Microfluidic fabrication technologies are increasingly used to produce functional anisotropic microstructures for broad applications. However, the limited flow manipulation methods hinder the production of intricate microstructure morphologies. In this work, we introduce CeyeHao, an artificial intelligence–driven flow programming methodology for designing microchannels to perform unprecedented flow manipulations. In CeyeHao, microchannels containing hierarchically assembled obstacles are constructed, offering more…