CircMORC1 downregulated in plasma EVs promotes gastric cancer cell proliferation and invasion via miR-103a-1-5p sponging Article Swipe
Xiang-Ming Zhai
,
Yiqi Yang
,
Li Lin
,
Hao Luo
,
Zhiwei Guo
,
Ying-Song Wu
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12885-025-14688-7
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1186/s12885-025-14688-7
Our results shed light on circMORC1 promotes the proliferation of gastric cancer cells, as a RNA sponge of miR-103a-1-5p and counteracted the down-regulation of Wnt signaling function of miR-103a-1-5p. Revealed a novel mechanism by which circMORC1 regulates tumorigenesis in gastric cancer and provided a new biomarker for GC diagnosis and prognosis.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12885-025-14688-7
- OA Status
- gold
- References
- 33
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413118166
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4413118166Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s12885-025-14688-7Digital Object Identifier
- Title
-
CircMORC1 downregulated in plasma EVs promotes gastric cancer cell proliferation and invasion via miR-103a-1-5p spongingWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-08-13Full publication date if available
- Authors
-
Xiang-Ming Zhai, Yiqi Yang, Li Lin, Hao Luo, Zhiwei Guo, Ying-Song WuList of authors in order
- Landing page
-
https://doi.org/10.1186/s12885-025-14688-7Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1186/s12885-025-14688-7Direct OA link when available
- Concepts
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Wnt signaling pathway, microRNA, Carcinogenesis, Cancer, Biology, Cell growth, Cancer research, Apoptosis, Cell biology, Cancer cell, Signal transduction, Gene, GeneticsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
- References (count)
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33Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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