Certainty and uncertainty in the biological activities of resveratrol Article Swipe
Lorenzo Drago
,
Giorgio Ciprandi
,
Giulia Brindisi
,
Francesco Paolo Brunese
,
Giulio Dinardo
,
Alessandra Gori
,
Cristiana Indolfi
,
Matteo Naso
,
Enrico Tondina
,
Chiara Trincianti
,
Attilio Varricchio
,
Anna Maria Zicari
,
Hammad Ullah
,
Maria Daglia
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/fft2.375
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/fft2.375
Resveratrol is a nonflavonoid polyphenolic compound with a chemical structure consisting of two aromatic rings linked by a methylene bridge. It exists in two primary isomers and has a broad range of desirable biological activities, including antioxidant, anti‐inflammatory, antidiabetic, cardioprotective, and antitumor activities. Some antioxidant properties of resveratrol are known with certainty, such as its potential to positively impact cardiovascular health, inflammation, and the metabolism. On the other hand, many uncertainties and controversies plague its efficacy, including issues related to its bioavailability, dosing, human clinical trial results, interactions with other food components and drugs, and individual variability. In brief, although promising results have been observed in in vitro and in vivo studies, the translation of these findings to human health remains uncertain. Many human clinical trials on resveratrol are ongoing or have proven inconclusive, making it challenging to definitively determine its efficacy for specific health conditions and its dose and duration of treatment. Resveratrol may interact with medications and have varying effects on individuals. In conclusion, it is essential to approach resveratrol with a balanced perspective, consulting with healthcare professionals, and considering the evolving scientific evidence when making decisions regarding its clinical use.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/fft2.375
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fft2.375
- OA Status
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- Cited By
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All OpenAlex metadata
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https://doi.org/10.1002/fft2.375Digital Object Identifier
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Certainty and uncertainty in the biological activities of resveratrolWork title
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articleOpenAlex work type
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enPrimary language
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2024Year of publication
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2024-03-26Full publication date if available
- Authors
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Lorenzo Drago, Giorgio Ciprandi, Giulia Brindisi, Francesco Paolo Brunese, Giulio Dinardo, Alessandra Gori, Cristiana Indolfi, Matteo Naso, Enrico Tondina, Chiara Trincianti, Attilio Varricchio, Anna Maria Zicari, Hammad Ullah, Maria DagliaList of authors in order
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https://doi.org/10.1002/fft2.375Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fft2.375Direct link to full text PDF
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goldOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/fft2.375Direct OA link when available
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Certainty, Resveratrol, Medicine, Epistemology, Philosophy, PharmacologyTop concepts (fields/topics) attached by OpenAlex
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2025: 7, 2024: 7Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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