Changes in metabolite profiles and antioxidant and hypoglycemic activities of Laminaria japonica after fermentation Article Swipe
Qiulin Yue
,
Zhongjian Wang
,
Fupeng Yu
,
Xueyang Tang
,
Le Su
,
Song Zhang
,
Xin Sun
,
Kunlun Li
,
Chen Zhao
,
Lin Zhao
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.lwt.2022.113122
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.lwt.2022.113122
The seaweed Laminaria japonica is considered as a potentially sustainable marine resource with good nutritional and medicinal value. Saccharomyces cerevisiae and two Lactiplantibacillus strains were added to the starter culture of mixed fermentation of L. japonica. The effects of fermentation on the metabolite profiles and antioxidant and hypoglycemic activities of fermented L. japonica were evaluated. Untargeted metabolomics analysis showed that levels of organic acids, phenolics, vitamins, and unsaturated fatty acids were significantly increased, whereas those of carbohydrates and saturated fatty acids were decreased in fermented samples. Kyoto Encyclopedia of Genes and Genomes analysis indicated that microbial metabolism, amino acid metabolism, and vitamin metabolism were involved in fermentation. In vitro spectrophotometric assays demonstrated that the scavenging activities of ABTS radicals, reducing power, and α-amylase and α-glucosidase inhibitory activities of L. japonica were remarkably enhanced by fermentation. Furthermore, fermented L. japonica showed hypoglycemic effects on insulin-resistant HepG2 cells. Our study provides an effective strategy of step fermentation by S. cerevisiae and Lactiplantibacillus for improving the phytochemical components and bioactivities of seaweeds.
Related Topics
Concepts
Fermentation
Japonica
Food science
Antioxidant
Metabolite
Phytochemical
ABTS
Chemistry
Lactic acid fermentation
Biochemistry
Biology
Lactic acid
Botany
Bacteria
DPPH
Genetics
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.lwt.2022.113122
- OA Status
- gold
- Cited By
- 33
- References
- 57
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4205591237
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4205591237Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.lwt.2022.113122Digital Object Identifier
- Title
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Changes in metabolite profiles and antioxidant and hypoglycemic activities of Laminaria japonica after fermentationWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-01-19Full publication date if available
- Authors
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Qiulin Yue, Zhongjian Wang, Fupeng Yu, Xueyang Tang, Le Su, Song Zhang, Xin Sun, Kunlun Li, Chen Zhao, Lin ZhaoList of authors in order
- Landing page
-
https://doi.org/10.1016/j.lwt.2022.113122Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1016/j.lwt.2022.113122Direct OA link when available
- Concepts
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Fermentation, Japonica, Food science, Antioxidant, Metabolite, Phytochemical, ABTS, Chemistry, Lactic acid fermentation, Biochemistry, Biology, Lactic acid, Botany, Bacteria, DPPH, GeneticsTop concepts (fields/topics) attached by OpenAlex
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33Total citation count in OpenAlex
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2025: 9, 2024: 12, 2023: 9, 2022: 3Per-year citation counts (last 5 years)
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57Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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