Changes in Heart Rate and Its Regulation by the Autonomic Nervous System Do Not Differ Between Forced and Voluntary Exercise in Mice Article Swipe
Robert Lakin
,
Camilo Guzmán
,
Farzad Izaddoustdar
,
Nazari Polidovitch
,
Jack M. Goodman
,
Peter H. Backx
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3389/fphys.2018.00841
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.3389/fphys.2018.00841
-No previous mouse studies have compared the effects of forced and voluntary exercise on the heart function and its modulation by the autonomic nervous system (ANS).-Both voluntary free-wheel running and forced swimming induced similar improvements in ventricular contractile function, reductions in heart rate (HR) and enhancements of HR variability (HRV).-HR regulation in exercised mice was linked to increased parasympathetic nerve activity and reduced sympathetic nerve activity.- HRV was independent of HR and depended primarily on PNA in both exercised and sedentary mice.- Complete cardiac autonomic blockade eliminated differences in both HR and HRV between exercised and sedentary mice.
Related Topics
Concepts
Autonomic nervous system
Heart rate variability
Turnover
Heart rate
Internal medicine
Medicine
Sympathetic nervous system
Endocrinology
Central nervous system
Physical exercise
Parasympathetic nervous system
Cardiology
Blood pressure
Economics
Management
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3389/fphys.2018.00841
- OA Status
- gold
- Cited By
- 27
- References
- 91
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2808679697
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2808679697Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fphys.2018.00841Digital Object Identifier
- Title
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Changes in Heart Rate and Its Regulation by the Autonomic Nervous System Do Not Differ Between Forced and Voluntary Exercise in MiceWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-07-16Full publication date if available
- Authors
-
Robert Lakin, Camilo Guzmán, Farzad Izaddoustdar, Nazari Polidovitch, Jack M. Goodman, Peter H. BackxList of authors in order
- Landing page
-
https://doi.org/10.3389/fphys.2018.00841Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.3389/fphys.2018.00841Direct OA link when available
- Concepts
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Autonomic nervous system, Heart rate variability, Turnover, Heart rate, Internal medicine, Medicine, Sympathetic nervous system, Endocrinology, Central nervous system, Physical exercise, Parasympathetic nervous system, Cardiology, Blood pressure, Economics, ManagementTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
27Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4, 2024: 6, 2023: 3, 2022: 1, 2021: 7Per-year citation counts (last 5 years)
- References (count)
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91Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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