Comment on “Circadian rhythms in the absence of the clock gene Bmal1 ” Article Swipe
Related Concepts
Circadian rhythm
Rhythm
Genotype
Biology
Messenger RNA
CLOCK
Circadian clock
Gene
Endocrinology
Genetics
Internal medicine
Medicine
Katharine C. Abruzzi
,
Cédric Gobet
,
Félix Naef
,
Michael Rosbash
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1126/science.abf0922
· OA: W3156115256
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1126/science.abf0922
· OA: W3156115256
Ray et al . (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in Bmal1 –/– liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations in this genotype. We also note errors and potentially inappropriate analyses.
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