ChronQC: a quality control monitoring system for clinical next generation sequencing Article Swipe
YOU?
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· 2017
· Open Access
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· DOI: https://doi.org/10.1093/bioinformatics/btx843
Summary ChronQC is a quality control (QC) tracking system for clinical implementation of next-generation sequencing (NGS). ChronQC generates time series plots for various QC metrics to allow comparison of current runs to historical runs. ChronQC has multiple features for tracking QC data including Westgard rules for clinical validity, laboratory-defined thresholds and historical observations within a specified time period. Users can record their notes and corrective actions directly onto the plots for long-term recordkeeping. ChronQC facilitates regular monitoring of clinical NGS to enable adherence to high quality clinical standards. Availability and implementation ChronQC is freely available on GitHub (https://github.com/nilesh-tawari/ChronQC), Docker (https://hub.docker.com/r/nileshtawari/chronqc/) and the Python Package Index. ChronQC is implemented in Python and runs on all common operating systems (Windows, Linux and Mac OS X). Supplementary information Supplementary data are available at Bioinformatics online.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/bioinformatics/btx843
- https://academic.oup.com/bioinformatics/article-pdf/34/10/1799/25118254/btx843.pdf
- OA Status
- bronze
- Cited By
- 3
- References
- 5
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2778576074
Raw OpenAlex JSON
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https://openalex.org/W2778576074Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/bioinformatics/btx843Digital Object Identifier
- Title
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ChronQC: a quality control monitoring system for clinical next generation sequencingWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2017Year of publication
- Publication date
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2017-12-27Full publication date if available
- Authors
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Nilesh R. Tawari, Justine Jia Wen Seow, Perumal Dharuman, Jack Ling Ow, Shimin Ang, Arun George Devasia, Pauline C. NgList of authors in order
- Landing page
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https://doi.org/10.1093/bioinformatics/btx843Publisher landing page
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https://academic.oup.com/bioinformatics/article-pdf/34/10/1799/25118254/btx843.pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://academic.oup.com/bioinformatics/article-pdf/34/10/1799/25118254/btx843.pdfDirect OA link when available
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Python (programming language), Computer science, Operating system, Software, Data mining, Real-time computingTop concepts (fields/topics) attached by OpenAlex
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3Total citation count in OpenAlex
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2025: 1, 2023: 1, 2019: 1Per-year citation counts (last 5 years)
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5Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| best_oa_location.landing_page_url | https://doi.org/10.1093/bioinformatics/btx843 |
| primary_location.id | doi:10.1093/bioinformatics/btx843 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S52395412 |
| primary_location.source.issn | 1367-4803, 1367-4811 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 1367-4803 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Bioinformatics |
| primary_location.source.host_organization | https://openalex.org/P4310311648 |
| primary_location.source.host_organization_name | Oxford University Press |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310311648, https://openalex.org/P4310311647 |
| primary_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| primary_location.license | |
| primary_location.pdf_url | https://academic.oup.com/bioinformatics/article-pdf/34/10/1799/25118254/btx843.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Bioinformatics |
| primary_location.landing_page_url | https://doi.org/10.1093/bioinformatics/btx843 |
| publication_date | 2017-12-27 |
| publication_year | 2017 |
| referenced_works | https://openalex.org/W2607658156, https://openalex.org/W2432815617, https://openalex.org/W2111281047, https://openalex.org/W2514978364, https://openalex.org/W2109194250 |
| referenced_works_count | 5 |
| abstract_inverted_index.a | 4, 55 |
| abstract_inverted_index.OS | 122 |
| abstract_inverted_index.QC | 24, 41 |
| abstract_inverted_index.at | 130 |
| abstract_inverted_index.in | 109 |
| abstract_inverted_index.is | 3, 93, 107 |
| abstract_inverted_index.of | 13, 29, 78 |
| abstract_inverted_index.on | 96, 113 |
| abstract_inverted_index.to | 26, 32, 81, 84 |
| abstract_inverted_index.Mac | 121 |
| abstract_inverted_index.NGS | 80 |
| abstract_inverted_index.X). | 123 |
| abstract_inverted_index.all | 114 |
| abstract_inverted_index.and | 51, 64, 90, 101, 111, 120 |
| abstract_inverted_index.are | 128 |
| abstract_inverted_index.can | 60 |
| abstract_inverted_index.for | 10, 22, 39, 46, 71 |
| abstract_inverted_index.has | 36 |
| abstract_inverted_index.the | 69, 102 |
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| abstract_inverted_index.data | 42, 127 |
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| abstract_inverted_index.runs | 31, 112 |
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| abstract_inverted_index.Linux | 119 |
| abstract_inverted_index.Users | 59 |
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| abstract_inverted_index.notes | 63 |
| abstract_inverted_index.plots | 21, 70 |
| abstract_inverted_index.rules | 45 |
| abstract_inverted_index.runs. | 34 |
| abstract_inverted_index.their | 62 |
| abstract_inverted_index.(NGS). | 16 |
| abstract_inverted_index.Docker | 99 |
| abstract_inverted_index.GitHub | 97 |
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| abstract_inverted_index.Python | 103, 110 |
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| abstract_inverted_index.series | 20 |
| abstract_inverted_index.system | 9 |
| abstract_inverted_index.within | 54 |
| abstract_inverted_index.ChronQC | 2, 17, 35, 74, 92, 106 |
| abstract_inverted_index.Package | 104 |
| abstract_inverted_index.Summary | 1 |
| abstract_inverted_index.actions | 66 |
| abstract_inverted_index.control | 6 |
| abstract_inverted_index.current | 30 |
| abstract_inverted_index.metrics | 25 |
| abstract_inverted_index.online. | 132 |
| abstract_inverted_index.period. | 58 |
| abstract_inverted_index.quality | 5, 86 |
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| abstract_inverted_index.Abstract | 0 |
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| abstract_inverted_index.clinical | 11, 47, 79, 87 |
| abstract_inverted_index.directly | 67 |
| abstract_inverted_index.features | 38 |
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| abstract_inverted_index.tracking | 8, 40 |
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| abstract_inverted_index.including | 43 |
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| abstract_inverted_index.sequencing | 15 |
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| abstract_inverted_index.implemented | 108 |
| abstract_inverted_index.information | 125 |
| abstract_inverted_index.Availability | 89 |
| abstract_inverted_index.observations | 53 |
| abstract_inverted_index.Supplementary | 124, 126 |
| abstract_inverted_index.Bioinformatics | 131 |
| abstract_inverted_index.implementation | 12, 91 |
| abstract_inverted_index.recordkeeping. | 73 |
| abstract_inverted_index.next-generation | 14 |
| abstract_inverted_index.laboratory-defined | 49 |
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| abstract_inverted_index.(https://hub.docker.com/r/nileshtawari/chronqc/) | 100 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5101740308, https://openalex.org/A5077106450 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 7 |
| corresponding_institution_ids | https://openalex.org/I66068411 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/9 |
| sustainable_development_goals[0].score | 0.4099999964237213 |
| sustainable_development_goals[0].display_name | Industry, innovation and infrastructure |
| citation_normalized_percentile.value | 0.45561264 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |