Comparison of the Efficacy of Different Exercise Modes on MCI Adults: A Network Meta‐Analysis Article Swipe
Chengxuan Qiu
,
Jiaxin Han
,
Yao Xie
,
Lu Liu
,
Yufeng Zeng
,
Liangyi Xiao
,
Shanshan Zeng
,
Le Xie
,
Dahua Wu
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/brb3.70734
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/brb3.70734
Background Mild cognitive impairment (MCI) is considered a preclinical or prodromal stage of Alzheimer's disease (AD). MCI patients have an annual probability of progression to dementia of 10%–15%, far higher than the normal elderly (∼1%–2%). We conducted a network meta‐analysis (NMA) on the efficacy of various exercise modes on MCI adults. Methods A computer search was conducted in Embase, PubMed, the Cochrane Library, and Web of Science for RCTs on the effects of exercise training on MCI patients from their inception to February 22, 2025. Two reviewers were independently responsible for study screening, data extraction, and quality assessment. RevMan 5.4, Stata15, and R4.4.1 were utilized for data analysis. Results Thirty‐five studies with 2717 patients were included. The NMA results revealed that combination training (CT) performed best in increasing the MoCA and MMSE scores of MCI patients, with SUCRA of 99.43% and 87.04%, respectively. Resistance training and sensorimotor training were the second‐best interventions for increasing MMSE and MoCA scores, respectively. Conclusion CT is the best intervention to improve MOCA and MMSE scores in patients with MCI, which can effectively alleviate the disease progression of MCI. However, a variety of double‐blind, large‐sample clinical trials are still needed to further verify this conclusion.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1002/brb3.70734
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.70734
- OA Status
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- Cited By
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- References
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
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https://openalex.org/W4413478899Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1002/brb3.70734Digital Object Identifier
- Title
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Comparison of the Efficacy of Different Exercise Modes on MCI Adults: A Network Meta‐AnalysisWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2025Year of publication
- Publication date
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2025-08-01Full publication date if available
- Authors
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Chengxuan Qiu, Jiaxin Han, Yao Xie, Lu Liu, Yufeng Zeng, Liangyi Xiao, Shanshan Zeng, Le Xie, Dahua WuList of authors in order
- Landing page
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https://doi.org/10.1002/brb3.70734Publisher landing page
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.70734Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.70734Direct OA link when available
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Meta-analysis, Medicine, Physical medicine and rehabilitation, Psychology, Internal medicineTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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