Characterization of Humulus lupulus glycosides with porous graphitic carbon and sequential high performance liquid chromatography quadrupole time-of-flight mass spectrometry and high performance liquid chromatography fractionation Article Swipe
Andrew Caffrey
,
Scott Lafontaine
,
Jeff Dailey
,
Scott Varnum
,
Larry Lerno
,
Jerry Zweigenbaum
,
Hildegarde Heymann
,
Susan E. Ebeler
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.chroma.2022.463130
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.1016/j.chroma.2022.463130
Monoterpenes contribute to the characteristic aroma of several hop varieties and may occur as nonvolatile glycosides. Upon hydrolysis, the volatile terpenes are released from the glycoside precursors. Little is known, however, about the glycoside composition of hops. Seven pentose-hexose monoterpene alcohol glycosides from dried Humulus lupulus L. cv. Citra cones were isolated using high performance liquid chromatography separation and fractionation on a reverse phase phenyl-hexyl column. Further evaluation of each isolated fraction through HPLC qTOF MS with porous graphitic carbon (PGC) showed that the seven isolated monoterpenyl glycoside fractions could be further resolved into 20 isomers. Isolation on phenyl-hexyl followed by separation on PGC was needed to distinguish each isomer present. Additionally, the hop cones were screened for potential aroma glycosides. Using the PGC column combined with a database of over 900 potential glycosides, the identification of 21 additional monoterpene-polyol, norisoprenoid, volatile phenol, and aliphatic alcohol glycosides is reported.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.chroma.2022.463130
- OA Status
- hybrid
- Cited By
- 13
- References
- 34
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4229335276
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4229335276Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.chroma.2022.463130Digital Object Identifier
- Title
-
Characterization of Humulus lupulus glycosides with porous graphitic carbon and sequential high performance liquid chromatography quadrupole time-of-flight mass spectrometry and high performance liquid chromatography fractionationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-05-08Full publication date if available
- Authors
-
Andrew Caffrey, Scott Lafontaine, Jeff Dailey, Scott Varnum, Larry Lerno, Jerry Zweigenbaum, Hildegarde Heymann, Susan E. EbelerList of authors in order
- Landing page
-
https://doi.org/10.1016/j.chroma.2022.463130Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1016/j.chroma.2022.463130Direct OA link when available
- Concepts
-
Chemistry, Glycoside, Chromatography, Humulus lupulus, High-performance liquid chromatography, Monoterpene, Mass spectrometry, Aroma, Organic chemistry, Food science, PepperTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
13Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 3, 2024: 2, 2023: 7, 2022: 1Per-year citation counts (last 5 years)
- References (count)
-
34Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4229335276 |
|---|---|
| doi | https://doi.org/10.1016/j.chroma.2022.463130 |
| ids.doi | https://doi.org/10.1016/j.chroma.2022.463130 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/35605468 |
| ids.openalex | https://openalex.org/W4229335276 |
| fwci | 3.02837939 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D002244 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Carbon |
| mesh[1].qualifier_ui | Q000379 |
| mesh[1].descriptor_ui | D002851 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | methods |
| mesh[1].descriptor_name | Chromatography, High Pressure Liquid |
| mesh[2].qualifier_ui | Q000032 |
| mesh[2].descriptor_ui | D006027 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | analysis |
| mesh[2].descriptor_name | Glycosides |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D006108 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Graphite |
| mesh[4].qualifier_ui | Q000737 |
| mesh[4].descriptor_ui | D027582 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | chemistry |
| mesh[4].descriptor_name | Humulus |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D013058 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Mass Spectrometry |
| mesh[6].qualifier_ui | Q000032 |
| mesh[6].descriptor_ui | D039821 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | analysis |
| mesh[6].descriptor_name | Monoterpenes |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D016062 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Porosity |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D002244 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Carbon |
| mesh[9].qualifier_ui | Q000379 |
| mesh[9].descriptor_ui | D002851 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | methods |
| mesh[9].descriptor_name | Chromatography, High Pressure Liquid |
| mesh[10].qualifier_ui | Q000032 |
| mesh[10].descriptor_ui | D006027 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | analysis |
| mesh[10].descriptor_name | Glycosides |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D006108 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Graphite |
| mesh[12].qualifier_ui | Q000737 |
| mesh[12].descriptor_ui | D027582 |
| mesh[12].is_major_topic | True |
| mesh[12].qualifier_name | chemistry |
| mesh[12].descriptor_name | Humulus |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D013058 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Mass Spectrometry |
| mesh[14].qualifier_ui | Q000032 |
| mesh[14].descriptor_ui | D039821 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | analysis |
| mesh[14].descriptor_name | Monoterpenes |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D016062 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Porosity |
| type | article |
| title | Characterization of Humulus lupulus glycosides with porous graphitic carbon and sequential high performance liquid chromatography quadrupole time-of-flight mass spectrometry and high performance liquid chromatography fractionation |
| biblio.issue | |
| biblio.volume | 1674 |
| biblio.last_page | 463130 |
| biblio.first_page | 463130 |
| grants[0].funder | https://openalex.org/F4320310826 |
| grants[0].award_id | |
| grants[0].funder_display_name | American Vineyard Foundation |
| topics[0].id | https://openalex.org/T13798 |
| topics[0].field.id | https://openalex.org/fields/30 |
| topics[0].field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| topics[0].score | 0.9998000264167786 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/3004 |
| topics[0].subfield.display_name | Pharmacology |
| topics[0].display_name | Hops Chemistry and Applications |
| topics[1].id | https://openalex.org/T10750 |
| topics[1].field.id | https://openalex.org/fields/11 |
| topics[1].field.display_name | Agricultural and Biological Sciences |
| topics[1].score | 0.9997000098228455 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1106 |
| topics[1].subfield.display_name | Food Science |
| topics[1].display_name | Fermentation and Sensory Analysis |
| topics[2].id | https://openalex.org/T10035 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9983999729156494 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2704 |
| topics[2].subfield.display_name | Biochemistry |
| topics[2].display_name | Phytochemicals and Antioxidant Activities |
| funders[0].id | https://openalex.org/F4320310826 |
| funders[0].ror | https://ror.org/008ebwt42 |
| funders[0].display_name | American Vineyard Foundation |
| is_xpac | False |
| apc_list.value | 3490 |
| apc_list.currency | USD |
| apc_list.value_usd | 3490 |
| apc_paid.value | 3490 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 3490 |
| concepts[0].id | https://openalex.org/C185592680 |
| concepts[0].level | 0 |
| concepts[0].score | 0.918707013130188 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q2329 |
| concepts[0].display_name | Chemistry |
| concepts[1].id | https://openalex.org/C194671627 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7980567216873169 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q192639 |
| concepts[1].display_name | Glycoside |
| concepts[2].id | https://openalex.org/C43617362 |
| concepts[2].level | 1 |
| concepts[2].score | 0.7810275554656982 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q170050 |
| concepts[2].display_name | Chromatography |
| concepts[3].id | https://openalex.org/C2779421835 |
| concepts[3].level | 3 |
| concepts[3].score | 0.7456048130989075 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q104212 |
| concepts[3].display_name | Humulus lupulus |
| concepts[4].id | https://openalex.org/C179998833 |
| concepts[4].level | 2 |
| concepts[4].score | 0.5001683235168457 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q381233 |
| concepts[4].display_name | High-performance liquid chromatography |
| concepts[5].id | https://openalex.org/C2777671706 |
| concepts[5].level | 2 |
| concepts[5].score | 0.48281869292259216 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q32528 |
| concepts[5].display_name | Monoterpene |
| concepts[6].id | https://openalex.org/C162356407 |
| concepts[6].level | 2 |
| concepts[6].score | 0.4739130735397339 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q180809 |
| concepts[6].display_name | Mass spectrometry |
| concepts[7].id | https://openalex.org/C2780563676 |
| concepts[7].level | 2 |
| concepts[7].score | 0.45676445960998535 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1758872 |
| concepts[7].display_name | Aroma |
| concepts[8].id | https://openalex.org/C178790620 |
| concepts[8].level | 1 |
| concepts[8].score | 0.34310460090637207 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11351 |
| concepts[8].display_name | Organic chemistry |
| concepts[9].id | https://openalex.org/C31903555 |
| concepts[9].level | 1 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q1637030 |
| concepts[9].display_name | Food science |
| concepts[10].id | https://openalex.org/C2776242653 |
| concepts[10].level | 2 |
| concepts[10].score | 0.0 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q22907699 |
| concepts[10].display_name | Pepper |
| keywords[0].id | https://openalex.org/keywords/chemistry |
| keywords[0].score | 0.918707013130188 |
| keywords[0].display_name | Chemistry |
| keywords[1].id | https://openalex.org/keywords/glycoside |
| keywords[1].score | 0.7980567216873169 |
| keywords[1].display_name | Glycoside |
| keywords[2].id | https://openalex.org/keywords/chromatography |
| keywords[2].score | 0.7810275554656982 |
| keywords[2].display_name | Chromatography |
| keywords[3].id | https://openalex.org/keywords/humulus-lupulus |
| keywords[3].score | 0.7456048130989075 |
| keywords[3].display_name | Humulus lupulus |
| keywords[4].id | https://openalex.org/keywords/high-performance-liquid-chromatography |
| keywords[4].score | 0.5001683235168457 |
| keywords[4].display_name | High-performance liquid chromatography |
| keywords[5].id | https://openalex.org/keywords/monoterpene |
| keywords[5].score | 0.48281869292259216 |
| keywords[5].display_name | Monoterpene |
| keywords[6].id | https://openalex.org/keywords/mass-spectrometry |
| keywords[6].score | 0.4739130735397339 |
| keywords[6].display_name | Mass spectrometry |
| keywords[7].id | https://openalex.org/keywords/aroma |
| keywords[7].score | 0.45676445960998535 |
| keywords[7].display_name | Aroma |
| keywords[8].id | https://openalex.org/keywords/organic-chemistry |
| keywords[8].score | 0.34310460090637207 |
| keywords[8].display_name | Organic chemistry |
| language | en |
| locations[0].id | doi:10.1016/j.chroma.2022.463130 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S176136234 |
| locations[0].source.issn | 0021-9673, 1873-3778 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0021-9673 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Journal of Chromatography A |
| locations[0].source.host_organization | https://openalex.org/P4310320990 |
| locations[0].source.host_organization_name | Elsevier BV |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320990 |
| locations[0].license | cc-by-nc-nd |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by-nc-nd |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Chromatography A |
| locations[0].landing_page_url | https://doi.org/10.1016/j.chroma.2022.463130 |
| locations[1].id | pmid:35605468 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of chromatography. A |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/35605468 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5041882583 |
| authorships[0].author.orcid | |
| authorships[0].author.display_name | Andrew Caffrey |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I84218800 |
| authorships[0].affiliations[0].raw_affiliation_string | Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I84218800 |
| authorships[0].affiliations[1].raw_affiliation_string | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[0].institutions[0].id | https://openalex.org/I84218800 |
| authorships[0].institutions[0].ror | https://ror.org/05rrcem69 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I84218800 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | University of California, Davis |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Andrew J. Caffrey |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States, Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| authorships[1].author.id | https://openalex.org/A5050243310 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-4098-7711 |
| authorships[1].author.display_name | Scott Lafontaine |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I84218800 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[1].institutions[0].id | https://openalex.org/I84218800 |
| authorships[1].institutions[0].ror | https://ror.org/05rrcem69 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I84218800 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | University of California, Davis |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Scott Lafontaine |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[2].author.id | https://openalex.org/A5073789424 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Jeff Dailey |
| authorships[2].affiliations[0].raw_affiliation_string | John I. Haas, Inc., HAAS® Innovations Center, 1600 River Road, Yakima, WA, 98902, United States |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jeff Dailey |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | John I. Haas, Inc., HAAS® Innovations Center, 1600 River Road, Yakima, WA, 98902, United States |
| authorships[3].author.id | https://openalex.org/A5052214124 |
| authorships[3].author.orcid | |
| authorships[3].author.display_name | Scott Varnum |
| authorships[3].affiliations[0].raw_affiliation_string | John I. Haas, Inc., HAAS® Innovations Center, 1600 River Road, Yakima, WA, 98902, United States |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Scott Varnum |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | John I. Haas, Inc., HAAS® Innovations Center, 1600 River Road, Yakima, WA, 98902, United States |
| authorships[4].author.id | https://openalex.org/A5006434522 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-5292-3358 |
| authorships[4].author.display_name | Larry Lerno |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I84218800 |
| authorships[4].affiliations[0].raw_affiliation_string | Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I84218800 |
| authorships[4].affiliations[1].raw_affiliation_string | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[4].institutions[0].id | https://openalex.org/I84218800 |
| authorships[4].institutions[0].ror | https://ror.org/05rrcem69 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I84218800 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | University of California, Davis |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Larry A. Lerno |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States, Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| authorships[5].author.id | https://openalex.org/A5017289553 |
| authorships[5].author.orcid | https://orcid.org/0000-0003-3844-737X |
| authorships[5].author.display_name | Jerry Zweigenbaum |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I138285227 |
| authorships[5].affiliations[0].raw_affiliation_string | Agilent Technologies, Inc. Wilmington, Delaware, 19808, United States |
| authorships[5].institutions[0].id | https://openalex.org/I138285227 |
| authorships[5].institutions[0].ror | https://ror.org/02tryst02 |
| authorships[5].institutions[0].type | company |
| authorships[5].institutions[0].lineage | https://openalex.org/I138285227 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Agilent Technologies (United States) |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Jerry Zweigenbaum |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Agilent Technologies, Inc. Wilmington, Delaware, 19808, United States |
| authorships[6].author.id | https://openalex.org/A5070755746 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-9806-1842 |
| authorships[6].author.display_name | Hildegarde Heymann |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I84218800 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[6].institutions[0].id | https://openalex.org/I84218800 |
| authorships[6].institutions[0].ror | https://ror.org/05rrcem69 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I84218800 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | University of California, Davis |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Hildegarde Heymann |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[7].author.id | https://openalex.org/A5049256544 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-8394-6736 |
| authorships[7].author.display_name | Susan E. Ebeler |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I84218800 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I84218800 |
| authorships[7].affiliations[1].raw_affiliation_string | Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| authorships[7].institutions[0].id | https://openalex.org/I84218800 |
| authorships[7].institutions[0].ror | https://ror.org/05rrcem69 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I84218800 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | University of California, Davis |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Susan E. Ebeler |
| authorships[7].is_corresponding | True |
| authorships[7].raw_affiliation_strings | Department of Viticulture and Enology, University of California, Davis CA, 95616, United States, Food Safety and Measurement Facility, University of California, Davis CA, 95616, United States |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1016/j.chroma.2022.463130 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Characterization of Humulus lupulus glycosides with porous graphitic carbon and sequential high performance liquid chromatography quadrupole time-of-flight mass spectrometry and high performance liquid chromatography fractionation |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T13798 |
| primary_topic.field.id | https://openalex.org/fields/30 |
| primary_topic.field.display_name | Pharmacology, Toxicology and Pharmaceutics |
| primary_topic.score | 0.9998000264167786 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/3004 |
| primary_topic.subfield.display_name | Pharmacology |
| primary_topic.display_name | Hops Chemistry and Applications |
| related_works | https://openalex.org/W3170959991, https://openalex.org/W3158705033, https://openalex.org/W2607374816, https://openalex.org/W2994697768, https://openalex.org/W2073700361, https://openalex.org/W2140581096, https://openalex.org/W4312528904, https://openalex.org/W1133705797, https://openalex.org/W2033880222, https://openalex.org/W2767712705 |
| cited_by_count | 13 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 3 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 7 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 1 |
| locations_count | 2 |
| best_oa_location.id | doi:10.1016/j.chroma.2022.463130 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S176136234 |
| best_oa_location.source.issn | 0021-9673, 1873-3778 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 0021-9673 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Journal of Chromatography A |
| best_oa_location.source.host_organization | https://openalex.org/P4310320990 |
| best_oa_location.source.host_organization_name | Elsevier BV |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| best_oa_location.license | cc-by-nc-nd |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Chromatography A |
| best_oa_location.landing_page_url | https://doi.org/10.1016/j.chroma.2022.463130 |
| primary_location.id | doi:10.1016/j.chroma.2022.463130 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S176136234 |
| primary_location.source.issn | 0021-9673, 1873-3778 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0021-9673 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Journal of Chromatography A |
| primary_location.source.host_organization | https://openalex.org/P4310320990 |
| primary_location.source.host_organization_name | Elsevier BV |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320990 |
| primary_location.license | cc-by-nc-nd |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc-nd |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Chromatography A |
| primary_location.landing_page_url | https://doi.org/10.1016/j.chroma.2022.463130 |
| publication_date | 2022-05-08 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W2603055677, https://openalex.org/W1965804170, https://openalex.org/W6742433950, https://openalex.org/W6686453430, https://openalex.org/W1515191881, https://openalex.org/W1969078101, https://openalex.org/W2078617228, https://openalex.org/W14805379, https://openalex.org/W4316656804, https://openalex.org/W213901614, https://openalex.org/W2042318540, https://openalex.org/W3012390383, https://openalex.org/W3009977447, https://openalex.org/W2948004832, https://openalex.org/W1154569583, https://openalex.org/W2808262678, https://openalex.org/W2045100706, https://openalex.org/W1539109754, https://openalex.org/W2908810103, https://openalex.org/W6754887319, https://openalex.org/W2020087991, https://openalex.org/W2105735042, https://openalex.org/W3136523831, https://openalex.org/W2310468153, https://openalex.org/W4245927555, https://openalex.org/W2007484902, https://openalex.org/W2346006950, https://openalex.org/W6677828285, https://openalex.org/W2025279714, https://openalex.org/W3158344218, https://openalex.org/W2118667340, https://openalex.org/W2894776553, https://openalex.org/W2183538578, https://openalex.org/W2742560924 |
| referenced_works_count | 34 |
| abstract_inverted_index.a | 61, 127 |
| abstract_inverted_index.20 | 94 |
| abstract_inverted_index.21 | 137 |
| abstract_inverted_index.L. | 46 |
| abstract_inverted_index.MS | 75 |
| abstract_inverted_index.as | 13 |
| abstract_inverted_index.be | 90 |
| abstract_inverted_index.by | 100 |
| abstract_inverted_index.is | 28, 147 |
| abstract_inverted_index.of | 6, 35, 68, 129, 136 |
| abstract_inverted_index.on | 60, 97, 102 |
| abstract_inverted_index.to | 2, 106 |
| abstract_inverted_index.900 | 131 |
| abstract_inverted_index.PGC | 103, 123 |
| abstract_inverted_index.and | 10, 58, 143 |
| abstract_inverted_index.are | 21 |
| abstract_inverted_index.cv. | 47 |
| abstract_inverted_index.for | 117 |
| abstract_inverted_index.hop | 8, 113 |
| abstract_inverted_index.may | 11 |
| abstract_inverted_index.the | 3, 18, 24, 32, 83, 112, 122, 134 |
| abstract_inverted_index.was | 104 |
| abstract_inverted_index.HPLC | 73 |
| abstract_inverted_index.Upon | 16 |
| abstract_inverted_index.each | 69, 108 |
| abstract_inverted_index.from | 23, 42 |
| abstract_inverted_index.high | 53 |
| abstract_inverted_index.into | 93 |
| abstract_inverted_index.over | 130 |
| abstract_inverted_index.qTOF | 74 |
| abstract_inverted_index.that | 82 |
| abstract_inverted_index.were | 50, 115 |
| abstract_inverted_index.with | 76, 126 |
| abstract_inverted_index.(PGC) | 80 |
| abstract_inverted_index.Citra | 48 |
| abstract_inverted_index.Seven | 37 |
| abstract_inverted_index.Using | 121 |
| abstract_inverted_index.about | 31 |
| abstract_inverted_index.aroma | 5, 119 |
| abstract_inverted_index.cones | 49, 114 |
| abstract_inverted_index.could | 89 |
| abstract_inverted_index.dried | 43 |
| abstract_inverted_index.hops. | 36 |
| abstract_inverted_index.occur | 12 |
| abstract_inverted_index.phase | 63 |
| abstract_inverted_index.seven | 84 |
| abstract_inverted_index.using | 52 |
| abstract_inverted_index.Little | 27 |
| abstract_inverted_index.carbon | 79 |
| abstract_inverted_index.column | 124 |
| abstract_inverted_index.isomer | 109 |
| abstract_inverted_index.known, | 29 |
| abstract_inverted_index.liquid | 55 |
| abstract_inverted_index.needed | 105 |
| abstract_inverted_index.porous | 77 |
| abstract_inverted_index.showed | 81 |
| abstract_inverted_index.Further | 66 |
| abstract_inverted_index.Humulus | 44 |
| abstract_inverted_index.alcohol | 40, 145 |
| abstract_inverted_index.column. | 65 |
| abstract_inverted_index.further | 91 |
| abstract_inverted_index.lupulus | 45 |
| abstract_inverted_index.phenol, | 142 |
| abstract_inverted_index.reverse | 62 |
| abstract_inverted_index.several | 7 |
| abstract_inverted_index.through | 72 |
| abstract_inverted_index.combined | 125 |
| abstract_inverted_index.database | 128 |
| abstract_inverted_index.followed | 99 |
| abstract_inverted_index.fraction | 71 |
| abstract_inverted_index.however, | 30 |
| abstract_inverted_index.isolated | 51, 70, 85 |
| abstract_inverted_index.isomers. | 95 |
| abstract_inverted_index.present. | 110 |
| abstract_inverted_index.released | 22 |
| abstract_inverted_index.resolved | 92 |
| abstract_inverted_index.screened | 116 |
| abstract_inverted_index.terpenes | 20 |
| abstract_inverted_index.volatile | 19, 141 |
| abstract_inverted_index.Isolation | 96 |
| abstract_inverted_index.aliphatic | 144 |
| abstract_inverted_index.fractions | 88 |
| abstract_inverted_index.glycoside | 25, 33, 87 |
| abstract_inverted_index.graphitic | 78 |
| abstract_inverted_index.potential | 118, 132 |
| abstract_inverted_index.reported. | 148 |
| abstract_inverted_index.varieties | 9 |
| abstract_inverted_index.additional | 138 |
| abstract_inverted_index.contribute | 1 |
| abstract_inverted_index.evaluation | 67 |
| abstract_inverted_index.glycosides | 41, 146 |
| abstract_inverted_index.separation | 57, 101 |
| abstract_inverted_index.composition | 34 |
| abstract_inverted_index.distinguish | 107 |
| abstract_inverted_index.glycosides, | 133 |
| abstract_inverted_index.glycosides. | 15, 120 |
| abstract_inverted_index.hydrolysis, | 17 |
| abstract_inverted_index.monoterpene | 39 |
| abstract_inverted_index.nonvolatile | 14 |
| abstract_inverted_index.performance | 54 |
| abstract_inverted_index.precursors. | 26 |
| abstract_inverted_index.Monoterpenes | 0 |
| abstract_inverted_index.monoterpenyl | 86 |
| abstract_inverted_index.phenyl-hexyl | 64, 98 |
| abstract_inverted_index.Additionally, | 111 |
| abstract_inverted_index.fractionation | 59 |
| abstract_inverted_index.characteristic | 4 |
| abstract_inverted_index.chromatography | 56 |
| abstract_inverted_index.identification | 135 |
| abstract_inverted_index.norisoprenoid, | 140 |
| abstract_inverted_index.pentose-hexose | 38 |
| abstract_inverted_index.monoterpene-polyol, | 139 |
| cited_by_percentile_year.max | 99 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5049256544 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 8 |
| corresponding_institution_ids | https://openalex.org/I84218800 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/6 |
| sustainable_development_goals[0].score | 0.6000000238418579 |
| sustainable_development_goals[0].display_name | Clean water and sanitation |
| citation_normalized_percentile.value | 0.87213897 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |