Complete response to pembrolizumab plus chemotherapy in a case of unresectable advanced esophageal cancer Article Swipe
Tsuyoshi Ishii
,
Kazuhisa Yamaguchi
,
Ai Fujimoto
,
Yoshinori Kikuchi
,
Takahisa Matsuda
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.11641/pde.103.1_52
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.11641/pde.103.1_52
A 74-year-old woman visited our hospital with a chief complaint of anterior thoracic discomfort while eating. Esophagogastroduodenoscopy (EGD) revealed two type 2 neoplastic lesions in the 24 cm and 32 cm incisors. Squamous cell carcinoma was observed on histopathological examination. Contrast-enhanced CT showed lymph node and liver metastases, and cStage 4b (T3N3M1) was diagnosed. Ten courses of pembrolizumab plus chemotherapy were administered. Hepatotoxicity developed as an immune-related adverse event after the 10 courses but was resolved with prednisolone (1 mg/kg). Contrast-enhanced CT showed shrinkage of the lymph nodes and disappearance of the liver metastases. Scarring of both esophageal lesions appeared on EGD, and no cancer was detected. The response to the chemotherapy was considered to be complete. We report a rare case of complete response in a patient with unresectable esophageal cancer.
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- Type
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- Language
- en
- Landing Page
- https://doi.org/10.11641/pde.103.1_52
- OA Status
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- References
- 3
- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4390316934Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.11641/pde.103.1_52Digital Object Identifier
- Title
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Complete response to pembrolizumab plus chemotherapy in a case of unresectable advanced esophageal cancerWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-12-22Full publication date if available
- Authors
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Tsuyoshi Ishii, Kazuhisa Yamaguchi, Ai Fujimoto, Yoshinori Kikuchi, Takahisa MatsudaList of authors in order
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https://doi.org/10.11641/pde.103.1_52Publisher landing page
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YesWhether a free full text is available
- OA status
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diamondOpen access status per OpenAlex
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https://doi.org/10.11641/pde.103.1_52Direct OA link when available
- Concepts
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Medicine, Pembrolizumab, Esophagogastroduodenoscopy, Esophageal cancer, Chemotherapy, Prednisolone, Lymph node, Esophagectomy, Internal medicine, Cancer, Adverse effect, Gastroenterology, Radiology, Endoscopy, ImmunotherapyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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3Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| publication_year | 2023 |
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