Clinical outcomes and prognostic factors of head and neck squamous cell carcinoma: a ten-year follow-up study Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.1590/1807-3107bor-2023.vol37.0128
Traditional guidelines for determining the prognosis of patients with head and neck squamous cell carcinoma (HNSCC) are used to make therapeutic decisions. However, only 50% of the patients had lived for more than five years. The present study aimed to analyze the correlation of traditional prognostic factors such as tumor size, histological grading, regional metastases, and treatment with the survival of patients with HNSCC. A total of 78 patients diagnosed with HNSCC were followed up for 10 years after diagnosis and treatment. The health status of the patients was tracked at four time points, and according to the evolution of the patients and their final clinical status, we performed a prognostic analysis based on the clinical outcomes observed during the follow-up period. The final study cohort comprised 50 patients. Most patients had tumors < 4 cm in size (64%) and no regional metastases (64%); no patients had distant metastases at the time of diagnosis. Most individuals had tumors with good (48%) and moderate (46%) degrees of malignancy. At the end of the follow-up period, only 14% of the patients were discharged, 42% died of the tumor, and 44% remained under observation owing to the presence of a potentially malignant disorder, relapse, or metastases. This analysis showed that traditional prognostic factors were not accurate in detecting subclinical changes or predicting the clinical evolution of patients.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- http://doi.org/10.1590/1807-3107bor-2023.vol37.0128
- OA Status
- diamond
- Cited By
- 2
- References
- 23
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4389782198
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4389782198Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1590/1807-3107bor-2023.vol37.0128Digital Object Identifier
- Title
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Clinical outcomes and prognostic factors of head and neck squamous cell carcinoma: a ten-year follow-up studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-01-01Full publication date if available
- Authors
-
Kelly Bienk DIAS, Laura de Campos Hildebrand, Ana Luísa Carvalho, Camila Alves Ferri, Jacques E. Nör, Carlos Thadeu Schmidt Cerski, Fernanda Visioli, Márcia Gaiger de Oliveira, Pantelis Varvaki RadosList of authors in order
- Landing page
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https://doi.org/10.1590/1807-3107bor-2023.vol37.0128Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1590/1807-3107bor-2023.vol37.0128Direct OA link when available
- Concepts
-
Medicine, Subclinical infection, Grading (engineering), Internal medicine, Head and neck squamous-cell carcinoma, Malignancy, Oncology, Cohort, Head and neck, Radiation therapy, Head and neck cancer, Basal cell, Radiology, Surgery, Engineering, Civil engineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
- Citations by year (recent)
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2025: 2Per-year citation counts (last 5 years)
- References (count)
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23Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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