Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk Article Swipe
Aida Moreno‐Moral
,
Marta Bagnati
,
Surya Koturan
,
Jeong‐Hun Ko
,
Carmen Fonseca
,
Nathan Harmston
,
Laurence Gamé
,
Javier Martı́n
,
Voon H Ong
,
David Abraham
,
Christopher P. Denton
,
Jacques Behmoaras
,
Enrico Petretto
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1136/annrheumdis-2017-212454
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1136/annrheumdis-2017-212454
Our data further establish the link between macrophages and SSc, and suggest that the contribution of the rs3894194 risk variant to SSc susceptibility can be mediated by GSDMA expression in macrophages.
Related Topics
Concepts
Expression quantitative trait loci
Transcriptome
Downregulation and upregulation
Immunology
Innate immune system
Genome-wide association study
Immune system
Biology
Gene expression profiling
Gene expression
Gene
Genetics
Medicine
Single-nucleotide polymorphism
Genotype
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/annrheumdis-2017-212454
- https://ard.bmj.com/content/annrheumdis/77/4/596.full.pdf
- OA Status
- hybrid
- Cited By
- 77
- References
- 37
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2783530444
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2783530444Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/annrheumdis-2017-212454Digital Object Identifier
- Title
-
Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease riskWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-01-18Full publication date if available
- Authors
-
Aida Moreno‐Moral, Marta Bagnati, Surya Koturan, Jeong‐Hun Ko, Carmen Fonseca, Nathan Harmston, Laurence Gamé, Javier Martı́n, Voon H Ong, David Abraham, Christopher P. Denton, Jacques Behmoaras, Enrico PetrettoList of authors in order
- Landing page
-
https://doi.org/10.1136/annrheumdis-2017-212454Publisher landing page
- PDF URL
-
https://ard.bmj.com/content/annrheumdis/77/4/596.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://ard.bmj.com/content/annrheumdis/77/4/596.full.pdfDirect OA link when available
- Concepts
-
Expression quantitative trait loci, Transcriptome, Downregulation and upregulation, Immunology, Innate immune system, Genome-wide association study, Immune system, Biology, Gene expression profiling, Gene expression, Gene, Genetics, Medicine, Single-nucleotide polymorphism, GenotypeTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
77Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 6, 2024: 12, 2023: 9, 2022: 15, 2021: 14Per-year citation counts (last 5 years)
- References (count)
-
37Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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