Chemically Defined Neural Conversion of Human Pluripotent Stem Cells Article Swipe

View

Yu Chen , Carlos A. Tristan , Sunil K. Mallanna , Pinar Ormanoglu , Steven A. Titus , Anton Simeonov , Ilyas Singeç ·

YOU? · · 2019 · Open Access · · DOI: https://doi.org/10.1007/978-1-4939-9007-8_5

Related Topics

Computational Biology

Concepts

Induced pluripotent stem cell Neural stem cell Biology Neural cell Neuroscience Cell type Stem cell Computational biology Computer science Cell Cell biology Embryonic stem cell Genetics Gene

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1007/978-1-4939-9007-8_5
OA Status: green
Cited By: 1
References: 26
Related Works: 10
OpenAlex ID: https://openalex.org/W2911114395

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W2911114395

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1007/978-1-4939-9007-8_5

Digital Object Identifier
Title: Chemically Defined Neural Conversion of Human Pluripotent Stem Cells

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2019

Year of publication
Publication date: 2019-01-01

Full publication date if available
Authors: Yu Chen, Carlos A. Tristan, Sunil K. Mallanna, Pinar Ormanoglu, Steven A. Titus, Anton Simeonov, Ilyas Singeç

List of authors in order
Landing page: https://doi.org/10.1007/978-1-4939-9007-8_5

Publisher landing page
Open access: Yes

Whether a free full text is available
OA status: green

Open access status per OpenAlex
OA URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6908303

Direct OA link when available
Concepts: Induced pluripotent stem cell, Neural stem cell, Biology, Neural cell, Neuroscience, Cell type, Stem cell, Computational biology, Computer science, Cell, Cell biology, Embryonic stem cell, Genetics, Gene

Top concepts (fields/topics) attached by OpenAlex
Cited by: 1

Total citation count in OpenAlex
Citations by year (recent): 2025: 1

Per-year citation counts (last 5 years)
References (count): 26

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W2911114395
doi	https://doi.org/10.1007/978-1-4939-9007-8_5
ids.doi	https://doi.org/10.1007/978-1-4939-9007-8_5
ids.mag	2911114395
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/30656621
ids.openalex	https://openalex.org/W2911114395
fwci	0.0
mesh[0].qualifier_ui
mesh[0].descriptor_ui	D000818
mesh[0].is_major_topic	False
mesh[0].qualifier_name
mesh[0].descriptor_name	Animals
mesh[1].qualifier_ui
mesh[1].descriptor_ui	D015415
mesh[1].is_major_topic	False
mesh[1].qualifier_name
mesh[1].descriptor_name	Biomarkers
mesh[2].qualifier_ui
mesh[2].descriptor_ui	D018929
mesh[2].is_major_topic	False
mesh[2].qualifier_name
mesh[2].descriptor_name	Cell Culture Techniques
mesh[3].qualifier_ui	Q000187
mesh[3].descriptor_ui	D002454
mesh[3].is_major_topic	False
mesh[3].qualifier_name	drug effects
mesh[3].descriptor_name	Cell Differentiation
mesh[4].qualifier_ui	Q000166
mesh[4].descriptor_ui	D053595
mesh[4].is_major_topic	False
mesh[4].qualifier_name	cytology
mesh[4].descriptor_name	Embryonic Stem Cells
mesh[5].qualifier_ui	Q000187
mesh[5].descriptor_ui	D053595
mesh[5].is_major_topic	False
mesh[5].qualifier_name	drug effects
mesh[5].descriptor_name	Embryonic Stem Cells
mesh[6].qualifier_ui	Q000378
mesh[6].descriptor_ui	D053595
mesh[6].is_major_topic	False
mesh[6].qualifier_name	metabolism
mesh[6].descriptor_name	Embryonic Stem Cells
mesh[7].qualifier_ui
mesh[7].descriptor_ui	D006801
mesh[7].is_major_topic	False
mesh[7].qualifier_name
mesh[7].descriptor_name	Humans
mesh[8].qualifier_ui
mesh[8].descriptor_ui	D007150
mesh[8].is_major_topic	False
mesh[8].qualifier_name
mesh[8].descriptor_name	Immunohistochemistry
mesh[9].qualifier_ui
mesh[9].descriptor_ui	D016130
mesh[9].is_major_topic	False
mesh[9].qualifier_name
mesh[9].descriptor_name	Immunophenotyping
mesh[10].qualifier_ui	Q000166
mesh[10].descriptor_ui	D057026
mesh[10].is_major_topic	False
mesh[10].qualifier_name	cytology
mesh[10].descriptor_name	Induced Pluripotent Stem Cells
mesh[11].qualifier_ui	Q000187
mesh[11].descriptor_ui	D057026
mesh[11].is_major_topic	False
mesh[11].qualifier_name	drug effects
mesh[11].descriptor_name	Induced Pluripotent Stem Cells
mesh[12].qualifier_ui	Q000378
mesh[12].descriptor_ui	D057026
mesh[12].is_major_topic	False
mesh[12].qualifier_name	metabolism
mesh[12].descriptor_name	Induced Pluripotent Stem Cells
mesh[13].qualifier_ui
mesh[13].descriptor_ui	D051379
mesh[13].is_major_topic	False
mesh[13].qualifier_name
mesh[13].descriptor_name	Mice
mesh[14].qualifier_ui	Q000166
mesh[14].descriptor_ui	D058953
mesh[14].is_major_topic	False
mesh[14].qualifier_name	cytology
mesh[14].descriptor_name	Neural Stem Cells
mesh[15].qualifier_ui	Q000187
mesh[15].descriptor_ui	D058953
mesh[15].is_major_topic	False
mesh[15].qualifier_name	drug effects
mesh[15].descriptor_name	Neural Stem Cells
mesh[16].qualifier_ui	Q000378
mesh[16].descriptor_ui	D058953
mesh[16].is_major_topic	False
mesh[16].qualifier_name	metabolism
mesh[16].descriptor_name	Neural Stem Cells
mesh[17].qualifier_ui	Q000166
mesh[17].descriptor_ui	D039904
mesh[17].is_major_topic	False
mesh[17].qualifier_name	cytology
mesh[17].descriptor_name	Pluripotent Stem Cells
mesh[18].qualifier_ui	Q000187
mesh[18].descriptor_ui	D039904
mesh[18].is_major_topic	False
mesh[18].qualifier_name	drug effects
mesh[18].descriptor_name	Pluripotent Stem Cells
mesh[19].qualifier_ui	Q000378
mesh[19].descriptor_ui	D039904
mesh[19].is_major_topic	False
mesh[19].qualifier_name	metabolism
mesh[19].descriptor_name	Pluripotent Stem Cells
mesh[20].qualifier_ui
mesh[20].descriptor_ui	D000818
mesh[20].is_major_topic	False
mesh[20].qualifier_name
mesh[20].descriptor_name	Animals
mesh[21].qualifier_ui
mesh[21].descriptor_ui	D015415
mesh[21].is_major_topic	False
mesh[21].qualifier_name
mesh[21].descriptor_name	Biomarkers
mesh[22].qualifier_ui
mesh[22].descriptor_ui	D018929
mesh[22].is_major_topic	False
mesh[22].qualifier_name
mesh[22].descriptor_name	Cell Culture Techniques
mesh[23].qualifier_ui	Q000187
mesh[23].descriptor_ui	D002454
mesh[23].is_major_topic	False
mesh[23].qualifier_name	drug effects
mesh[23].descriptor_name	Cell Differentiation
mesh[24].qualifier_ui	Q000166
mesh[24].descriptor_ui	D053595
mesh[24].is_major_topic	False
mesh[24].qualifier_name	cytology
mesh[24].descriptor_name	Embryonic Stem Cells
mesh[25].qualifier_ui	Q000187
mesh[25].descriptor_ui	D053595
mesh[25].is_major_topic	False
mesh[25].qualifier_name	drug effects
mesh[25].descriptor_name	Embryonic Stem Cells
mesh[26].qualifier_ui	Q000378
mesh[26].descriptor_ui	D053595
mesh[26].is_major_topic	False
mesh[26].qualifier_name	metabolism
mesh[26].descriptor_name	Embryonic Stem Cells
mesh[27].qualifier_ui
mesh[27].descriptor_ui	D006801
mesh[27].is_major_topic	False
mesh[27].qualifier_name
mesh[27].descriptor_name	Humans
mesh[28].qualifier_ui
mesh[28].descriptor_ui	D007150
mesh[28].is_major_topic	False
mesh[28].qualifier_name
mesh[28].descriptor_name	Immunohistochemistry
mesh[29].qualifier_ui
mesh[29].descriptor_ui	D016130
mesh[29].is_major_topic	False
mesh[29].qualifier_name
mesh[29].descriptor_name	Immunophenotyping
mesh[30].qualifier_ui	Q000166
mesh[30].descriptor_ui	D057026
mesh[30].is_major_topic	False
mesh[30].qualifier_name	cytology
mesh[30].descriptor_name	Induced Pluripotent Stem Cells
mesh[31].qualifier_ui	Q000187
mesh[31].descriptor_ui	D057026
mesh[31].is_major_topic	False
mesh[31].qualifier_name	drug effects
mesh[31].descriptor_name	Induced Pluripotent Stem Cells
mesh[32].qualifier_ui	Q000378
mesh[32].descriptor_ui	D057026
mesh[32].is_major_topic	False
mesh[32].qualifier_name	metabolism
mesh[32].descriptor_name	Induced Pluripotent Stem Cells
mesh[33].qualifier_ui
mesh[33].descriptor_ui	D051379
mesh[33].is_major_topic	False
mesh[33].qualifier_name
mesh[33].descriptor_name	Mice
mesh[34].qualifier_ui	Q000166
mesh[34].descriptor_ui	D058953
mesh[34].is_major_topic	False
mesh[34].qualifier_name	cytology
mesh[34].descriptor_name	Neural Stem Cells
mesh[35].qualifier_ui	Q000187
mesh[35].descriptor_ui	D058953
mesh[35].is_major_topic	False
mesh[35].qualifier_name	drug effects
mesh[35].descriptor_name	Neural Stem Cells
mesh[36].qualifier_ui	Q000378
mesh[36].descriptor_ui	D058953
mesh[36].is_major_topic	False
mesh[36].qualifier_name	metabolism
mesh[36].descriptor_name	Neural Stem Cells
mesh[37].qualifier_ui	Q000166
mesh[37].descriptor_ui	D039904
mesh[37].is_major_topic	False
mesh[37].qualifier_name	cytology
mesh[37].descriptor_name	Pluripotent Stem Cells
mesh[38].qualifier_ui	Q000187
mesh[38].descriptor_ui	D039904
mesh[38].is_major_topic	False
mesh[38].qualifier_name	drug effects
mesh[38].descriptor_name	Pluripotent Stem Cells
mesh[39].qualifier_ui	Q000378
mesh[39].descriptor_ui	D039904
mesh[39].is_major_topic	False
mesh[39].qualifier_name	metabolism
mesh[39].descriptor_name	Pluripotent Stem Cells
mesh[40].qualifier_ui
mesh[40].descriptor_ui	D000818
mesh[40].is_major_topic	False
mesh[40].qualifier_name
mesh[40].descriptor_name	Animals
mesh[41].qualifier_ui
mesh[41].descriptor_ui	D015415
mesh[41].is_major_topic	False
mesh[41].qualifier_name
mesh[41].descriptor_name	Biomarkers
mesh[42].qualifier_ui
mesh[42].descriptor_ui	D018929
mesh[42].is_major_topic	False
mesh[42].qualifier_name
mesh[42].descriptor_name	Cell Culture Techniques
mesh[43].qualifier_ui	Q000187
mesh[43].descriptor_ui	D002454
mesh[43].is_major_topic	False
mesh[43].qualifier_name	drug effects
mesh[43].descriptor_name	Cell Differentiation
mesh[44].qualifier_ui	Q000166
mesh[44].descriptor_ui	D053595
mesh[44].is_major_topic	False
mesh[44].qualifier_name	cytology
mesh[44].descriptor_name	Embryonic Stem Cells
mesh[45].qualifier_ui	Q000187
mesh[45].descriptor_ui	D053595
mesh[45].is_major_topic	False
mesh[45].qualifier_name	drug effects
mesh[45].descriptor_name	Embryonic Stem Cells
mesh[46].qualifier_ui	Q000378
mesh[46].descriptor_ui	D053595
mesh[46].is_major_topic	False
mesh[46].qualifier_name	metabolism
mesh[46].descriptor_name	Embryonic Stem Cells
mesh[47].qualifier_ui
mesh[47].descriptor_ui	D006801
mesh[47].is_major_topic	False
mesh[47].qualifier_name
mesh[47].descriptor_name	Humans
mesh[48].qualifier_ui
mesh[48].descriptor_ui	D007150
mesh[48].is_major_topic	False
mesh[48].qualifier_name
mesh[48].descriptor_name	Immunohistochemistry
mesh[49].qualifier_ui
mesh[49].descriptor_ui	D016130
mesh[49].is_major_topic	False
mesh[49].qualifier_name
mesh[49].descriptor_name	Immunophenotyping
type	article
title	Chemically Defined Neural Conversion of Human Pluripotent Stem Cells
biblio.issue
biblio.volume	1919
biblio.last_page	72
biblio.first_page	59
topics[0].id	https://openalex.org/T10505
topics[0].field.id	https://openalex.org/fields/13
topics[0].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[0].score	0.9998000264167786
topics[0].domain.id	https://openalex.org/domains/1
topics[0].domain.display_name	Life Sciences
topics[0].subfield.id	https://openalex.org/subfields/1312
topics[0].subfield.display_name	Molecular Biology
topics[0].display_name	Pluripotent Stem Cells Research
topics[1].id	https://openalex.org/T11190
topics[1].field.id	https://openalex.org/fields/22
topics[1].field.display_name	Engineering
topics[1].score	0.9947999715805054
topics[1].domain.id	https://openalex.org/domains/3
topics[1].domain.display_name	Physical Sciences
topics[1].subfield.id	https://openalex.org/subfields/2204
topics[1].subfield.display_name	Biomedical Engineering
topics[1].display_name	3D Printing in Biomedical Research
topics[2].id	https://openalex.org/T11601
topics[2].field.id	https://openalex.org/fields/28
topics[2].field.display_name	Neuroscience
topics[2].score	0.9939000010490417
topics[2].domain.id	https://openalex.org/domains/1
topics[2].domain.display_name	Life Sciences
topics[2].subfield.id	https://openalex.org/subfields/2804
topics[2].subfield.display_name	Cellular and Molecular Neuroscience
topics[2].display_name	Neuroscience and Neural Engineering
funders[0].id	https://openalex.org/F4320321040
funders[0].ror	https://ror.org/02kv4zf79
funders[0].display_name	National Science Council
funders[1].id	https://openalex.org/F4320337472
funders[1].ror	https://ror.org/04pw6fb54
funders[1].display_name	National Center for Advancing Translational Sciences
funders[2].id	https://openalex.org/F4320338075
funders[2].ror	https://ror.org/00097mb19
funders[2].display_name	Core Research for Evolutional Science and Technology
is_xpac	False
apc_list
apc_paid
concepts[0].id	https://openalex.org/C107459253
concepts[0].level	4
concepts[0].score	0.7627434730529785
concepts[0].wikidata	https://www.wikidata.org/wiki/Q674925
concepts[0].display_name	Induced pluripotent stem cell
concepts[1].id	https://openalex.org/C136834591
concepts[1].level	3
concepts[1].score	0.6313843131065369
concepts[1].wikidata	https://www.wikidata.org/wiki/Q2944097
concepts[1].display_name	Neural stem cell
concepts[2].id	https://openalex.org/C86803240
concepts[2].level	0
concepts[2].score	0.5147700309753418
concepts[2].wikidata	https://www.wikidata.org/wiki/Q420
concepts[2].display_name	Biology
concepts[3].id	https://openalex.org/C2992459734
concepts[3].level	3
concepts[3].score	0.44963523745536804
concepts[3].wikidata	https://www.wikidata.org/wiki/Q43054
concepts[3].display_name	Neural cell
concepts[4].id	https://openalex.org/C169760540
concepts[4].level	1
concepts[4].score	0.43223845958709717
concepts[4].wikidata	https://www.wikidata.org/wiki/Q207011
concepts[4].display_name	Neuroscience
concepts[5].id	https://openalex.org/C189014844
concepts[5].level	3
concepts[5].score	0.4131307303905487
concepts[5].wikidata	https://www.wikidata.org/wiki/Q189118
concepts[5].display_name	Cell type
concepts[6].id	https://openalex.org/C28328180
concepts[6].level	2
concepts[6].score	0.3877713978290558
concepts[6].wikidata	https://www.wikidata.org/wiki/Q48196
concepts[6].display_name	Stem cell
concepts[7].id	https://openalex.org/C70721500
concepts[7].level	1
concepts[7].score	0.37671875953674316
concepts[7].wikidata	https://www.wikidata.org/wiki/Q177005
concepts[7].display_name	Computational biology
concepts[8].id	https://openalex.org/C41008148
concepts[8].level	0
concepts[8].score	0.35494059324264526
concepts[8].wikidata	https://www.wikidata.org/wiki/Q21198
concepts[8].display_name	Computer science
concepts[9].id	https://openalex.org/C1491633281
concepts[9].level	2
concepts[9].score	0.29873326420783997
concepts[9].wikidata	https://www.wikidata.org/wiki/Q7868
concepts[9].display_name	Cell
concepts[10].id	https://openalex.org/C95444343
concepts[10].level	1
concepts[10].score	0.24480175971984863
concepts[10].wikidata	https://www.wikidata.org/wiki/Q7141
concepts[10].display_name	Cell biology
concepts[11].id	https://openalex.org/C145103041
concepts[11].level	3
concepts[11].score	0.22428929805755615
concepts[11].wikidata	https://www.wikidata.org/wiki/Q1151519
concepts[11].display_name	Embryonic stem cell
concepts[12].id	https://openalex.org/C54355233
concepts[12].level	1
concepts[12].score	0.06378519535064697
concepts[12].wikidata	https://www.wikidata.org/wiki/Q7162
concepts[12].display_name	Genetics
concepts[13].id	https://openalex.org/C104317684
concepts[13].level	2
concepts[13].score	0.0
concepts[13].wikidata	https://www.wikidata.org/wiki/Q7187
concepts[13].display_name	Gene
keywords[0].id	https://openalex.org/keywords/induced-pluripotent-stem-cell
keywords[0].score	0.7627434730529785
keywords[0].display_name	Induced pluripotent stem cell
keywords[1].id	https://openalex.org/keywords/neural-stem-cell
keywords[1].score	0.6313843131065369
keywords[1].display_name	Neural stem cell
keywords[2].id	https://openalex.org/keywords/biology
keywords[2].score	0.5147700309753418
keywords[2].display_name	Biology
keywords[3].id	https://openalex.org/keywords/neural-cell
keywords[3].score	0.44963523745536804
keywords[3].display_name	Neural cell
keywords[4].id	https://openalex.org/keywords/neuroscience
keywords[4].score	0.43223845958709717
keywords[4].display_name	Neuroscience
keywords[5].id	https://openalex.org/keywords/cell-type
keywords[5].score	0.4131307303905487
keywords[5].display_name	Cell type
keywords[6].id	https://openalex.org/keywords/stem-cell
keywords[6].score	0.3877713978290558
keywords[6].display_name	Stem cell
keywords[7].id	https://openalex.org/keywords/computational-biology
keywords[7].score	0.37671875953674316
keywords[7].display_name	Computational biology
keywords[8].id	https://openalex.org/keywords/computer-science
keywords[8].score	0.35494059324264526
keywords[8].display_name	Computer science
keywords[9].id	https://openalex.org/keywords/cell
keywords[9].score	0.29873326420783997
keywords[9].display_name	Cell
keywords[10].id	https://openalex.org/keywords/cell-biology
keywords[10].score	0.24480175971984863
keywords[10].display_name	Cell biology
keywords[11].id	https://openalex.org/keywords/embryonic-stem-cell
keywords[11].score	0.22428929805755615
keywords[11].display_name	Embryonic stem cell
keywords[12].id	https://openalex.org/keywords/genetics
keywords[12].score	0.06378519535064697
keywords[12].display_name	Genetics
language	en
locations[0].id	doi:10.1007/978-1-4939-9007-8_5
locations[0].is_oa	False
locations[0].source.id	https://openalex.org/S4210172139
locations[0].source.issn	1064-3745, 1940-6029
locations[0].source.type	book series
locations[0].source.is_oa	False
locations[0].source.issn_l	1064-3745
locations[0].source.is_core	True
locations[0].source.is_in_doaj	False
locations[0].source.display_name	Methods in molecular biology
locations[0].source.host_organization	https://openalex.org/P4310319900
locations[0].source.host_organization_name	Springer Science+Business Media
locations[0].source.host_organization_lineage	https://openalex.org/P4310319900
locations[0].license
locations[0].pdf_url
locations[0].version	publishedVersion
locations[0].raw_type	book-chapter
locations[0].license_id
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Methods in Molecular Biology
locations[0].landing_page_url	https://doi.org/10.1007/978-1-4939-9007-8_5
locations[1].id	pmid:30656621
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	Methods in molecular biology (Clifton, N.J.)
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/30656621
locations[2].id	pmh:oai:pubmedcentral.nih.gov:6908303
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S2764455111
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	PubMed Central
locations[2].source.host_organization	https://openalex.org/I1299303238
locations[2].source.host_organization_name	National Institutes of Health
locations[2].source.host_organization_lineage	https://openalex.org/I1299303238
locations[2].license
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	Text
locations[2].license_id
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name	Methods Mol Biol
locations[2].landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/6908303
indexed_in	crossref, pubmed
authorships[0].author.id	https://openalex.org/A5100401933
authorships[0].author.orcid	https://orcid.org/0000-0001-5438-7309
authorships[0].author.display_name	Yu Chen
authorships[0].countries	US
authorships[0].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[0].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[0].institutions[0].id	https://openalex.org/I4210148682
authorships[0].institutions[0].ror	https://ror.org/04pw6fb54
authorships[0].institutions[0].type	government
authorships[0].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[0].institutions[0].country_code	US
authorships[0].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[0].author_position	first
authorships[0].raw_author_name	Yu Chen
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[1].author.id	https://openalex.org/A5108551287
authorships[1].author.orcid
authorships[1].author.display_name	Carlos A. Tristan
authorships[1].countries	US
authorships[1].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[1].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[1].institutions[0].id	https://openalex.org/I4210148682
authorships[1].institutions[0].ror	https://ror.org/04pw6fb54
authorships[1].institutions[0].type	government
authorships[1].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[1].institutions[0].country_code	US
authorships[1].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[1].author_position	middle
authorships[1].raw_author_name	Carlos A. Tristan
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[2].author.id	https://openalex.org/A5004768325
authorships[2].author.orcid
authorships[2].author.display_name	Sunil K. Mallanna
authorships[2].countries	US
authorships[2].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[2].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[2].institutions[0].id	https://openalex.org/I4210148682
authorships[2].institutions[0].ror	https://ror.org/04pw6fb54
authorships[2].institutions[0].type	government
authorships[2].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[2].institutions[0].country_code	US
authorships[2].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[2].author_position	middle
authorships[2].raw_author_name	Sunil K. Mallanna
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[3].author.id	https://openalex.org/A5060422349
authorships[3].author.orcid	https://orcid.org/0000-0002-2384-8253
authorships[3].author.display_name	Pinar Ormanoglu
authorships[3].countries	US
authorships[3].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[3].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[3].institutions[0].id	https://openalex.org/I4210148682
authorships[3].institutions[0].ror	https://ror.org/04pw6fb54
authorships[3].institutions[0].type	government
authorships[3].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[3].institutions[0].country_code	US
authorships[3].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[3].author_position	middle
authorships[3].raw_author_name	Pinar Ormanoglu
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[4].author.id	https://openalex.org/A5079961784
authorships[4].author.orcid
authorships[4].author.display_name	Steven A. Titus
authorships[4].countries	US
authorships[4].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[4].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[4].institutions[0].id	https://openalex.org/I4210148682
authorships[4].institutions[0].ror	https://ror.org/04pw6fb54
authorships[4].institutions[0].type	government
authorships[4].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[4].institutions[0].country_code	US
authorships[4].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[4].author_position	middle
authorships[4].raw_author_name	Steven Titus
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[5].author.id	https://openalex.org/A5059969497
authorships[5].author.orcid	https://orcid.org/0000-0002-4523-9977
authorships[5].author.display_name	Anton Simeonov
authorships[5].countries	US
authorships[5].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[5].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[5].institutions[0].id	https://openalex.org/I4210148682
authorships[5].institutions[0].ror	https://ror.org/04pw6fb54
authorships[5].institutions[0].type	government
authorships[5].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[5].institutions[0].country_code	US
authorships[5].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[5].author_position	middle
authorships[5].raw_author_name	Anton Simeonov
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[6].author.id	https://openalex.org/A5039701907
authorships[6].author.orcid	https://orcid.org/0000-0003-3941-1838
authorships[6].author.display_name	Ilyas Singeç
authorships[6].countries	US
authorships[6].affiliations[0].institution_ids	https://openalex.org/I4210148682
authorships[6].affiliations[0].raw_affiliation_string	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
authorships[6].institutions[0].id	https://openalex.org/I4210148682
authorships[6].institutions[0].ror	https://ror.org/04pw6fb54
authorships[6].institutions[0].type	government
authorships[6].institutions[0].lineage	https://openalex.org/I1299022934, https://openalex.org/I1299303238, https://openalex.org/I4210148682
authorships[6].institutions[0].country_code	US
authorships[6].institutions[0].display_name	National Center for Advancing Translational Sciences
authorships[6].author_position	last
authorships[6].raw_author_name	Ilyas Singeç
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Stem Cell Translation Laboratory (SCTL), Division of Pre-Clinical Innovation, NIH National Center for Advancing Translational Sciences (NCATS), NIH Regenerative Medicine Program, Rockville, MD, USA
has_content.pdf	False
has_content.grobid_xml	False
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://www.ncbi.nlm.nih.gov/pmc/articles/6908303
open_access.oa_status	green
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Chemically Defined Neural Conversion of Human Pluripotent Stem Cells
has_fulltext	False
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T10505
primary_topic.field.id	https://openalex.org/fields/13
primary_topic.field.display_name	Biochemistry, Genetics and Molecular Biology
primary_topic.score	0.9998000264167786
primary_topic.domain.id	https://openalex.org/domains/1
primary_topic.domain.display_name	Life Sciences
primary_topic.subfield.id	https://openalex.org/subfields/1312
primary_topic.subfield.display_name	Molecular Biology
primary_topic.display_name	Pluripotent Stem Cells Research
related_works	https://openalex.org/W2116440, https://openalex.org/W2083242763, https://openalex.org/W2913674026, https://openalex.org/W2972837166, https://openalex.org/W1980489702, https://openalex.org/W2534960771, https://openalex.org/W2374476619, https://openalex.org/W341309029, https://openalex.org/W2387427554, https://openalex.org/W4312195844
cited_by_count	1
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	1
locations_count	3
best_oa_location.id	pmh:oai:pubmedcentral.nih.gov:6908303
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S2764455111
best_oa_location.source.issn
best_oa_location.source.type	repository
best_oa_location.source.is_oa	False
best_oa_location.source.issn_l
best_oa_location.source.is_core	False
best_oa_location.source.is_in_doaj	False
best_oa_location.source.display_name	PubMed Central
best_oa_location.source.host_organization	https://openalex.org/I1299303238
best_oa_location.source.host_organization_name	National Institutes of Health
best_oa_location.source.host_organization_lineage	https://openalex.org/I1299303238
best_oa_location.license
best_oa_location.pdf_url
best_oa_location.version	submittedVersion
best_oa_location.raw_type	Text
best_oa_location.license_id
best_oa_location.is_accepted	False
best_oa_location.is_published	False
best_oa_location.raw_source_name	Methods Mol Biol
best_oa_location.landing_page_url	https://www.ncbi.nlm.nih.gov/pmc/articles/6908303
primary_location.id	doi:10.1007/978-1-4939-9007-8_5
primary_location.is_oa	False
primary_location.source.id	https://openalex.org/S4210172139
primary_location.source.issn	1064-3745, 1940-6029
primary_location.source.type	book series
primary_location.source.is_oa	False
primary_location.source.issn_l	1064-3745
primary_location.source.is_core	True
primary_location.source.is_in_doaj	False
primary_location.source.display_name	Methods in molecular biology
primary_location.source.host_organization	https://openalex.org/P4310319900
primary_location.source.host_organization_name	Springer Science+Business Media
primary_location.source.host_organization_lineage	https://openalex.org/P4310319900
primary_location.license
primary_location.pdf_url
primary_location.version	publishedVersion
primary_location.raw_type	book-chapter
primary_location.license_id
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Methods in Molecular Biology
primary_location.landing_page_url	https://doi.org/10.1007/978-1-4939-9007-8_5
publication_date	2019-01-01
publication_year	2019
referenced_works	https://openalex.org/W2086943348, https://openalex.org/W2138977668, https://openalex.org/W2039824179, https://openalex.org/W2033284482, https://openalex.org/W2148633182, https://openalex.org/W2152069828, https://openalex.org/W1966476278, https://openalex.org/W2111191613, https://openalex.org/W2060299616, https://openalex.org/W2062849851, https://openalex.org/W1994758141, https://openalex.org/W2172111284, https://openalex.org/W2067163479, https://openalex.org/W2087786585, https://openalex.org/W2513089819, https://openalex.org/W2110301828, https://openalex.org/W1982960471, https://openalex.org/W2038723730, https://openalex.org/W2006557127, https://openalex.org/W2075655507, https://openalex.org/W2074744546, https://openalex.org/W1996659151, https://openalex.org/W2077062756, https://openalex.org/W1560236760, https://openalex.org/W2751596777, https://openalex.org/W2281224598
referenced_works_count	26
abstract_inverted_index
cited_by_percentile_year.max	95
cited_by_percentile_year.min	91
countries_distinct_count	1
institutions_distinct_count	7
sustainable_development_goals[0].id	https://metadata.un.org/sdg/9
sustainable_development_goals[0].score	0.5799999833106995
sustainable_development_goals[0].display_name	Industry, innovation and infrastructure
citation_normalized_percentile.value	0.02256687
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False