosapentaenoic Acid |
| mesh[4].qualifier_ui | Q000453 |
| mesh[4].descriptor_ui | D020521 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | epidemiology |
| mesh[4].descriptor_name | Stroke |
| mesh[5].qualifier_ui | Q000209 |
| mesh[5].descriptor_ui | D020521 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | etiology |
| mesh[5].descriptor_name | Stroke |
| mesh[6].qualifier_ui | Q000517 |
| mesh[6].descriptor_ui | D020521 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | prevention & control |
| mesh[6].descriptor_name | Stroke |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D016896 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Treatment Outcome |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D006801 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Humans |
| mesh[9].qualifier_ui | Q000188 |
| mesh[9].descriptor_ui | D001281 |
| mesh[9].is_major_topic | True |
| mesh[9].qualifier_name | drug therapy |
| mesh[9].descriptor_name | Atrial Fibrillation |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D012307 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Risk Factors |
| mesh[11].qualifier_ui | Q000009 |
| mesh[11].descriptor_ui | D015118 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | adverse effects |
| mesh[11].descriptor_name | Eicosapentaenoic Acid |
| mesh[12].qualifier_ui | Q000453 |
| mesh[12].descriptor_ui | D020521 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | epidemiology |
| mesh[12].descriptor_name | Stroke |
| mesh[13].qualifier_ui | Q000209 |
| mesh[13].descriptor_ui | D020521 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | etiology |
| mesh[13].descriptor_name | Stroke |
| mesh[14].qualifier_ui | Q000517 |
| mesh[14].descriptor_ui | D020521 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | prevention & control |
| mesh[14].descriptor_name | Stroke |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D016896 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Treatment Outcome |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D006801 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Humans |
| mesh[17].qualifier_ui | Q000188 |
| mesh[17].descriptor_ui | D001281 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | drug therapy |
| mesh[17].descriptor_name | Atrial Fibrillation |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D012307 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Risk Factors |
| mesh[19].qualifier_ui | Q000009 |
| mesh[19].descriptor_ui | D015118 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | adverse effects |
| mesh[19].descriptor_name | Eicosapentaenoic Acid |
| mesh[20].qualifier_ui | Q000453 |
| mesh[20].descriptor_ui | D020521 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | epidemiology |
| mesh[20].descriptor_name | Stroke |
| mesh[21].qualifier_ui | Q000209 |
| mesh[21].descriptor_ui | D020521 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | etiology |
| mesh[21].descriptor_name | Stroke |
| mesh[22].qualifier_ui | Q000517 |
| mesh[22].descriptor_ui | D020521 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | prevention & control |
| mesh[22].descriptor_name | Stroke |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D016896 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Treatment Outcome |
| type | article |
| title | Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE‐IT |
| biblio.issue | 5 |
| biblio.volume | 12 |
| biblio.last_page | e026756 |
| biblio.first_page | e026756 |
| topics[0].id | https://openalex.org/T10387 |
| topics[0].field.id | https://openalex.org/fields/29 |
| topics[0].field.display_name | Nursing |
| topics[0].score | 0.9980999827384949 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2916 |
| topics[0].subfield.display_name | Nutrition and Dietetics |
| topics[0].display_name | Fatty Acid Research and Health |
| topics[1].id | https://openalex.org/T12910 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9850999712944031 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1303 |
| topics[1].subfield.display_name | Biochemistry |
| topics[1].display_name | Eicosanoids and Hypertension Pharmacology |
| topics[2].id | https://openalex.org/T12267 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9835000038146973 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2737 |
| topics[2].subfield.display_name | Physiology |
| topics[2].display_name | Diet and metabolism studies |
| is_xpac | False |
| apc_list.value | 2750 |
| apc_list.currency | USD |
| apc_list.value_usd | 2750 |
| apc_paid.value | 2750 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2750 |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9590206146240234 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2779161974 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7933657169342041 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q815819 |
| concepts[1].display_name | Atrial fibrillation |
| concepts[2].id | https://openalex.org/C27081682 |
| concepts[2].level | 3 |
| concepts[2].score | 0.7851691842079163 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q269829 |
| concepts[2].display_name | Placebo |
| concepts[3].id | https://openalex.org/C500558357 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6811628341674805 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q12152 |
| concepts[3].display_name | Myocardial infarction |
| concepts[4].id | https://openalex.org/C126322002 |
| concepts[4].level | 1 |
| concepts[4].score | 0.6451296806335449 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[4].display_name | Internal medicine |
| concepts[5].id | https://openalex.org/C164705383 |
| concepts[5].level | 1 |
| concepts[5].score | 0.6165781021118164 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q10379 |
| concepts[5].display_name | Cardiology |
| concepts[6].id | https://openalex.org/C2777785093 |
| concepts[6].level | 3 |
| concepts[6].score | 0.5857096910476685 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q2032041 |
| concepts[6].display_name | Unstable angina |
| concepts[7].id | https://openalex.org/C2780645631 |
| concepts[7].level | 2 |
| concepts[7].score | 0.552057683467865 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q671554 |
| concepts[7].display_name | Stroke (engine) |
| concepts[8].id | https://openalex.org/C2778292772 |
| concepts[8].level | 3 |
| concepts[8].score | 0.5327325463294983 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q1506572 |
| concepts[8].display_name | Atrial flutter |
| concepts[9].id | https://openalex.org/C2778213512 |
| concepts[9].level | 2 |
| concepts[9].score | 0.4302593469619751 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q844935 |
| concepts[9].display_name | Coronary artery disease |
| concepts[10].id | https://openalex.org/C204243189 |
| concepts[10].level | 3 |
| concepts[10].score | 0.4199592173099518 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q1363085 |
| concepts[10].display_name | Randomization |
| concepts[11].id | https://openalex.org/C168563851 |
| concepts[11].level | 2 |
| concepts[11].score | 0.41720354557037354 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q1436668 |
| concepts[11].display_name | Randomized controlled trial |
| concepts[12].id | https://openalex.org/C67761136 |
| concepts[12].level | 2 |
| concepts[12].score | 0.4121093451976776 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q2105849 |
| concepts[12].display_name | Post-hoc analysis |
| concepts[13].id | https://openalex.org/C142724271 |
| concepts[13].level | 1 |
| concepts[13].score | 0.0 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[13].display_name | Pathology |
| concepts[14].id | https://openalex.org/C127413603 |
| concepts[14].level | 0 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q11023 |
| concepts[14].display_name | Engineering |
| concepts[15].id | https://openalex.org/C204787440 |
| concepts[15].level | 2 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q188504 |
| concepts[15].display_name | Alternative medicine |
| concepts[16].id | https://openalex.org/C78519656 |
| concepts[16].level | 1 |
| concepts[16].score | 0.0 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q101333 |
| concepts[16].display_name | Mechanical engineering |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9590206146240234 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/atrial-fibrillation |
| keywords[1].score | 0.7933657169342041 |
| keywords[1].display_name | Atrial fibrillation |
| keywords[2].id | https://openalex.org/keywords/placebo |
| keywords[2].score | 0.7851691842079163 |
| keywords[2].display_name | Placebo |
| keywords[3].id | https://openalex.org/keywords/myocardial-infarction |
| keywords[3].score | 0.6811628341674805 |
| keywords[3].display_name | Myocardial infarction |
| keywords[4].id | https://openalex.org/keywords/internal-medicine |
| keywords[4].score | 0.6451296806335449 |
| keywords[4].display_name | Internal medicine |
| keywords[5].id | https://openalex.org/keywords/cardiology |
| keywords[5].score | 0.6165781021118164 |
| keywords[5].display_name | Cardiology |
| keywords[6].id | https://openalex.org/keywords/unstable-angina |
| keywords[6].score | 0.5857096910476685 |
| keywords[6].display_name | Unstable angina |
| keywords[7].id | https://openalex.org/keywords/stroke |
| keywords[7].score | 0.552057683467865 |
| keywords[7].display_name | Stroke (engine) |
| keywords[8].id | https://openalex.org/keywords/atrial-flutter |
| keywords[8].score | 0.5327325463294983 |
| keywords[8].display_name | Atrial flutter |
| keywords[9].id | https://openalex.org/keywords/coronary-artery-disease |
| keywords[9].score | 0.4302593469619751 |
| keywords[9].display_name | Coronary artery disease |
| keywords[10].id | https://openalex.org/keywords/randomization |
| keywords[10].score | 0.4199592173099518 |
| keywords[10].display_name | Randomization |
| keywords[11].id | https://openalex.org/keywords/randomized-controlled-trial |
| keywords[11].score | 0.41720354557037354 |
| keywords[11].display_name | Randomized controlled trial |
| keywords[12].id | https://openalex.org/keywords/post-hoc-analysis |
| keywords[12].score | 0.4121093451976776 |
| keywords[12].display_name | Post-hoc analysis |
| language | en |
| locations[0].id | doi:10.1161/jaha.121.026756 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2489920150 |
| locations[0].source.issn | 2047-9980 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2047-9980 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Journal of the American Heart Association |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_lineage_names | Wiley |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of the American Heart Association |
| locations[0].landing_page_url | https://doi.org/10.1161/jaha.121.026756 |
| locations[1].id | pmid:36802845 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of the American Heart Association |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/36802845 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:10111466 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | cc-by-nc-nd |
| locations[2].pdf_url | https://pmc.ncbi.nlm.nih.gov/articles/PMC10111466/pdf/JAH3-12-e026756.pdf |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | J Am Heart Assoc |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/10111466 |
| locations[3].id | pmh:oai:doaj.org/article:50b39d01ac344246a098267d5fb32c73 |
| locations[3].is_oa | False |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].license | |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 5 (2023) |
| locations[3].landing_page_url | https://doaj.org/article/50b39d01ac344246a098267d5fb32c73 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5030434846 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-6044-045X |
| authorships[0].author.display_name | Brian Olshansky |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I126307644 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Medicine University of Iowa Iowa City IA USA |
| authorships[0].institutions[0].id | https://openalex.org/I126307644 |
| authorships[0].institutions[0].ror | https://ror.org/036jqmy94 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I126307644 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | University of Iowa |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Brian Olshansky |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Medicine University of Iowa Iowa City IA USA |
| authorships[1].author.id | https://openalex.org/A5010571732 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-1278-6245 |
| authorships[1].author.display_name | Deepak L. Bhatt |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I1320796813, https://openalex.org/I98704320 |
| authorships[1].affiliations[0].raw_affiliation_string | Deepak L. Bhatt https://orcid.org/0000-0002-1278-6245 , Mount Sinai Heart, , Icahn School of Medicine at Mount Sinai Health System, , New York, , NY, , USA, |
| authorships[1].institutions[0].id | https://openalex.org/I98704320 |
| authorships[1].institutions[0].ror | https://ror.org/04a9tmd77 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I1320796813, https://openalex.org/I98704320 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Icahn School of Medicine at Mount Sinai |
| authorships[1].institutions[1].id | https://openalex.org/I1320796813 |
| authorships[1].institutions[1].ror | https://ror.org/04kfn4587 |
| authorships[1].institutions[1].type | healthcare |
| authorships[1].institutions[1].lineage | https://openalex.org/I1320796813 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | Mount Sinai Health System |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Deepak L. Bhatt |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Deepak L. Bhatt https://orcid.org/0000-0002-1278-6245 , Mount Sinai Heart, , Icahn School of Medicine at Mount Sinai Health System, , New York, , NY, , USA, |
| authorships[2].author.id | https://openalex.org/A5015234811 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-1679-2095 |
| authorships[2].author.display_name | Michael Miller |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I2799810409 |
| authorships[2].affiliations[0].raw_affiliation_string | Michael Miller https://orcid.org/0000-0002-1679-2095 , Department of Medicine, , Crescenz Veterans Affairs Medical Center and Hospital of the University of Pennsylvania, , Philadelphia, , PA, , USA, |
| authorships[2].institutions[0].id | https://openalex.org/I2799810409 |
| authorships[2].institutions[0].ror | https://ror.org/02917wp91 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I2799810409, https://openalex.org/I4210143392 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Hospital of the University of Pennsylvania |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Michael Miller |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Michael Miller https://orcid.org/0000-0002-1679-2095 , Department of Medicine, , Crescenz Veterans Affairs Medical Center and Hospital of the University of Pennsylvania, , Philadelphia, , PA, , USA, |
| authorships[3].author.id | https://openalex.org/A5003831287 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-6896-2941 |
| authorships[3].author.display_name | Philippe Gabríel Steg |
| authorships[3].countries | FR |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I4210145170, https://openalex.org/I4210166751 |
| authorships[3].affiliations[0].raw_affiliation_string | French Alliance for Cardiovascular Trials, Hôpital Bichat Paris France |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I154526488, https://openalex.org/I204730241, https://openalex.org/I4210097159 |
| authorships[3].affiliations[1].raw_affiliation_string | Assistance Publique‐Hôpitaux de Paris Université Paris–Cité, INSERM Unité Paris France |
| authorships[3].institutions[0].id | https://openalex.org/I4210166751 |
| authorships[3].institutions[0].ror | https://ror.org/05g3p2p60 |
| authorships[3].institutions[0].type | government |
| authorships[3].institutions[0].lineage | https://openalex.org/I4210166751 |
| authorships[3].institutions[0].country_code | FR |
| authorships[3].institutions[0].display_name | Alliance nationale pour les sciences de la vie et de la santé |
| authorships[3].institutions[1].id | https://openalex.org/I4210097159 |
| authorships[3].institutions[1].ror | https://ror.org/00pg5jh14 |
| authorships[3].institutions[1].type | healthcare |
| authorships[3].institutions[1].lineage | https://openalex.org/I4210097159 |
| authorships[3].institutions[1].country_code | FR |
| authorships[3].institutions[1].display_name | Assistance Publique – Hôpitaux de Paris |
| authorships[3].institutions[2].id | https://openalex.org/I4210145170 |
| authorships[3].institutions[2].ror | https://ror.org/03fdnmv92 |
| authorships[3].institutions[2].type | healthcare |
| authorships[3].institutions[2].lineage | https://openalex.org/I4210097159, https://openalex.org/I4210145170 |
| authorships[3].institutions[2].country_code | FR |
| authorships[3].institutions[2].display_name | Hôpital Bichat-Claude-Bernard |
| authorships[3].institutions[3].id | https://openalex.org/I154526488 |
| authorships[3].institutions[3].ror | https://ror.org/02vjkv261 |
| authorships[3].institutions[3].type | government |
| authorships[3].institutions[3].lineage | https://openalex.org/I154526488 |
| authorships[3].institutions[3].country_code | FR |
| authorships[3].institutions[3].display_name | Inserm |
| authorships[3].institutions[4].id | https://openalex.org/I204730241 |
| authorships[3].institutions[4].ror | https://ror.org/05f82e368 |
| authorships[3].institutions[4].type | education |
| authorships[3].institutions[4].lineage | https://openalex.org/I204730241 |
| authorships[3].institutions[4].country_code | FR |
| authorships[3].institutions[4].display_name | Université Paris Cité |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Ph. Gabriel Steg |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Assistance Publique‐Hôpitaux de Paris Université Paris–Cité, INSERM Unité Paris France, French Alliance for Cardiovascular Trials, Hôpital Bichat Paris France |
| authorships[4].author.id | https://openalex.org/A5020230532 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-9807-4010 |
| authorships[4].author.display_name | Eliot A. Brinton |
| authorships[4].affiliations[0].raw_affiliation_string | Eliot A. Brinton https://orcid.org/0000-0002-9807-4010 , Utah Lipid Center, , Salt Lake City, , UT, , USA, |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Eliot A. Brinton |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Eliot A. Brinton https://orcid.org/0000-0002-9807-4010 , Utah Lipid Center, , Salt Lake City, , UT, , USA, |
| authorships[5].author.id | https://openalex.org/A5084230583 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-9926-2179 |
| authorships[5].author.display_name | Terry A. Jacobson |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I150468666 |
| authorships[5].affiliations[0].raw_affiliation_string | Terry A. Jacobson https://orcid.org/0000-0002-9926-2179 , Lipid Clinic and Cardiovascular Risk Reduction Program, Department of Medicine, , Emory University School of Medicine, , Atlanta, , GA, , USA, |
| authorships[5].institutions[0].id | https://openalex.org/I150468666 |
| authorships[5].institutions[0].ror | https://ror.org/03czfpz43 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I150468666 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Emory University |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Terry A. Jacobson |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Terry A. Jacobson https://orcid.org/0000-0002-9926-2179 , Lipid Clinic and Cardiovascular Risk Reduction Program, Department of Medicine, , Emory University School of Medicine, , Atlanta, , GA, , USA, |
| authorships[6].author.id | https://openalex.org/A5061372345 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-9302-4743 |
| authorships[6].author.display_name | Steven B. Ketchum |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210130338 |
| authorships[6].affiliations[0].raw_affiliation_string | Steven B. Ketchum https://orcid.org/0000-0002-9302-4743 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[6].institutions[0].id | https://openalex.org/I4210130338 |
| authorships[6].institutions[0].ror | https://ror.org/0353d6x38 |
| authorships[6].institutions[0].type | company |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210113585, https://openalex.org/I4210130338 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Amarin (United States) |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Steven B. Ketchum |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Steven B. Ketchum https://orcid.org/0000-0002-9302-4743 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[7].author.id | https://openalex.org/A5012896274 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | Ralph T. Doyle |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I4210130338 |
| authorships[7].affiliations[0].raw_affiliation_string | Ralph T. DoyleJr https://orcid.org/0000-0003-4068-7778 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[7].institutions[0].id | https://openalex.org/I4210130338 |
| authorships[7].institutions[0].ror | https://ror.org/0353d6x38 |
| authorships[7].institutions[0].type | company |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210113585, https://openalex.org/I4210130338 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Amarin (United States) |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Ralph T. Doyle |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Ralph T. DoyleJr https://orcid.org/0000-0003-4068-7778 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[8].author.id | https://openalex.org/A5072532905 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-3714-6084 |
| authorships[8].author.display_name | Rebecca A. Juliano |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I4210130338 |
| authorships[8].affiliations[0].raw_affiliation_string | Rebecca A. Juliano https://orcid.org/0000-0002-3714-6084 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[8].institutions[0].id | https://openalex.org/I4210130338 |
| authorships[8].institutions[0].ror | https://ror.org/0353d6x38 |
| authorships[8].institutions[0].type | company |
| authorships[8].institutions[0].lineage | https://openalex.org/I4210113585, https://openalex.org/I4210130338 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Amarin (United States) |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Rebecca A. Juliano |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Rebecca A. Juliano https://orcid.org/0000-0002-3714-6084 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[9].author.id | https://openalex.org/A5055540639 |
| authorships[9].author.orcid | https://orcid.org/0000-0001-7003-4925 |
| authorships[9].author.display_name | Lixia Jiao |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I4210130338 |
| authorships[9].affiliations[0].raw_affiliation_string | Lixia Jiao https://orcid.org/0000-0001-7003-4925 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[9].institutions[0].id | https://openalex.org/I4210130338 |
| authorships[9].institutions[0].ror | https://ror.org/0353d6x38 |
| authorships[9].institutions[0].type | company |
| authorships[9].institutions[0].lineage | https://openalex.org/I4210113585, https://openalex.org/I4210130338 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | Amarin (United States) |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Lixia Jiao |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Lixia Jiao https://orcid.org/0000-0001-7003-4925 , Amarin Pharma, Inc., , Bridgewater, , NJ, , USA, |
| authorships[10].author.id | https://openalex.org/A5001241147 |
| authorships[10].author.orcid | https://orcid.org/0000-0001-7189-1638 |
| authorships[10].author.display_name | Peter R. Kowey |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I182321934 |
| authorships[10].affiliations[0].raw_affiliation_string | Peter R. Kowey https://orcid.org/0000-0001-7189-1638 , Lankenau Institute for Medical Research, , Wynnewood, , PA, , USA, |
| authorships[10].institutions[0].id | https://openalex.org/I182321934 |
| authorships[10].institutions[0].ror | https://ror.org/030g3hg75 |
| authorships[10].institutions[0].type | nonprofit |
| authorships[10].institutions[0].lineage | https://openalex.org/I182321934 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | Lankenau Institute for Medical Research |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Peter R. Kowey |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Peter R. Kowey https://orcid.org/0000-0001-7189-1638 , Lankenau Institute for Medical Research, , Wynnewood, , PA, , USA, |
| authorships[11].author.id | https://openalex.org/A5055404194 |
| authorships[11].author.orcid | https://orcid.org/0000-0001-5505-1866 |
| authorships[11].author.display_name | James A. Reiffel |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I78577930 |
| authorships[11].affiliations[0].raw_affiliation_string | James A. Reiffel https://orcid.org/0000-0001-5505-1866 , Columbia University Vagelos College of Physicians & Surgeons, , New York, , NY, , USA, |
| authorships[11].institutions[0].id | https://openalex.org/I78577930 |
| authorships[11].institutions[0].ror | https://ror.org/00hj8s172 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I78577930 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | Columbia University |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | James A. Reiffel |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | James A. Reiffel https://orcid.org/0000-0001-5505-1866 , Columbia University Vagelos College of Physicians & Surgeons, , New York, , NY, , USA, |
| authorships[12].author.id | https://openalex.org/A5049309607 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-8200-8983 |
| authorships[12].author.display_name | Jean‐Claude Tardif |
| authorships[12].countries | CA |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I2800290161, https://openalex.org/I70931966 |
| authorships[12].affiliations[0].raw_affiliation_string | Montreal Heart Institute, Université de Montréal Montreal Quebec Canada |
| authorships[12].institutions[0].id | https://openalex.org/I2800290161 |
| authorships[12].institutions[0].ror | https://ror.org/03vs03g62 |
| authorships[12].institutions[0].type | healthcare |
| authorships[12].institutions[0].lineage | https://openalex.org/I2800290161 |
| authorships[12].institutions[0].country_code | CA |
| authorships[12].institutions[0].display_name | Montreal Heart Institute |
| authorships[12].institutions[1].id | https://openalex.org/I70931966 |
| authorships[12].institutions[1].ror | https://ror.org/0161xgx34 |
| authorships[12].institutions[1].type | education |
| authorships[12].institutions[1].lineage | https://openalex.org/I70931966 |
| authorships[12].institutions[1].country_code | CA |
| authorships[12].institutions[1].display_name | Université de Montréal |
| authorships[12].author_position | middle |
| authorships[12].raw_author_name | Jean‐Claude Tardif |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Montreal Heart Institute, Université de Montréal Montreal Quebec Canada |
| authorships[13].author.id | https://openalex.org/A5052604218 |
| authorships[13].author.orcid | https://orcid.org/0000-0002-6432-1730 |
| authorships[13].author.display_name | Christie M. Ballantyne |
| authorships[13].countries | US |
| authorships[13].affiliations[0].institution_ids | https://openalex.org/I181547552 |
| authorships[13].affiliations[0].raw_affiliation_string | Christie M. Ballantyne https://orcid.org/0000-0002-6432-1730 , Department of Medicine, , Baylor College of Medicine, , Houston, , TX, , USA, |
| authorships[13].institutions[0].id | https://openalex.org/I181547552 |
| authorships[13].institutions[0].ror | https://ror.org/02pttbw34 |
| authorships[13].institutions[0].type | education |
| authorships[13].institutions[0].lineage | https://openalex.org/I181547552, https://openalex.org/I2801539370 |
| authorships[13].institutions[0].country_code | US |
| authorships[13].institutions[0].display_name | Baylor College of Medicine |
| authorships[13].author_position | middle |
| authorships[13].raw_author_name | Christie M. Ballantyne |
| authorships[13].is_corresponding | False |
| authorships[13].raw_affiliation_strings | Christie M. Ballantyne https://orcid.org/0000-0002-6432-1730 , Department of Medicine, , Baylor College of Medicine, , Houston, , TX, , USA, |
| authorships[14].author.id | https://openalex.org/A5084723768 |
| authorships[14].author.orcid | |
| authorships[14].author.display_name | Mina K. Chung |
| authorships[14].countries | US |
| authorships[14].affiliations[0].institution_ids | https://openalex.org/I1316902750 |
| authorships[14].affiliations[0].raw_affiliation_string | Mina K. Chung https://orcid.org/0000-0002-7835-6045 , Cleveland Clinic, , Cleveland, , OH, , USA, |
| authorships[14].institutions[0].id | https://openalex.org/I1316902750 |
| authorships[14].institutions[0].ror | https://ror.org/03xjacd83 |
| authorships[14].institutions[0].type | healthcare |
| authorships[14].institutions[0].lineage | https://openalex.org/I1316902750 |
| authorships[14].institutions[0].country_code | US |
| authorships[14].institutions[0].display_name | Cleveland Clinic |
| authorships[14].author_position | last |
| authorships[14].raw_author_name | Mina K. Chung |
| authorships[14].is_corresponding | False |
| authorships[14].raw_affiliation_strings | Mina K. Chung https://orcid.org/0000-0002-7835-6045 , Cleveland Clinic, , Cleveland, , OH, , USA, |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1161/jaha.121.026756 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE‐IT |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10387 |
| primary_topic.field.id | https://openalex.org/fields/29 |
| primary_topic.field.display_name | Nursing |
| primary_topic.score | 0.9980999827384949 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2916 |
| primary_topic.subfield.display_name | Nutrition and Dietetics |
| primary_topic.display_name | Fatty Acid Research and Health |
| related_works | https://openalex.org/W2113585844, https://openalex.org/W2916669046, https://openalex.org/W2802841177, https://openalex.org/W2120413119, https://openalex.org/W2047263140, https://openalex.org/W2518330835, https://openalex.org/W2182025991, https://openalex.org/W2808283081, https://openalex.org/W2985139050, https://openalex.org/W1978093411 |
| cited_by_count | 23 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 8 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 12 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 3 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1161/jaha.121.026756 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2489920150 |
| best_oa_location.source.issn | 2047-9980 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2047-9980 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Journal of the American Heart Association |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_lineage_names | Wiley |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of the American Heart Association |
| best_oa_location.landing_page_url | https://doi.org/10.1161/jaha.121.026756 |
| primary_location.id | doi:10.1161/jaha.121.026756 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2489920150 |
| primary_location.source.issn | 2047-9980 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2047-9980 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Journal of the American Heart Association |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_lineage_names | Wiley |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of the American Heart Association |
| primary_location.landing_page_url | https://doi.org/10.1161/jaha.121.026756 |
| publication_date | 2023-02-21 |
| publication_year | 2023 |
| referenced_works | https://openalex.org/W3043699463, https://openalex.org/W2597054569, https://openalex.org/W1973205627, https://openalex.org/W2106700467, https://openalex.org/W2169902118, https://openalex.org/W2980504792, https://openalex.org/W107170187, https://openalex.org/W2746828737, https://openalex.org/W2900347721, https://openalex.org/W2899669642, https://openalex.org/W2969391566, https://openalex.org/W2920910705, https://openalex.org/W2998055502, https://openalex.org/W2598498016, https://openalex.org/W2985476501, https://openalex.org/W3148697671, https://openalex.org/W3091209026, https://openalex.org/W2936852091, https://openalex.org/W3115888582, https://openalex.org/W3094072653, https://openalex.org/W3203721135, https://openalex.org/W2091494523, https://openalex.org/W2031234916, https://openalex.org/W1275357281, https://openalex.org/W2025462569, https://openalex.org/W2553507350, https://openalex.org/W2169828142, https://openalex.org/W2053800803, https://openalex.org/W2158784397, https://openalex.org/W2124458610, https://openalex.org/W2094999733, https://openalex.org/W1975997252, https://openalex.org/W2052111435, https://openalex.org/W2037769333, https://openalex.org/W2098841802, https://openalex.org/W2027175184, https://openalex.org/W2052715358, https://openalex.org/W1972060045, https://openalex.org/W2136386621, https://openalex.org/W2058047603, https://openalex.org/W2994308405, https://openalex.org/W3136726675, https://openalex.org/W3099468740, https://openalex.org/W4206763397, https://openalex.org/W3103257019 |
| referenced_works_count | 45 |
| abstract_inverted_index.( | 164, 199 |
| abstract_inverted_index.; | 285 |
| abstract_inverted_index.P | 44, 101, 113, 129, 141, 154, 157, 165, 200, 204 |
| abstract_inverted_index.[ | 156 |
| abstract_inverted_index.AF | 63, 72, 84, 94, 106, 134, 152, 162, 171, 177, 212, 221, 254, 257, 262, 265 |
| abstract_inverted_index.In | 1, 209 |
| abstract_inverted_index.We | 49 |
| abstract_inverted_index.in | 90, 120, 217, 223, 233 |
| abstract_inverted_index.of | 4, 57, 77, 150, 185, 243, 252 |
| abstract_inverted_index.or | 24, 60, 68, 160, 255, 263 |
| abstract_inverted_index.to | 74, 226, 236 |
| abstract_inverted_index.IPE | 40, 78, 98, 110, 126, 138, 196, 237 |
| abstract_inverted_index.and | 47, 54, 66, 81, 189, 203, 276 |
| abstract_inverted_index.but | 29 |
| abstract_inverted_index.end | 193, 278 |
| abstract_inverted_index.had | 180, 267 |
| abstract_inverted_index.hoc | 52 |
| abstract_inverted_index.int | 158, 166, 201, 205 |
| abstract_inverted_index.key | 190, 274 |
| abstract_inverted_index.not | 249 |
| abstract_inverted_index.the | 186, 241, 244 |
| abstract_inverted_index.was | 30, 248 |
| abstract_inverted_index.(AF) | 37 |
| abstract_inverted_index.2.1% | 42 |
| abstract_inverted_index.IPE, | 144 |
| abstract_inverted_index.IPE. | 227, 281 |
| abstract_inverted_index.URL: | 283 |
| abstract_inverted_index.With | 7, 143 |
| abstract_inverted_index.over | 240 |
| abstract_inverted_index.post | 51 |
| abstract_inverted_index.risk | 183, 270 |
| abstract_inverted_index.were | 88, 215 |
| abstract_inverted_index.with | 32, 59, 67, 92, 122, 169, 195, 219, 260, 280 |
| abstract_inverted_index.(2.2% | 107 |
| abstract_inverted_index.(2.3% | 135 |
| abstract_inverted_index.(3.1% | 39 |
| abstract_inverted_index.(7.3% | 123 |
| abstract_inverted_index.(IPE) | 13 |
| abstract_inverted_index.1.6%, | 109 |
| abstract_inverted_index.1.7%, | 137 |
| abstract_inverted_index.6.0%, | 125 |
| abstract_inverted_index.6.3%, | 97 |
| abstract_inverted_index.9.2%) | 173 |
| abstract_inverted_index.=0.37 | 202 |
| abstract_inverted_index.ethyl | 12 |
| abstract_inverted_index.event | 86 |
| abstract_inverted_index.prior | 62, 93, 105, 133, 151, 170, 176, 220, 253, 261 |
| abstract_inverted_index.rates | 87, 117, 214 |
| abstract_inverted_index.those | 224, 234 |
| abstract_inverted_index.value | 155 |
| abstract_inverted_index.(12.5% | 95 |
| abstract_inverted_index.90.8%) | 179 |
| abstract_inverted_index.=0.55, | 206 |
| abstract_inverted_index.=0.59) | 130 |
| abstract_inverted_index.Events | 6 |
| abstract_inverted_index.Unique | 286 |
| abstract_inverted_index.across | 272 |
| abstract_inverted_index.angina | 26 |
| abstract_inverted_index.assess | 75 |
| abstract_inverted_index.atrial | 34 |
| abstract_inverted_index.course | 242 |
| abstract_inverted_index.death, | 18 |
| abstract_inverted_index.higher | 89, 119, 148, 216, 232 |
| abstract_inverted_index.points | 194, 279 |
| abstract_inverted_index.safety | 55 |
| abstract_inverted_index.stroke | 277 |
| abstract_inverted_index.study, | 245 |
| abstract_inverted_index.versus | 14, 41, 96, 99, 103, 108, 111, 124, 127, 131, 136, 139, 174, 197, 238 |
| abstract_inverted_index.(before | 64 |
| abstract_inverted_index.(n=751, | 172 |
| abstract_inverted_index.(versus | 79 |
| abstract_inverted_index.=0.007) | 102 |
| abstract_inverted_index.=0.08). | 142 |
| abstract_inverted_index.=0.09). | 114 |
| abstract_inverted_index.=0.66). | 167 |
| abstract_inverted_index.Methods | 46 |
| abstract_inverted_index.Results | 48 |
| abstract_inverted_index.Serious | 115 |
| abstract_inverted_index.Trial), | 10 |
| abstract_inverted_index.]=0.61) | 159 |
| abstract_inverted_index.flutter | 36 |
| abstract_inverted_index.placebo | 198, 239 |
| abstract_inverted_index.primary | 187 |
| abstract_inverted_index.reduced | 16 |
| abstract_inverted_index.serious | 145, 229, 246 |
| abstract_inverted_index.similar | 181 |
| abstract_inverted_index.stroke, | 21 |
| abstract_inverted_index.trended | 118, 147, 231 |
| abstract_inverted_index.without | 61, 69, 104, 132, 175 |
| abstract_inverted_index.(n=7428, | 178 |
| abstract_inverted_index.=0.004). | 45 |
| abstract_inverted_index.Although | 228 |
| abstract_inverted_index.Patients | 168, 259 |
| abstract_inverted_index.analyses | 56 |
| abstract_inverted_index.bleeding | 116, 146, 230, 247 |
| abstract_inverted_index.coronary | 22 |
| abstract_inverted_index.efficacy | 53 |
| abstract_inverted_index.patients | 58, 91, 121, 218 |
| abstract_inverted_index.placebo) | 15, 80 |
| abstract_inverted_index.placebo; | 43, 100, 112, 128, 140 |
| abstract_inverted_index.primary, | 273 |
| abstract_inverted_index.relative | 182, 269 |
| abstract_inverted_index.unstable | 25 |
| abstract_inverted_index.Icosapent | 8 |
| abstract_inverted_index.composite | 188, 192 |
| abstract_inverted_index.different | 250 |
| abstract_inverted_index.icosapent | 11 |
| abstract_inverted_index.increased | 33 |
| abstract_inverted_index.outcomes. | 82 |
| abstract_inverted_index.performed | 50 |
| abstract_inverted_index.requiring | 27 |
| abstract_inverted_index.secondary | 191 |
| abstract_inverted_index.(Reduction | 3 |
| abstract_inverted_index.Background | 0 |
| abstract_inverted_index.In‐study | 83 |
| abstract_inverted_index.associated | 31 |
| abstract_inverted_index.consistent | 268 |
| abstract_inverted_index.especially | 222 |
| abstract_inverted_index.in‐study | 70, 211, 256, 264 |
| abstract_inverted_index.myocardial | 19 |
| abstract_inverted_index.randomized | 225, 235 |
| abstract_inverted_index.reductions | 184, 271 |
| abstract_inverted_index.regardless | 149, 251 |
| abstract_inverted_index.secondary, | 275 |
| abstract_inverted_index.Conclusions | 208 |
| abstract_inverted_index.Identifier: | 287 |
| abstract_inverted_index.NCT01492361 | 288 |
| abstract_inverted_index.REDUCE‐IT | 2 |
| abstract_inverted_index.infarction, | 20 |
| abstract_inverted_index.(interaction | 153 |
| abstract_inverted_index.REDUCE‐IT, | 210 |
| abstract_inverted_index.Registration | 282 |
| abstract_inverted_index.relationships | 76 |
| abstract_inverted_index.Cardiovascular | 5 |
| abstract_inverted_index.cardiovascular | 17 |
| abstract_inverted_index.randomization) | 65 |
| abstract_inverted_index.respectively). | 207 |
| abstract_inverted_index.time‐varying | 71 |
| abstract_inverted_index.hospitalization | 38, 73, 85, 163, 213, 266 |
| abstract_inverted_index.hospitalization, | 28 |
| abstract_inverted_index.hospitalization. | 258 |
| abstract_inverted_index.postrandomization | 161 |
| abstract_inverted_index.revascularization, | 23 |
| abstract_inverted_index.fibrillation/atrial | 35 |
| abstract_inverted_index.Ethyl–Intervention | 9 |
| abstract_inverted_index.https://clinicaltrials.gov/ct2/show/NCT01492361 | 284 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 96 |
| countries_distinct_count | 3 |
| institutions_distinct_count | 15 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8500000238418579 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.95197859 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |