Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic Fibrosis Article Swipe
YOU?
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· 2021
· Open Access
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· DOI: https://doi.org/10.1044/2021_aja-21-00031
Purpose Specific classes of antibiotics, such as aminoglycosides, have well-established adverse events producing permanent hearing loss, tinnitus, and balance and/or vestibular problems (i.e., ototoxicity). Although these antibiotics are frequently used to treat pseudomonas and other bacterial infections in patients with cystic fibrosis (CF), there are no formalized recommendations describing approaches to implementation of guideline adherent ototoxicity monitoring as part of CF clinical care. Method This consensus statement was developed by the International Ototoxicity Management Working Group (IOMG) Ad Hoc Committee on Aminoglycoside Antibiotics to address the clinical need for ototoxicity management in CF patients treated with known ototoxic medications. These clinical protocol considerations were created using consensus opinion from a community of international experts and available evidence specific to patients with CF, as well as published national and international guidelines on ototoxicity monitoring. Results The IOMG advocates four clinical recommendations for implementing routine and guideline adherent ototoxicity management in patients with CF. These are (a) including questions about hearing, tinnitus, and balance/vestibular problems as part of the routine CF case history for all patients; (b) utilizing timely point-of-care measures; (c) establishing a baseline and conducting posttreatment evaluations for each course of intravenous ototoxic drug treatment; and (d) repeating annual hearing and vestibular evaluations for all patients with a history of ototoxic antibiotic exposure. Conclusion Increased efforts for implementation of an ototoxicity management program in the CF care team model will improve identification of ototoxicity signs and symptoms, allow for timely therapeutic follow-up, and provide the clinician and patient an opportunity to make an informed decision about potential treatment modifications to minimize adverse events. Supplemental Material https://doi.org/10.23641/asha.16624366
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1044/2021_aja-21-00031
- OA Status
- green
- Cited By
- 18
- References
- 51
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3171315413
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3171315413Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1044/2021_aja-21-00031Digital Object Identifier
- Title
-
Clinical Considerations for Routine Auditory and Vestibular Monitoring in Patients With Cystic FibrosisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-09-22Full publication date if available
- Authors
-
Angela C. Garinis, Gayla L. Poling, Ronald C. Rubenstein, Dawn Konrad‐Martin, Timothy E. Hullar, David Baguley, Holly Burrows, Jennifer Chisholm, Amy Custer, Laura Dreisbach Hawe, Lisa L. Hunter, Theodore K. Marras, Candice E. Ortiz, Lucretia Petersen, Peter S. Steyger, Kevin Winthrop, Erika M. Zettner, Khaya D. Clark, Michelle Hungerford, Jay J. Vachhani, Carmen C. BrewerList of authors in order
- Landing page
-
https://doi.org/10.1044/2021_aja-21-00031Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://nottingham-repository.worktribe.com/output/5576855Direct OA link when available
- Concepts
-
Ototoxicity, Medicine, Tinnitus, Guideline, Intensive care medicine, Cystic fibrosis, Audiology, Hearing loss, Internal medicine, Pathology, Chemotherapy, CisplatinTop concepts (fields/topics) attached by OpenAlex
- Cited by
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18Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 5, 2024: 5, 2023: 2, 2022: 3, 2021: 3Per-year citation counts (last 5 years)
- References (count)
-
51Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.intravenous | 191 |
| abstract_inverted_index.monitoring. | 132 |
| abstract_inverted_index.opportunity | 249 |
| abstract_inverted_index.ototoxicity | 55, 89, 131, 146, 220, 233 |
| abstract_inverted_index.pseudomonas | 32 |
| abstract_inverted_index.therapeutic | 240 |
| abstract_inverted_index.Supplemental | 263 |
| abstract_inverted_index.antibiotics, | 4 |
| abstract_inverted_index.establishing | 180 |
| abstract_inverted_index.implementing | 141 |
| abstract_inverted_index.medications. | 98 |
| abstract_inverted_index.International | 71 |
| abstract_inverted_index.international | 112, 128 |
| abstract_inverted_index.modifications | 258 |
| abstract_inverted_index.ototoxicity). | 23 |
| abstract_inverted_index.point-of-care | 177 |
| abstract_inverted_index.posttreatment | 185 |
| abstract_inverted_index.Aminoglycoside | 81 |
| abstract_inverted_index.considerations | 102 |
| abstract_inverted_index.identification | 231 |
| abstract_inverted_index.implementation | 51, 217 |
| abstract_inverted_index.recommendations | 47, 139 |
| abstract_inverted_index.aminoglycosides, | 7 |
| abstract_inverted_index.well-established | 9 |
| abstract_inverted_index.balance/vestibular | 161 |
| abstract_inverted_index.https://doi.org/10.23641/asha.16624366 | 265 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 94 |
| countries_distinct_count | 4 |
| institutions_distinct_count | 21 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/17 |
| sustainable_development_goals[0].score | 0.4000000059604645 |
| sustainable_development_goals[0].display_name | Partnerships for the goals |
| citation_normalized_percentile.value | 0.81427487 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |