Changes in Oral and Salivary Contents in Patients with Chronic Kidney Disease Article Swipe
Bakhtawar Farooq
,
Abida Jaffar
,
Zahid Habib Qureshi
,
Nabeela Yasmeen
,
Rushda Rehman
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.37185/lns.1.1.514
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.37185/lns.1.1.514
Objective: To analyze oral manifestations and changes in salivary contents in patients with chronic kidney disease (CKD).Study Design: A comparative study.Place and Duration of Study: This study was conducted at the Nephrology Department of Ibne-Sina Hospital Multan, Pakistan from January 2021 to the Nephrology January 2023.Methods: Patients diagnosed with chronic kidney disease were included in the study after giving informed consent. The study was conducted on 100 subjects: 50 were chronic kidney disease (patients (study group), and 50 were period on tally and systematically healthy participants (control group). Saliva samples of all participants were collected and sent to a laboratory for detailed analysis.Results: The chronic kidney disease (CKD) patients had significantly reduced salivary flow compared to the healthy controls (P<0.001). The major oral manifestation in the study group was the the study group was the paleness of mucosa followed by calculus formation and bleeding of gums. The salivary sodium level in healthy controls was 13.4 ± 8.6, while in dialysis patients, it was 34.1 ± 19.3; this difference was statistically significant (P<0.001). Potassium level in control group was 19.2 ± 3.8 and in the study group was 22.5 ± 3.1 (P<0.001). The calcium level in the control group was 6.6 ± 2.1, and in the study group was 4.32 ± 4.55 (P<0.001). The Phosphorus level in control group was 5.5 ± 3.8 and study in study group was 27 ± 4.45 (P<0.001).Conclusion: Salivary calcium, phosphorus, urea, sodium, and potassium levels in chronic kidney disease are significantly higher than those in normal individuals. These increased levels are correlated with the severity of renal disease. Decreased salivary flow rate and calculus deposition reflect increased salivary urea and renal disorder. How to cite this: Farooq B, Jaffar A, Qureshi ZH, Yasmeen N, Rehman R. Changes in Oral and Salivary Contents in Patients with Chronic Kidney Disease. Life and Science.2025; 6(1): 145-149. doi: http://doi.org/10.37185/LnS.1.1.514
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Metadata
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4408858751Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.37185/lns.1.1.514Digital Object Identifier
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Changes in Oral and Salivary Contents in Patients with Chronic Kidney DiseaseWork title
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articleOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-01-10Full publication date if available
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Bakhtawar Farooq, Abida Jaffar, Zahid Habib Qureshi, Nabeela Yasmeen, Rushda RehmanList of authors in order
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https://doi.org/10.37185/lns.1.1.514Publisher landing page
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.37185/lns.1.1.514Direct OA link when available
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Kidney disease, Medicine, Gastroenterology, Internal medicine, Dentistry, DermatologyTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.(P<0.001). | 119, 171, 190, 211 |
| abstract_inverted_index.2023.Methods: | 45 |
| abstract_inverted_index.Science.2025; | 305 |
| abstract_inverted_index.manifestation | 123 |
| abstract_inverted_index.significantly | 110, 245 |
| abstract_inverted_index.statistically | 169 |
| abstract_inverted_index.manifestations | 4 |
| abstract_inverted_index.systematically | 83 |
| abstract_inverted_index.analysis.Results: | 102 |
| abstract_inverted_index.(P<0.001).Conclusion: | 231 |
| abstract_inverted_index.http://doi.org/10.37185/LnS.1.1.514 | 309 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 5 |
| citation_normalized_percentile.value | 0.11895003 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |