Cognition and neuropsychiatry in behavioral variant frontotemporal dementia by disease stage Article Swipe

PDF

Related Concepts

Frontotemporal dementia Dementia Psychology Episodic memory Clinical Dementia Rating Verbal fluency test Cognition Neuropsychology Cognitive decline Semantic dementia Cohort Disease Boston Naming Test Audiology Alzheimer's disease Psychiatry Medicine Cognitive impairment Internal medicine

Kamalini G. Ranasinghe , Katherine P. Rankin , Iryna Lobach , Joel H. Kramer , Virginia E. Sturm , Brianne M. Bettcher , Katherine L. Possin , S. Christine You , Amanda K. LaMarre , Tal Shany‐Ur , Melanie Stephens , David C. Perry , Suzee E. Lee , Zachary Miller , Maria Luisa Gorno‐Tempini , Howard J. Rosen , Adam L. Boxer , William W. Seeley , Gil D. Rabinovici , Keith Vossel , Bruce L. Miller ·

YOU? · · 2016 · Open Access · · DOI: https://doi.org/10.1212/wnl.0000000000002373 · OA: W2304803376

There are distinct patterns of cognitive deficits differentiating the earlier and later disease stages in bvFTD, with the pattern of cognitive decline revealing in greater detail the natural history of the disease. These cognitive symptoms are readily apparent clinical markers of dysfunction in the principal brain networks known to undergo molecular and anatomical changes in bvFTD, thus are important indicators of the evolving pathology in individual patients.