Comparison of clinical profiles and care for patients with incident versus recurrent acute coronary syndromes in France: Data from the MONICA registries Article Swipe
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· 2022
· Open Access
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· DOI: https://doi.org/10.1371/journal.pone.0263589
Background Recurrence is common after an acute coronary syndrome (ACS). In order to better assess the prognosis for patients with ACS, we compared clinical profiles, treatments, and case fatality rates for incident vs. recurrent ACS. Methods We enrolled 1,459 men and women (age: 35–74) living in three geographical areas covered by French MONICA registries and who had been admitted to hospital for an ACS in 2015/2016. We recorded and compared the clinical characteristics and medical care for patients with an incident vs. a recurrent ACS. Results Overall, 431 (30%) had a recurrent ACS. Relative to patients with an incident ACS, patients with recurrence were older (p<0.0001), had a greater frequency of NSTEMI or UA (p<0.0001), were less likely to show typical symptoms (p = 0.045), were more likely to have an altered LVEF (p<0.0001) and co-morbidities. Angioplasty was less frequently performed among patients with recurrent than incident NSTEMI (p<0.05). There were no intergroup differences in the prescription of the recommended secondary prevention measures upon hospital discharge, except for functional rehabilitation more frequently prescribed among incident patients (p<0.0001). Although the crude 1-year mortality rate was higher for recurrent cases (14%) than for incident cases (8%) (p<0.05), this difference was no longer significant after adjustment for age, sex, region, diagnosis category and LVEF. Conclusion Compared with incident patients, recurrent cases were more likely to have co-morbidities and to have suboptimal treatments prior to hospital stay, reinforcing the need for secondary prevention.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pone.0263589
- https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263589&type=printable
- OA Status
- gold
- Cited By
- 5
- References
- 26
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4212770964
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4212770964Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1371/journal.pone.0263589Digital Object Identifier
- Title
-
Comparison of clinical profiles and care for patients with incident versus recurrent acute coronary syndromes in France: Data from the MONICA registriesWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-02-14Full publication date if available
- Authors
-
Suzanne Machta, Victoria Gauthier, Jean Ferrières, Michèle Montaye, S. Huo Yung Kai, S. Gbokou, Katia Biasch, Marie Moitry, Philippe Amouyel, Jean Dallongeville, Aline MeirhaegheList of authors in order
- Landing page
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https://doi.org/10.1371/journal.pone.0263589Publisher landing page
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263589&type=printableDirect link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
- OA URL
-
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0263589&type=printableDirect OA link when available
- Concepts
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Medicine, Acute coronary syndrome, Medical prescription, Internal medicine, Case fatality rate, Ejection fraction, Pediatrics, Myocardial infarction, Epidemiology, Heart failure, PharmacologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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5Total citation count in OpenAlex
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2025: 1, 2024: 1, 2023: 3Per-year citation counts (last 5 years)
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26Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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