Clinical and Experimental Medicine • Vol 25 • No 1
Changes in CD4+ T cells subsets in patients with alcohol-related cirrhosis
January 2025 • Paola Zuluaga, Coral Zurera-Egea, Daniel G. Fuster, Anna Hernández‐Rubio, Aina Teniente‐Serra, Eva Martínez‐Cáceres, Roberto Muga
Abstract Alcohol-related cirrhosis (AC) is a condition that impacts in immunity. We analyzed changes over time in CD4 + subsets in AC-patients. We included patients with alcohol use disorder admitted at least twice for treatment. Patients without evidence of liver disease were the control group (CG). We analyzed naïve, memory, TEMRA, Th1, Th2, Th17, early activated, and late activated subsets. During the follow-up, TEMRA T cells were increased (1.2 ± 1.1% vs. 2.1 ± 1.1%, p = 0.03) in AC-patients ( n = 5) and Th17 …