Channeling of Brain Towards Engaging Sensorimotor Tasks for Inducing Hedonic Pleasure to Alleviate Blood Pressure in Hypertension Article Swipe
YOU?
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· 2022
· Open Access
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· DOI: https://doi.org/10.1177/09727531221135999
Background: Hypertension is a modifiable risk factor for cardiovascular disease and is responsible for major deaths due to stroke and coronary heart disease. Several pharmacological and non-pharmacological interventions for reducing blood pressure have been tried earlier. Modulating brain regions such as prefrontal cortex (PFC) to channelize activities is an effective tool to target blood pressure. Purpose: Prefrontal cortex (PFC) exerts inhibitory control over sympathoexcitatory circuits, which was explored using a novel reaction time paradigm. Methods: Thirty participants of both genders in the age group 40–70 years with established hypertension were included. A structured reaction time paradigm was designed to include psychomotor and visuomotor elements with integrated sensory attention and motor performance tasks. Blood pressure, Lead II ECG, and EEG from F3 and F4 were recorded. A paired t-test was used to examine the variations in these parameters across tasks. Results: A significant reduction in mean arterial pressure by 4.04 mmHg ( p = .0232) during the visuomotor task and a reduction of 3.38 mmHg during the auditory cue task ( p = .0446) were observed. Analysis of the difference in heart rate has shown a profound decrease after passive listening tasks by 3.7 beats ( p < .0001*). Spectral analysis from F3 and F4 shows high power in low-frequency zone of EEG indicating a relaxed state during auditory cues and passive listening. Conclusion: The reaction time paradigm, when applied to hypertensives, helped decrease blood pressure and heart rate and improved the high frequency (HF) component of heart rate variability, indicating parasympathetic dominance. Such reward-oriented paradigms may act as biofeedback modules that cause hyperactivity of the PFC to suppress the sympathoexcitatory circuit with increased parasympathetic activity beneficial to hypertensive individuals.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1177/09727531221135999
- OA Status
- diamond
- Cited By
- 2
- References
- 52
- Related Works
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- OpenAlex ID
- https://openalex.org/W4312127330
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4312127330Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1177/09727531221135999Digital Object Identifier
- Title
-
Channeling of Brain Towards Engaging Sensorimotor Tasks for Inducing Hedonic Pleasure to Alleviate Blood Pressure in HypertensionWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-12-12Full publication date if available
- Authors
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Madhuri Taranikanti, Aswin Kumar Mudunuru, Archana Gaur, Anzala Kauser, Sai Shriya Taranikanti, Madhusudhan Umesh, Vidya Ganji, Kalpana Medala, Roja Katta, Varatharajan Sakthivadivel, Akhila Dronamraju, Rohith Kumar GuntukaList of authors in order
- Landing page
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https://doi.org/10.1177/09727531221135999Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1177/09727531221135999Direct OA link when available
- Concepts
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Blood pressure, Medicine, Heart rate, Heart rate variability, Electroencephalography, Psychomotor vigilance task, Sensory system, Dorsolateral prefrontal cortex, Audiology, Cardiology, Prefrontal cortex, Cognition, Neuroscience, Psychology, Internal medicine, Psychiatry, Sleep deprivationTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2025: 1, 2024: 1Per-year citation counts (last 5 years)
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52Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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