CHEMICAL CONSTITUENTS FROM THE LEAVES OF Eriodictyon californicum (Hook. & Arn.) Torr. (Boraginaceae) Article Swipe
Bruno Sousa
,
Teresa Gonçalves
,
Lívia Macedo Dutra
,
Victória Laysna dos Anjos Santos
,
Emmanoel Vilaça Costa
,
Agnaldo Rodrigues de Melo Chaves
,
J. M. Pinto
,
Marcelo Silva
,
Yuri Mangueira do Nascimento
,
Josean Fechine Tavares
,
Marcelo Sobral da Silva
,
Jackson Roberto Guedes da Silva Almeida
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.21577/0100-4042.20250140
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.21577/0100-4042.20250140
Eriodictyon californicum is a species belonging to Boraginaceae family, popularly known as “yerba santa” and used in folk medicine to treat rheumatism, headaches, inflammation, and respiratory complications. In the present work, we performed phytochemical analyses of extracts from the leaves of E. californicum in order to isolate its chemical constituents. According to thin-layer chromatography (TLC) analyses, preliminary phytochemical screening indicated the presence of anthocyanins derivatives, flavonoids, condensed and hydrolysable tannins. Furthermore, classical chromatographic techniques (column chromatography, analytical and preparative thin-layer chromatography) led to the isolation of secondary metabolites. The compounds were elucidated by 1D and 2D nuclear magnetic resonance (NMR) (correlation spectroscopy (COSY), heteronuclear single quantum correlation (HSQC) and heteronuclear multiple bond correlation (HMBC)) analysis, Fourier transform infrared (FTIR) spectroscopy, mass spectrometry (MS) analysis, and comparison with literature data. In this study, seven metabolites were identified: sterubin (1), chrysoeriol (2), apigenin (3), hydroxygenkwanin (4), 5,4’-dihydroxy-7,3’-dimethoxyflavanone (5), ethyl cinnamate (6) and 5-hydroxy7-methoxychromone (7). The compounds 1-5 were previously identified in this species, and the compounds 6 and 7 are being reported for the first time in the species E. californicum, as well as in Boraginaceae family. The 1H and 13C NMR data for some compounds have been reviewed. These results revealed that E. californicum is an important source of secondary metabolites, mainly flavonoids with chemophenetic relationships with Boraginaceae family.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.21577/0100-4042.20250140
- OA Status
- gold
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4410304218
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4410304218Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.21577/0100-4042.20250140Digital Object Identifier
- Title
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CHEMICAL CONSTITUENTS FROM THE LEAVES OF Eriodictyon californicum (Hook. & Arn.) Torr. (Boraginaceae)Work title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
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2025Year of publication
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2025-01-01Full publication date if available
- Authors
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Bruno Sousa, Teresa Gonçalves, Lívia Macedo Dutra, Victória Laysna dos Anjos Santos, Emmanoel Vilaça Costa, Agnaldo Rodrigues de Melo Chaves, J. M. Pinto, Marcelo Silva, Yuri Mangueira do Nascimento, Josean Fechine Tavares, Marcelo Sobral da Silva, Jackson Roberto Guedes da Silva AlmeidaList of authors in order
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https://doi.org/10.21577/0100-4042.20250140Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.21577/0100-4042.20250140Direct OA link when available
- Concepts
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Boraginaceae, Hook, Torr, Chemistry, Botany, Physics, Biology, Medicine, Dentistry, ThermodynamicsTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.treat | 20 |
| abstract_inverted_index.work, | 30 |
| abstract_inverted_index.(FTIR) | 118 |
| abstract_inverted_index.(HSQC) | 107 |
| abstract_inverted_index.leaves | 39 |
| abstract_inverted_index.mainly | 210 |
| abstract_inverted_index.single | 104 |
| abstract_inverted_index.source | 206 |
| abstract_inverted_index.study, | 131 |
| abstract_inverted_index.(COSY), | 102 |
| abstract_inverted_index.(HMBC)) | 113 |
| abstract_inverted_index.(column | 74 |
| abstract_inverted_index.Fourier | 115 |
| abstract_inverted_index.family, | 8 |
| abstract_inverted_index.family. | 184, 217 |
| abstract_inverted_index.isolate | 46 |
| abstract_inverted_index.nuclear | 96 |
| abstract_inverted_index.present | 29 |
| abstract_inverted_index.quantum | 105 |
| abstract_inverted_index.results | 198 |
| abstract_inverted_index.species | 4, 176 |
| abstract_inverted_index.analyses | 34 |
| abstract_inverted_index.apigenin | 140 |
| abstract_inverted_index.chemical | 48 |
| abstract_inverted_index.extracts | 36 |
| abstract_inverted_index.infrared | 117 |
| abstract_inverted_index.magnetic | 97 |
| abstract_inverted_index.medicine | 18 |
| abstract_inverted_index.multiple | 110 |
| abstract_inverted_index.presence | 61 |
| abstract_inverted_index.reported | 169 |
| abstract_inverted_index.revealed | 199 |
| abstract_inverted_index.santa” | 13 |
| abstract_inverted_index.species, | 160 |
| abstract_inverted_index.sterubin | 136 |
| abstract_inverted_index.tannins. | 69 |
| abstract_inverted_index.“yerba | 12 |
| abstract_inverted_index.According | 50 |
| abstract_inverted_index.analyses, | 55 |
| abstract_inverted_index.analysis, | 114, 123 |
| abstract_inverted_index.belonging | 5 |
| abstract_inverted_index.cinnamate | 147 |
| abstract_inverted_index.classical | 71 |
| abstract_inverted_index.compounds | 89, 153, 163, 193 |
| abstract_inverted_index.condensed | 66 |
| abstract_inverted_index.important | 205 |
| abstract_inverted_index.indicated | 59 |
| abstract_inverted_index.isolation | 84 |
| abstract_inverted_index.performed | 32 |
| abstract_inverted_index.popularly | 9 |
| abstract_inverted_index.resonance | 98 |
| abstract_inverted_index.reviewed. | 196 |
| abstract_inverted_index.screening | 58 |
| abstract_inverted_index.secondary | 86, 208 |
| abstract_inverted_index.transform | 116 |
| abstract_inverted_index.analytical | 76 |
| abstract_inverted_index.comparison | 125 |
| abstract_inverted_index.elucidated | 91 |
| abstract_inverted_index.flavonoids | 211 |
| abstract_inverted_index.headaches, | 22 |
| abstract_inverted_index.identified | 157 |
| abstract_inverted_index.literature | 127 |
| abstract_inverted_index.previously | 156 |
| abstract_inverted_index.techniques | 73 |
| abstract_inverted_index.thin-layer | 52, 79 |
| abstract_inverted_index.Eriodictyon | 0 |
| abstract_inverted_index.chrysoeriol | 138 |
| abstract_inverted_index.correlation | 106, 112 |
| abstract_inverted_index.flavonoids, | 65 |
| abstract_inverted_index.identified: | 135 |
| abstract_inverted_index.metabolites | 133 |
| abstract_inverted_index.preliminary | 56 |
| abstract_inverted_index.preparative | 78 |
| abstract_inverted_index.respiratory | 25 |
| abstract_inverted_index.rheumatism, | 21 |
| abstract_inverted_index.(correlation | 100 |
| abstract_inverted_index.Boraginaceae | 7, 183, 216 |
| abstract_inverted_index.Furthermore, | 70 |
| abstract_inverted_index.anthocyanins | 63 |
| abstract_inverted_index.californicum | 1, 42, 202 |
| abstract_inverted_index.derivatives, | 64 |
| abstract_inverted_index.hydrolysable | 68 |
| abstract_inverted_index.metabolites, | 209 |
| abstract_inverted_index.metabolites. | 87 |
| abstract_inverted_index.spectrometry | 121 |
| abstract_inverted_index.spectroscopy | 101 |
| abstract_inverted_index.californicum, | 178 |
| abstract_inverted_index.chemophenetic | 213 |
| abstract_inverted_index.constituents. | 49 |
| abstract_inverted_index.heteronuclear | 103, 109 |
| abstract_inverted_index.inflammation, | 23 |
| abstract_inverted_index.phytochemical | 33, 57 |
| abstract_inverted_index.relationships | 214 |
| abstract_inverted_index.spectroscopy, | 119 |
| abstract_inverted_index.chromatography | 53 |
| abstract_inverted_index.complications. | 26 |
| abstract_inverted_index.chromatographic | 72 |
| abstract_inverted_index.chromatography) | 80 |
| abstract_inverted_index.chromatography, | 75 |
| abstract_inverted_index.hydroxygenkwanin | 142 |
| abstract_inverted_index.5-hydroxy7-methoxychromone | 150 |
| abstract_inverted_index.5,4’-dihydroxy-7,3’-dimethoxyflavanone | 144 |
| cited_by_percentile_year | |
| countries_distinct_count | 0 |
| institutions_distinct_count | 12 |
| citation_normalized_percentile.value | 0.11859802 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |