Comparative genomics of CXCR4MUT and CXCR4WT single cells in Waldenström’s macroglobulinemia Article Swipe
Related Concepts
Macroglobulinemia
Waldenstrom macroglobulinemia
Genomics
Biology
Genome
Computational biology
Gene
Genetics
Multiple myeloma
Immunology
Lymphoma
Cristina Jiménez
,
Lian Xu
,
Nickolas Tsakmaklis
,
Maria Demos
,
Amanda Kofides
,
Gloria Chan
,
Maria Luisa Guerrera
,
Jiaji G. Chen
,
Xia Liu
,
Manit Munshi
,
Christopher J. Patterson
,
Guang Yang
,
Jorge J. Castillo
,
Steven P. Treon
,
Zachary R. Hunter
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1182/bloodadvances.2020001775
· OA: W3087285229
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1182/bloodadvances.2020001775
· OA: W3087285229
Key Points Single-cell whole-genome amplification can be used to interrogate the genomic architecture of Waldenström’s macroglobulinemia. The mutational signature of CXCR4MUT cells may be associated with alterations in DNA repairing genes and tumor suppressors.
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