Comparative Evaluation of Safety and Efficacy of Different Sedation Protocols in Pediatric Dental Procedures: An Original Research Article Swipe
Anindita Talukdar
,
Mona Malekzadeh
,
Amrita Mishra
,
Abinash Mohapatra
,
Pooja Varma
,
Abhishek Jahagirdar
,
Mohammed M. Khan
,
Roland Reuben B. Angeles
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4103/jpbs.jpbs_1845_24
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4103/jpbs.jpbs_1845_24
A BSTRACT Objective: This study aimed to compare the efficacy and safety of different sedation protocols commonly used in pediatric dental procedures, specifically focusing on Midazolam and Dexmedetomidine. Methods: A retrospective comparative study was conducted on pediatric patients undergoing dental procedures under sedation. Three sedation protocols (Midazolam, Dexmedetomidine, and Midazolam–Ketamine combination) were evaluated. The primary outcomes assessed were sedation efficacy, patient cooperation, and side effects. Statistical analyses were conducted to determine differences between groups. Results: The study demonstrated significant differences in sedation efficacy and patient cooperation between the protocols. Dexmedetomidine showed superior efficacy in maintaining stable sedation levels and minimizing adverse reactions compared to Midazolam. The combination of Midazolam and Ketamine provided a quicker onset but was associated with a higher incidence of side effects. Conclusion: Dexmedetomidine is a safer and more effective sedation option for pediatric dental procedures compared to Midazolam and its combination with Ketamine. Further randomized controlled trials are recommended to confirm these findings.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4103/jpbs.jpbs_1845_24
- OA Status
- gold
- References
- 16
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4411538544
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4411538544Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.4103/jpbs.jpbs_1845_24Digital Object Identifier
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Comparative Evaluation of Safety and Efficacy of Different Sedation Protocols in Pediatric Dental Procedures: An Original ResearchWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-06-23Full publication date if available
- Authors
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Anindita Talukdar, Mona Malekzadeh, Amrita Mishra, Abinash Mohapatra, Pooja Varma, Abhishek Jahagirdar, Mohammed M. Khan, Roland Reuben B. AngelesList of authors in order
- Landing page
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https://doi.org/10.4103/jpbs.jpbs_1845_24Publisher landing page
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.4103/jpbs.jpbs_1845_24Direct OA link when available
- Concepts
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Dexmedetomidine, Midazolam, Sedation, Medicine, Ketamine, Anesthesia, Randomized controlled trial, Clinical trial, Adverse effect, Incidence (geometry), Surgery, Pharmacology, Internal medicine, Optics, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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16Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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