CircRNAs: a novel potential strategy to treat breast cancer Article Swipe
Pangzhou Chen
,
Jinhui Zhang
,
Song Wu
,
Xiaoyu Zhang
,
Wenxia Zhou
,
Ziyun Guan
,
Hailin Tang
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fimmu.2025.1563655
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.3389/fimmu.2025.1563655
Breast cancer is among the most prevalent malignant tumors worldwide, with triple-negative breast cancer (TNBC) being the most aggressive subtype and lacking effective treatment options. Circular RNAs (circRNAs) are noncoding RNAs that play crucial roles in the development of tumors, including breast cancer. This article examines the progress of research on circRNAs in breast cancer, focusing on four main areas: 1) breast cancer epidemiology, classification, and treatment; 2) the structure, discovery process, characteristics, formation, and functions of circRNAs; 3) the expression, mechanisms, clinical relevance, and recent advances in the study of circRNAs in breast cancer cells and the immune microenvironment, particularly in TNBC; and 4) the challenges and future prospects of the use of circRNAs in BC research.
Related Topics
Concepts
Breast cancer
Cancer
Triple-negative breast cancer
Computational biology
Immune system
Medicine
Bioinformatics
Cancer research
Biology
Immunology
Internal medicine
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.3389/fimmu.2025.1563655
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1563655/pdf
- OA Status
- gold
- Cited By
- 3
- References
- 165
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4408642518
All OpenAlex metadata
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https://openalex.org/W4408642518Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3389/fimmu.2025.1563655Digital Object Identifier
- Title
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CircRNAs: a novel potential strategy to treat breast cancerWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-03-19Full publication date if available
- Authors
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Pangzhou Chen, Jinhui Zhang, Song Wu, Xiaoyu Zhang, Wenxia Zhou, Ziyun Guan, Hailin TangList of authors in order
- Landing page
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https://doi.org/10.3389/fimmu.2025.1563655Publisher landing page
- PDF URL
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https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1563655/pdfDirect link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
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https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1563655/pdfDirect OA link when available
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Breast cancer, Cancer, Triple-negative breast cancer, Computational biology, Immune system, Medicine, Bioinformatics, Cancer research, Biology, Immunology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
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3Total citation count in OpenAlex
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2025: 3Per-year citation counts (last 5 years)
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165Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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